V. a. Review papers

Vila Jato J. L., Blanco J., Alonso M. J., Las Dispersiones Sólidas: Interés Biofarmacéutico (Parte I), Farmacia Clínica, 4, 264-278 (1983)

Vila Jato J. L., Blanco J., Alonso M. J., Las Dispersiones Sólidas: Interés Biofarmacéutico (Parte II), Farmacia Clínica, 5, 29-43 (1983)

Alonso M. J., Blanco J., Vila Jato, J. L., Las Nanopartículas como Sistemas de Liberación de Medicamentos, Revista A.E.F.H., IX, 4, 205-218 (1986)

Vila Jato J. L., Concheiro A., Torres D., Alonso M. J., Disgregantes de Comprimidos: Aspectos Tecnológicos y Biofarmacéuticos, Revista A.E.F.H., XI, 2, 133-148 (1987)

Alonso M. J., Vila Jato J. L., Avances en el Diseño de Formas de Dosificación de Medicamentos de Uso Oftálmico, Revista A.E.F.H. XI, 3 (1987)

Vila Jato J. L., Seijo B., Alonso M. J., Torres J., Interés de los Sistemas Bioadhesivos, Revista A.E.F.H. XII, 3, 217-227 (1988)

Sánchez A., Vila Jato J. L., Alonso M .J., Sistemas de liberación controlada de fármacos a base de polímeros y copolímeros de los ácidos láctico y glicólico, Farmacia Clínica, 8, 824-830 (1991)

Vila Jato J. L., Alonso M. J., Seijo B., Torres D., Sistemas biodegradables para la administración de medicamentos por vía parenteral (I), Industria Farmacéutica, 3, 67-75 (1991)

Vila Jato J. L., Alonso M. J., Seijo B., Torres D., Sistemas biodegradables para la administración de medicamentos por vía parenteral (II), Industria Farmacéutica, 5, 57-65 (1991)

Sánchez A., Calvo P., Vila Jato J.L., Alonso M. J., Ciclosporina A: limitaciones en su utilización clínica y nuevas formas de administración, Farmacia Clínica, 43, 675-695 (1994)

Sánchez A., Tobío M., Alonso M. J., Los polianhídridos: características y aplicaciones en la liberación controlada de moléculas activas, Industria Farmacéutica, 11-12, 83-90 (1994)

Lorenzo-Lamosa M. L., Remuñán-López, Alonso M. J., Interés y aplicaciones del biopolímero chitosan en tecnología farmacéutica , Industria Farmacéutica, 11-12, 71-75 (1994)

Sánchez A., Tobío M., Alonso M. J., Los copolímeros del ácido láctico y glicólico: características y aplicaciones en la liberación de macromoléculas, Industria Farmacéutica, 1-2, 69-76 (1995)

Lorenzo-Lamosa M.L., Remuñán-López C., Alonso M. J., Interés y aplicaciones del biopolímero chitosan en tecnología farmacéutica (II), Industria Farmacéutica, 1-2, 49-52 (1995)

Janes K., Calvo P., Alonso M.J., Polyssacharide nanoparticles for protein delivery, Adv. Drug Deliv. Rev., 47, 83-97 (2001)

Alonso M.J., Sánchez A., The potential of chitosan in ocular drug delivery , J. Pharm. Pharmacol., 55, 1451-1663 (2003)

Köping-Höggard M., Sánchez A., Alonso M.J., Nanoparticles as carriers for nasal vaccine delivery, Expert  Rev. Vaccines, 4, 185-196 (2005)

Prego C., Torres D., Alonso M.J., The potential of chitosan for the oral administration of peptides, Expert Opin. Drug Deliv., 2, 843-854 (2005)

Csaba N., García Fuentes M., Alonso M.J., The performance of nanocarriers for transmucosal drug delivery, Expert Opin. Drug Deliv., 3, 463-478 (2006)

Hervella P., Lozano V., García-Fuentes M., Alonso M. J., Nanomedicine: New challenges and opportunities in cancer therapy, J. Biomed. Nanotechnol. 4, 276-292 (2008)

De la Fuente‌ M., Csaba N., García-Fuentes M.‌, Alonso M. J., Nanoparticles as protein and gene carriers to mucosal surfaces, Nanomedicine, 3, 845-857 (2008)

Csaba N., García Fuentes M., Alonso M.J., Nanoparticles for nasal vaccination, Adv. Drug Deliv. Rev., 61, 140-57 (2009)

Paolicelli P., De la Fuente M., Sánchez A., Seijo B., Alonso M.J., Chitosan nanoparticles for drug delivery to the eye., Expert Opin. Drug Deliv., 6, 239-253 (2009)

