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Publications

2016

Freezing the Dynamic Gap for Selectivity - Motion-based Design of Inhibitors of the Shikimate Kinase Enzyme
V. Prado, E. Lence, P. Thompson, A. R. Hawkins, C. González-Bello

Targeting the Motion of Shikimate Kinase: Development of Competitive Inhibitors that Stabilize an Inactive Open Conformation of the Enzyme
V. Prado, E. Lence, M. Maneiro, J. C. Vázquez-Ucha, A. Beceiro, P. Thompson, A. R. Hawkins, C. González-Bello

LN-1-255, a penicillanic acid sulfone able to inhibit the class D carbapenemase OXA-48
J. A. Vallejo, M. Martínez-Guitián, J. C. Vázquez-Ucha, C. González-Bello, M. Poza, J. D. Buynak, C. R. Bethel, R. A. Bonomo, G. Bou, A. Beceiro

Study of the Phosphoryl-Transfer Mechanism of Shikimate Kinase by NMR Spectroscopy
V. Prado, E. Lence, J. A. Vallejo, A. Beceiro, P. Thompson, A. R. Hawkins and C. González-Bello

Designing Irreversible Inhibitors—Worth the Effort?
C. González-Bello

Inhibition of Shikimate Kinase and Type II Dehydroquinase for Antibiotic Discovery: Structure-Based Design and Simulation Studies
C. González-Bello

2015

Specific chemical modification of bacterial type I dehydroquinase – opportunities for drug discovery
C. González Bello

Hydrolysis of imidazolidine ligands mediated by CuII: mononuclear, tetranuclear and 1D CuII-amine complexes
M. Fondo, J. Doejo, A. M. García Deibe, J. Sanmartín, C. González Bello, R. Vicente.

Chemical Modification of a Dehydratase Enzyme Involved in Bacterial Virulence by an Ammonium Derivative: Evidence of its Active Site Covalent Adduct
C. González Bello, L. Tizón, E. Lence, J. M. Otero, M. J. van Raaij , M. Martinez Guitian, A. Beceiro, P. Thompson, A. R. Hawkins

Using Surface Enhanced Raman Scattering to Analyze the Interactions of Protein Receptors with Bacterial Quorum Sensing Modulators
C. Costas , V. Lopez Puente , G. Bodelon , C. González Bello , J. PerezJuste , I. Pastoriza Santos, L. M. Liz Marzan