• Do you want to learn more details about our research? Just check out the VIDEO where our colleague Tamara Dacoba explains the key aspects of this publication!
• Publication: Dacoba T.G., Omange R.W., Li H., Crecente-Campo J., Luo M., Alonso M.J., Polysaccharide nanoparticles can efficiently modulate the immune response against an HIV peptide antigen, ACS Nano, 13, 4947–4959 (2019) (DOI: 10.1021/acsnano.8b07662)
21 June 2019 – HIV continues to be one the most challenging viruses in the world, and the development of an effective vaccine against it remains elusive. In this regard, nanoparticles present some unique features that are bringing us closer to find an efficient solution. In this publication, we have shown that by tailoring the physicochemical properties of nanoparticles carrying an HIV antigen, we can modulate the immune responses against this virus. Indeed, we designed nanosystems in which the antigen was attached to the particles in different ways, and also included an adjuvant to boost the immune response. Mice vaccinated with these systems showed different immune responses and, interestingly, different kinetics.
Do you want to learn more details about our research? Just check out the VIDEO where our colleague Tamara Dacoba explains the key aspects of this publication!