Alonso-Sande M., Teijeiro-Osorio D., Remuñán-López C., Alonso M.J., Glucomannan, a promising polysaccharide for biopharmaceutical purposes, Eur. J. Pharm. Biopharm., 72, 453–462 (2009)

De la Fuente M., Raviña M., Paolicelli P., Sanchez A., Seijo B., Alonso M.J., Chitosan-based nanostructures: a delivery platform for ocular therapeutics, Adv. Drug Deliver. Rev., 62, 100–117 (2010)

Lollo G., Rivera Rodríguez G., Torres D., Alonso M.J., Nanoterapias oncológicas: aplicaciones actuales y perspectivas futuras, Anales de la Real Academia Nacional de Farmacia, 77, No 4 (2011)

Herrero E.P., Alonso M.J., Csaba N, Polymer-based oral peptide nanomedicines, Therapeutic Delivery, 3, 657-668 (2012)

Garcia-Fuentes M., Alonso M.J., Chitosan-based nanocarriers: Where do we stand?, J. Control. Rel., 161, 496-504 (2012)

Correia-Pinto J., Csaba N., Alonso M.J., Vaccine delivery carriers: Insights and future perspectives, Int. J. Pharmacol., 440, 27-38 (2013)

Pereira Gomes C, Ferreira Lopes C.D, Duarte Moreno P.D., Varela-Moreira A., Alonso M.J., Pêgo A.P., Translating chitosan to clinical delivery of nucleic acid-based drugs, MRS Bulletin, 39, 60-70 (2014)

Alonso M, Lozano M.V, Lopez R, Alonso M.J, Nanomedicamentos contra el cancer, Investigación y Ciencia, 450 (2014)

Torres-Andón F., Alonso M.J., Nanomedicine and cancer immunotherapy – targeting immunosuppressive cells, J. Drug Targeting, 23, 656-671 (2015)

Reimondez-Troitiño S., Csaba N., Alonso M.J., de la Fuente M., Nanotherapies for the treatment of ocular diseases, Eur. J. Pharm. Biopharm. 95, 279-293 (2015)

Cordeiro A.S, Alonso M.J, de la Fuente M., Nanoengineering of vaccines using natural polysaccharides, Biotechnology Advances, 33, 1279-1293 (2015)

Cordeiro A.S., Alonso M.J., Recent advances in vaccine delivery, Pharmaceutical Patent Analyst, 5, 49-73 (2016)

Zhigao N., Conejos-Sánchez I., Griffin B, O’Driscoll C., Alonso M.J., Lipid-based nanocarriers for oral peptide delivery, Adv. Drug Deliver. Rev., 106-Part B, 332-354 (2016)

Aguirre T.A.S., Teijeiro-Osorio D., Rosa M., Coulter I.S., Alonso M.J., Brayden D.J., Current status of selected oral peptide technologies in advanced preclinical development and in clinical trials, Adv. Drug Deliver. Rev., 106-Part B, 223-241 (2016)

Reimondez-Troitiño S., Alcalde I., Csaba N., Íñigo Portugués A., De la Fuente M., Bech F., Riestra A. C., Merayo-Lloves J., Alonso M.J., Polymeric nanocapsules: a potential new therapy for corneal wound healing, Drug Delivery and Translational Research, 6(6), 708-721 (2016).

Griffin B.T., Guo J., Presas E. , Donovan M.D., Alonso M.J., O’Driscoll C.M., Pharmacokinetic, pharmacodynamic and biodistribution following oral administration of nanocarriers containing peptide and protein drugs, Adv. Drug Deliver. Rev., 106-Part B, 367-380 (2016)

Abellan-Pose R., Csaba N., Alonso M.J., Lymphatic Targeting of Nanosystems for Anticancer Drug Therapy, Current Pharmaceutical Design, 22, 1194-1209 (2016)

Cadete ‌A., Alonso M.J., Targeting cancer with hyaluronic acid-based nanocarriers: recent advances and translational perspectives, Nanomedicine, Vol. 11, 2341-2357 (2016)

Brayden D., Alonso M.J., Oral delivery of peptides – Opportunities and issues for translation, Adv. Drug Deliver. Rev., 106-Part B, 193-195 (2016)

Saraiva S.M., Castro-López V., Pañeda C., Alonso M.J., Synthetic nanocarriers for the delivery of polynucleotides to the eye, Eur. J. Pharm. Sci., 103, 5-18 (2017) (PDF link)

Santalices I., Gonella A., Torres D., Alonso, M.J., Advances on the formulation of proteins using nanotechnologies, J. Drug Del. Sci. Tech ., 42, 155-180 (2017)

G. Dacoba T., Olivera A., Torres D., Crecente-Campo J., Alonso M.J., Modulating the immune system through nanotechnology, Seminars in Immunology , 34,78-102 (2017)

Torres Andón F., Digifico E., Maeda A., Erreni M., Mantovani A., Alonso M.J., Allavena P., Targeting tumor associated macrophages: The new challenge for nanomedicine, Seminars in Immunology, 34,103-113 (2017)

Samaridou E., Alonso M.J., Nose-to-brain peptide delivery – The potential of nanotechnology, Bioorg Med Chem,, 26, 2888-2905 (2018) (https://doi.org/10.1016/j.bmc.2017.11.001)

Durán-Lobato M., Zhigao N., Alonso M.J., Oral delivery of biologics for precision medicine, Adv. Mater. 2019, 1901935 (DOI: 10.1002/adma.201901935)

Del Rio-Sancho S., Castro-Lopez V., Alonso M.J., Enhancing cutaneous delivery with laser technology: almost there, but not yet, J. Control Rel., 315, 150-165 (2019) https://doi.org/10.1016/j.jconrel.2019.09.014

Leong, H.S., Butler, K.S., Brinker, C.J. et al. On the issue of transparency and reproducibility in nanomedicine. Nat. Nanotechnol. ,14, 629–635 (2019)

Robla S., Alonso M.J., Csaba N., Polyaminoacid-based nanocarriers: a review of the latest candidates for oral drug delivery, Expert Opin. Drug Deliv., 17 (8), 1081-1092 (2020)

Berrecoso G., Crecente-Campo J., Alonso M.J., Unveiling the pitfalls of the protein corona of polymeric drug nanocarriers, Drug Deliv. and Transl. Res., 10, 730–750 (2020)

Abbadessa A., Crecente-Campo J., Alonso M.J., Engineering Anisotropic Meniscus: Zonal Functionality and Spatiotemporal Drug Delivery, Tissue Engineering Part B: Reviews, (2020) http://doi.org/10.1089/ten.teb.2020.0096

Dacoba T. G., Anthiya S., Berrecoso G., Fernández-Mariño I., Fernández-Varela C., Crecente-Campo J., Teijeiro-Osorio D., Torres-Andón F., Alonso M.J., Nano‐Oncologicals: A Tortoise Trail Reaching New Avenues, Adv. Funct. Mater., 2009860 (1-36) (2021). https://doi.org/10.1002/adfm.202009860

Quattrini, F., Berrecoso, G., Crecente-Campo, J. et al. Asymmetric flow field-flow fractionation as a multifunctional technique for the characterization of polymeric nanocarriers. Drug Deliv. and Transl. Res. (2021). https://doi.org/10.1007/s13346-021-00918-5

M. Durán-Lobato, A. María López-Estévez, A. Sara Cordeiro, T. Gómez Dacoba, J.Crecente-Campo, D. Torres, M. José Alonso, Nanotechnologies for the delivery of biologicals: historical perspective and current landscape, Advanced Drug Delivery Reviews, 176, 113899 (2021), https://doi.org/10.1016/j.addr.2021.113899.

Joyce P., Allen C.J., Alonso M.J. et al., A translational framework to DELIVER nanomedicines to the clinic, Nat. Nanotechnol. 19, 1597–1611 (2024). https://doi.org/10.1038/s41565-024-01754-7

López Estévez A.M., Lapuhs P., Piñeiro Alonso L., Alonso M.J., Personalized cancer nanomedicine: Overcoming biological barriers for intracellular delivery of biopharmaceuticals, Adv. Materials, 36, 2309355 (2024)

Durán-Lobato M., Tovar S., Cuñarro J., Ramos-Membrive R., Peñuelas I., Marigo I., Benetti F., Chenlo M., V. Álvarez C., Ildikó V., Urbanics R., Szebeni J., Alonso M.J., Bioinspired orthogonal-shaped protein–biometal nanocrystals enable oral protein absorption, J. Control. Rel. 377, 17-36 (2025)

Stephen W. Linderman, Louis DeRidder, Lucía Sanjurjo, Michael B. Foote, María José
Alonso, Ameya R. Kirtane, Robert Langer, Giovanni Traverso, Enhancing immunotherapy with tumour-responsive nanomaterials, Nature reviews clinical oncology, 22, 262–282 (2025). https://doi.org/10.1038/s41571-025-01000-6

Ibeas Moreno E., Alonso M.J., Abbadessa A., Intraocular injectable hydrogels for the delivery of cells and nanoparticles, Materials Today Bio, 32, 101767 (2025), https://doi.org/10.1016/j.mtbio.2025.101767

V. b. Book chapters

Alonso M. J., Sistemas sólidos coloidales (nanopartículas y nanocápsulas) constituídos a base de polímeros acrílicos, in: Modernos Métodos de Administración de Medicamentos, Vila Jato J.L., Seijo B., Alonso, M.J. y Torres, D., Eds. Farmaindustria., 1990, pp. 123-174.

Alonso M. J., Langer R., Biodegradable controlled release microspheres for macromolecules and proteins, in: Profiles on Biotechnology, Villa T. y Abalde J. Eds., USC, 1992, pp. 555-564.

Gupta R., Alonso M. J., Langer R., Siber G., Development of a single-dose tetanus toxoid based on controlled release from biodegradable and biocompatible polyester microspheres Vaccine 93, Cold Spring Harbor Laboratory Press, 1993, pp. 391-396.

Gopferich A., Gref R., Minamitake Y., Shield L., Alonso M. J., Tabata Y., Langer R. , Drug delivery from bioerodible polymers: systemic and intravenous administration, in: Formulation and Delivery of proteins and peptides, Cleland J.L & Langer R. Eds. American Chemical Society Symposium Series, 1994, pp. 241-277.

Alonso M.J., Nanoparticulate drug carrier technology, in: Microparticulate Systems for the Delivery of Proteins and Vaccines, Cohen S. and Newman M. Eds., Marcel Dekker, Inc., 1996, pp. 210-243.

Schwendeman S.P., Costantino H., Gupta R.K., Tobío M., Chang A., Alonso M.J., Siber G.R., Langer R., Strategies for stabilizing tetanus toxoid toward the development of a single-dose tetanus vaccine, in: Developments in Biological Standarization: New Approaches to Stabilization of Vaccines Potency, Brown F. Ed. WHO Series, 1996, 87, pp. 293-306.

Remuñán-López C., Alonso M.J., Microencapsulación de medicamentos, in:  Tecnología Farmacéutica. Volumen I: Aspectos Fundamentales de los Sistemas Farmacéuticos y Operaciones Básicas, Vila Jato J.L. Ed. , Editorial Síntesis, 1997, pp. 577-609.

Remuñán López C., Lorenzo-Lamosa M. L., Portero A., Vila Jato J. L., Alonso M. J., Site specific drug delivery using chitosan microparticles, in: Advances in Chitin Sciences, Domard S., Roberts G. A. F. y Varum K. Eds., 1997, pp.600-607.

Gref R., Quellec P., Alonso M.J., Tobio M., Lück M., Müller R.H., Dellacherie E. , PEG-coated nanospheres: surface optimization and therapeutic aplications, in: Targeting of Drugs: Strategies for Stealth Therapeutic Systems, NATO ASI Series, 1998, pp.275-290

Portero A., Alonso M.J., Remuñán-López C. , Chitosan bilayered devices for buccal administration of insulin, in: Chitosan in Pharmacy and chemistry, R.A.A. Muzarelli and C. Muzarelli Eds., 2001 pp.21-30

Garcia M., Torres-Lugo M., Alonso M. J., Peppas N. A.  , Biointeractions of pH-Sensitive Poly(methacrylic acid-g-ethyleneglycol) Hydrogel Microspheres with the Caco-2 Model Cell Line”, in: New Trends in Polymers for Oral and Parenteral Administration: From Design to Receptors, G. Barratt, D. Duchêne, F. Fattal and J.Y. Legendre, Eds., Editions de Santé, Paris, 2001, pp.386-389.

Vila A., Sánchez A., Tobío M., Alonso M.J., Polymers for vaccination, in: New Trends in Polymers for Oral and Parenteral Administration: From Design to Receptors, G. Barratt, D. Duchêne, F. Fattal and J.Y. Legendre, Eds., Editions de Santé, Paris, 2001.

Alonso M.J., Sánchez A., Biodegradable nanoparticles as new transmucosal drug carriers, in: Carrier based drug delivery (Svenson, S., Ed.), ACS Series (879), American Chemical Society, Washington, DC, 2004, pp. 283-295.

Garcia-Fuentes M., Torres D., Alonso M.J., Polymer-coated lipid nanostructures as carriers for oral peptide delivery, in: Bulletin Technique Gattefossé, Nº 97, 2004, pp.57-68.

Csaba N., Pérez C., Sánchez A., Alonso M. J., in: Nanoparticles made of poly(lactic acid) and poly(ethylene oxide) as carriers of plasmid DNA, in: Polymeric gene delivery: Principles and applications (Amiji, M.M., Ed.). CRC Press, Boca Raton, 2005, pp.367-386.

Csaba N., Sánchez A., Alonso M.J., Poly(lactic acid) and poly(ethylene oxide) nanoparticles as carriers for gene delivery, in: Gene Transfer: Delivery and Expression of DNA and RNA (Laboratory Manual) (Friedmann,T., Rossi, J., Eds.). Laboratory Press, Cold Spring Harbor, 2006, pp.555-560.

Sanchez A., Alonso M.J., Nanoparticular carriers for ocular drug delivery, in: Nanoparticulates as drug carriers (Torchilin, Vladimir, Ed.), World Scientific- Imperial College Press, 2006, pp.649-674.

Garcia Fuentes M.,  Csaba N., Alonso M.J., Nanostructured chitosan carriers for oral protein and peptide delivery, in: Drug Delivery 2007, Ed. Touch Briefings, 2007, pp.16-19.

Alonso M.J., Prego C., García-Fuentes M., Polysaccharide-based Nanoparticles as Carriers for Drug and Vaccine Delivery, in: Nanoparticles for Pharmaceutical Applications, A. J. Domb, Y. Tabata, R. Kumar and S. Farber Eds., 2007, pp.136-147

Alonso M.J., Goycoolea F.M., Higuera-Ciapara I., Chitosan-polysaccharide blended nanoparticles for controlled drug delivery, in: Natural-based polymers for biomedical applications, Woodhead Publishing Limited, 2008, pp.644-679

Goycoolea, F., Remuñán M., Alonso M.J., Nanosistemas a base de polisacáridos: Quitosano, in: Nanotecnología Farmacéutica, Realidades y Posibilidades Farmacoterapéuticas, Instituto de España, Real Academia Nacional de Farmacia, Monografía XXVIII, Editor: José Luis Vila Jato, 2009, p.p.103-131.

Vicente, S., Sánchez, A., Alonso M.J., Nanovacunas, in: Nanotecnología Farmacéutica, Realidades y Posibilidades Farmacoterapéuticas, Instituto de España, Real Academia Nacional de Farmacia, Monografía XXVIII, Editor: José Luis Vila Jato, 2009, p.p.76-98.

Carvalho E.L.S., Grenha A., Remuñán-López C.,  Alonso M.J., Seijo B, Mucosal Delivery of Liposome–Chitosan Nanoparticle Complexes, in: Methods in Enzymology, Liposomes, Part G. Vol. 465, Nejat  Düzgünes Ed., 2009, p.p. 289-312.

Csaba N., Sanchez Barreiro A., Alonso M.J. , Preparation of Poly(Lactic Acid) (PLA) and Poly(Ethylene Oxide) (PEO) Nanoparticles as Carriers for Gene Delivery, Cold Spring Harb Protoc., (doi:10.1101/pdb.prot5468), 2010.

Hervella P., Lollo G., Oyarzun-Ampuero F., Rivera G., Torres D., Alonso M.J., Nanocapsules as Carriers for the Transport and Targeted Delivery of Bioactive Molecules, Nanocomposite particles for bio-aplications: Materials and bio-interfaces, Tito Trindade & Ana Luisa Daniel Eds., Pan Stanford Publishing, 2011, p.p.45-67.

Alonso M.J. and Couvreur P., Historical view of the design and development of nanocarriers for overcoming biological barriers, in: Nanostructured Biomaterials for Overcoming Biological Barriers, Alonso M.J. and Csaba N. (Eds), RSC Drug Discovery Series, RSC Publising, 2012, pp 3-38.

Vila-Sanjurjo C., Fuenzalida J.P., Menchicchi B., Coelho D., Engwer C., Hoffman S., Pereira S., Remuñán-López C., Alonso M.J., Vidal A., Moerschbacher B., Kollenbrock S., Fetzner S., Philipp B., Goycoolea F.M., Chitosan-based nanomaterials for drug delivery and antibiotic-free bacterial control, In: Nanotechnology 2013: Bio Sensors, Instruments, Medical, Environment and Energy, NSTI (Ed), CRC Press, 2013, p.p.217-220.

Teijeiro C., McGlone A., Csaba N., Garcia-Fuentes M., Alonso, M.J., Polysaccharide-based nanocarriers for drug delivery, In: Handbook of Nanobiomedical Research (M.L. Yarmush and D. Shi, series Eds.), Vol. 3 (V. Torchilin Ed.), World Scientific Ed., 2014, pp. 235-277.

De la Fuente M., Langer R., Alonso M.J., Nanotechnology Approaches for Cancer Immunotherapy and Immunomodulation, In: Nano-Oncologicals: new targeting and delivery approaches, Advances in Delivery Science and Technology Series, Alonso M.J. and Garcia-Fuentes M. Eds, Springer, 2014, p.p.215-242.

Borrajo E., Vidal A., Alonso M.J., Garcia-Fuentes M., How Regenerative Medicine Can Benefit from Nucleic Acids Delivery Nanocarriers, p.p. 285-336, In Polymers in Regenerative Medicine: Biomedical Applications from Nano- to Macro-Structures, Manuel Monleón Pradas and María J. Vicent (EDs), Willey, ISBN: 978-0-470-59638-8 (2015)

Alonso-Sande M., Csaba N., Alonso M.J., New perspectives in oral peptide and protein delivery: from nanocarrier design to in vivo effectiveness, Advances and challenges in the oral delivery of macromolecules, Future Science Ltd, Unitec House, 2 Albert Place, London, N3 1QB, UK. eBook. (2016)

V. c. Books

Nanostructured Biomaterials for Overcoming Biological Barriers, Alonso M.J. and Csaba N. Eds., RSC Drug Discovery Series, RSC Publising, Cambridge, UK, ISBN: 978-1-84973-363-2 (2012)

Nano-Oncologicals: new targeting and delivery approaches, Advances in Delivery Science and Technology Series, Alonso M.J. and Garcia-Fuentes M. Eds, Springer, New York, USA, ISBN: 978-3-319-08083-3 (2014)

V. d. Original articles

Vila Jato J.L., Concheiro A., Llabrés M., Alonso M.J., Biodisponibilidad Oral del Cefadroxilo: Influencia de la Alimentación, Arch. Farmaco. Toxico. VIII, 171-177 (1982)

Vila Jato J.L., Alonso M.J., Blanco J., Dispersiones Sólidas de Tolbutamida en Polietilénglicoles: Influencia del Método de Preparación y del Peso Molecular de los Polímeros, C.I.F. 3, 204-209 (1984)

Vila Jato J.L., Blanco J., Alonso M.J., The Effect of the Molecular Weight of Polyethylene Glycol on the Bioavailability of Paracetamol-Polyethylene Glycol Solid Dispersions, J. Pharm. Pharmacol. 38, 126-128 (1986)

Vila Jato J.L., Alonso M.J., Biopharmaceutical Study of Glybornuride in Polyethylene Glycol Systems, Drug Dev. Ind. Pharm. 12 (5), 701-711 (1986)

Vila Jato J.L., Alonso M.J., Blanco, J., The Aging of Solid Dispersions of Glybornuride in Polyethylene Glycol 6000, Drug Dev. Ind. Pharm. 12 (10), 1545-1552 (1986)

Alonso M.J., Maincent P., Blanco J., Vila Jato, J.L., Etude de Stabilité de la Dispersion Solide Glybornuride-P.E.G. 20000: Caracterisation Physico-chimique et Evaluation Biopharmacetique, S.T.P. Pharma, 3, 569-574 (1987)

Henry-Micheland M.J., Alonso M.J., Andremont A., Sauzieres J., Couvreur P., Attachment of Antibiotics to Nanoparticles: Preparation, Drug-Release and Antimicrobial Activity In Vitro, Int. J. Pharmacol., 35, 121-127 (1987)

Alonso M.J., Maincent P., García Arias T., Vila Jato J.L., A Comparative Biopharmaceutical Study of Fresh and Ageing Tolbutamide-Polyethyleneglycols Solid Dispersions, Int. J. Pharmacol., 42, 27-33 (1988)

Youssef M., Fattal E., Alonso M.J., Roblot-Treupel L., Sauzires J., Tancrede C., Omns A., Couvreur P., Andremont A., Effecctiveness of Nanoparticle-Bound Ampicillin in Treatment of Listeria monocitogenes Infection in Athymic Nude Mice, Antimicrob. Agents Chemother., 32, 8, 1204-1207 (1988)

Torres D, Seijo, B, García-Encina G., Alonso M.J., Vila Jato J.L., Microencapsulation of ion-exchange resins by interfacial nylon polimerization, Int J. Pharmaceut., 59, 9-17 (1990)

Alonso M.J., Sánchez A., Seijo B., Torres D., Vila Jato J.L., Joint effects of monomer and stabilizer concentrations on physico-chemical characteristics of Poly(butyl 2-cyanoacrylate) nanoparticles, J. Microencapsulation, 7, 517-526 (1990)

Alonso M. J., Losa C., Calvo P., Vila Jato J., Approaches to improve the association of amikacin sulphate to poly(alkylcyanoacrylate) nanoparticles, Int J. Pharmaceut., 68, 69-76 (1991)

Losa C., Calvo P., Castro E., Vila Jato J. L., Alonso M. J., Improvement of ocular penetration of amikacin sulphate by association to poly(butylcyanoacrylate) nanoparticles, J. Pharm. Pharmacol., 43, 548-552 (1991)

Egea M. A., Valls O., Alsina M. A., García M. L., Losa C., Vila J. L., Alonso M. J., Interaction of amikacin loaded nanoparticles with phosphatidylcholine monolayers as membrane models, Int. J. Pharmaceut., 67, 103-112 (1991)

Julienne M.C., Alonso M.J., Gómez Amoza J. L., Benoit J. P., Preparation of poly(D,L-lactide/glycolide) nanoparticles of controlled particle size distribution: application of experimental designs, Drug Dev. Ind. Pharm., 18, 1063-1077 (1992)

Losa C., Alonso M.J., Vila J.L., Orallo F., Martinez J. Saavedra J.A., Pastor J.C., Reduction of cardiovascular side effects associated with ocular administration of metipranolol by inclusion in polymerc nanocapsules, J. Ocular Pharmacol.,  8, 191-198 (1992)

Losa C. M., Marchal-Heussler L., Orallo F., Vila Jato J.L., Alonso M.J., Design of new formulations for topical ocular administration: polymeric nanocapsules containing metipranolol, Pharm. Res., 10, 80-87 (1993)

Sánchez A., Vila Jato J.L., Alonso M.J., Development of biodegradable microspheres and nanospheres for the controlled release of cyclosporin A, Int. J. Pharmaceut., 99, 263-273 (1993)

Alonso M. J., Cohen S., Park T.G., Gupta R. K., Siber G., Langer R., Determinants of the release of tetanus toxoid from polyester microspheres, Pharm. Res., 10, 945-953 (1993)

Alonso M. J., Gupta R. K., Min  C., Siber G., Langer R., Biodegradable microspheres as controlled release tetanus toxoid delivery systems, Vaccine, 12, 299-306 (1994)

Calvo P., Thomas, Alonso M.J., Vila Jato J.L., Robinson J., Study of the mechanisms of interaction of poly-E-caprolactone nanocapsules with the cornea by confocal laser scanning microscopy, Int. J. Pharmaceut., 103, 283-291 (1994)

Gopferich A., Alonso M.J., Langer R., Development and characterization of microencapsulated microspheres, Pharm. Res., 11, 1568-1574 (1994)

Park T. G., Alonso M.J., Langer R., Controlled release of proteins from poly(L-lactic acid) coated polyisobutylcyanoacrylate microcapsules, J. Appl. Polymer. Sci., 52, 1797-1807 (1994)

Cohen S., Alonso M. J., Langer R., Novel approaches to controlled release antigen delivery, Int. J. Tech. Health Care, 10, 121-130 (1994)

Sánchez A., Alonso M.  J., Poly (D, L-lactide-co-glycolide) micro and nanospheres as a way to prolong blood/plasma levels of subcutaneously injected cyclosporin A, Drug Delivery, 2, 21-28 (1995)

Sánchez A., Seoane R., Quireza O., Alonso M.J., Poly(DL-lactide-co-glycolide) micro and nanospheres as a way to prolong blood/plasma levels of subcutaneously injected Cyclosporin A., Eur. J. Pharm. Biopharm., 41, 31-37 (1995)

Calvo P., Sánchez A., Martinez J., López M.I., Calonge M. Pastor J.C., Alonso M.J., Polyester nanocapsules as new topical ocular delivery systems for Cyclosporin A, Pharm. Res., 13, 126-130 (1996)

Calvo P., Vila Jato J.L., Alonso M. J., Comparative in vitro evaluation of several colloidal systems, nanoparticles, nanocapsules and nanoemulsions, as ocular drug carriers, J. Pharm. Sci., 85, 530-536 (1996)

Calvo P., Vila-Jato J.L., Alonso M. J., Improved ocular bioavailability of indomethacin by novel ocular drug carriers, J. Pharm. Pharmacol., 22, 1147-1152 (1996)

Sánchez A., Gupta R., Alonso M.J., Siber G., Langer R., Pulsed controlled release system for potential use in vaccine delivery, J. Pharm. Sci., 85, 547-552 (1996)

Calvo P., Remuñán-López C., Vila-Jato J.L., Alonso M. J., Development of positively charged colloidal drug carries: chitosan-coated polyester nanocapsules and submicron-emulsions, Colloid. Polymer Sci. 275, 46-53 (1997)

Calvo P., Remuñán-López C., Vila-Jato J.L., Alonso M. J., Novel hydrophilic chitosan-polyethylene oxide nanoparticles as protein carriers, J. Appl. Polymer Sci., 63, 125-132 (1997)

Cuña M., Lorenzo-Lamosa M.L., Torres D., Vila-Jato J.L., Alonso M. J., PH-dependent cellulosic microspheres containing cefuroxime axetil: stability and in vitro release behaviour, Drug Dev. Ind. Pharm., 23, 259-265 (1997)

Blanco D., Alonso M. J., Development and characterization of protein-loaded poly(lactide-co-glycolide) nanospheres, Eur. J. Pharm. Biopharm., 43, 287-294 (1997)

Calvo P., Vila-Jato J.L., Alonso M. J., Evaluation of cationic polymer-coated nanocapsules as ocular drug carriers, Int. J. Pharmaceut., 153, 41-50 (1997)

Calvo P., Vila-Jato J.L., Alonso M. J., Effect of lysozyme on the stability of polyester nanocapsules: stabilization approaches, Biomaterials, 18, 1305-1310 (1997)

Gupta R. K., Alroy J., Alonso M. J., Langer R., Siber G. R., Chronic local tissue reactions, long term immunogenicity and immunologic priming of mice and guinea pigs to tetanus toxoid encapsulated in biodegradable polymer microspheres composed of poly lactide-co-glycolide polymers, Vaccine, 15, 1716-1723 (1997)

Lorenzo-Lamosa M. L., Cuña M., Torres D., Vila-Jato J.L., Alonso M. J., Development of a microencapsulated form of cefuroxime axetil using pH-sensitive acrylic polymers, J. Microencapsulation, 14, 607-616 (1997)

Calvo P., Remuñán-López C., Vila-Jato J.L., Alonso M. J., Chitosan and Chitosan/Ethylene Oxide-Propylene Oxide Block Copolymer Nanoparticles as Novel Carriers for Proteins and Vaccines, Pharm. Res., 14, 1431-1436 (1997)

Juberías J.R., Calonge M., Gómez S., López M.I., Calvo P., Herreras J.M., Alonso M. J., Efficacy of topical cyclosporine-loaded nanocapsules on keratoplasty rejection in the rat, Curr. Eye Res., 17, 39-46 (1998)

Tobío M., Gref R., Sánchez A., Langer R., Alonso M.J., Stealth PLA-PEG nanoparticles as protein carriers for nasal administration, Pharm. Res., 15, 270-275 (1998)

Zambaux M.F., Bonneaux F., Gref R., Maincent P., Dellacherie E., Alonso M.J., Labrude, Vigneron C., Influence of experimental parmeters on the characteristics of PLA nanoparticles prepared by a double emulsion method, J. Control. Rel., 50, 31-40 (1998)

Remuñán-López C., Lorenzo-Lamosa M.L., Vila-Jato J.L., Alonso M. J., Development of new chitosan-cellulose multicore microparticles for controlled drug delivery, Eur. J. Pharm. Biopharm., 45, 49-56 (1998)

Gaspar M., Blanco D., Cruz M.E.M., Alonso M. J., Formulation of L-asparginase loaded poly(lactide-co-glycolide) nanoparticles: influence of polymer properties on enzyme loading, activity and in vitro release, J. Control. Rel., 52, 53-62 (1998)

Swendeman S., Tobío M., Joworowicz M., Alonso M.J., Langer R., New strategies for the microencapsulation of tetanus vaccine, J. Microencapsulation, 15, 299-318 (1998)

Lorenzo-Lamosa M.L., Remuñán-Lopez C., Vila-Jato J.L., Alonso M. J., Design of microencapsulated chitosan microspheres for colonic drug delivery, J. Control. Rel., 52, 109-118 (1998)

Blanco D., Alonso M. J., Protein encapsulation and release from poly (lactide-co-glycolide) microspheres: effect of the protein and polymer properties and of the co-encapsulation of surfactants, Eur. J. Pharm. Biopharm., 45, 285-294 (1998)

Quellec P., Gref R., Perrin L., Dellacherie E., Sommer F., Verbavatz J.M., Alonso M. J., Protein encapsulation within PEG-coated nanospheres I: Physicochemical characterization, J. Biomed. Mater. Res., 42, 45-54 (1998)

Lorenzo-Lamosa M. L., Remuñán-Lopez C., Vila-Jato J. L., Alonso M. J., Design and evaluation of chitosan/ethylcellulose mucoadhesive bilayered devices for buccal drug delivery, J. Control. Rel., 55, 143-152 (1998)

Tobío M., Alonso M.J., Study of the inactivation process of the tetanus toxoid in contact with poly(lactic/glycolic acid) degrading microspheres, S.T.P. Pharma Sci., 8, 303-310 (1998)

Williams R.O., Barron M.K., Alonso M.J., Remuñán-López C., Investigation of a pMDI system containing chitosan microspheres and P134a, Int. J. Pharmaceut., 174, 209-222 (1998)

Portero, A., Remuñán-López, C., Vila-Jato, J. L., Effect of chitosan and chitosan glutamate enhacing the dissolution properties of the poorly water soluble drug nifedipine, Int. J. Pharmaceut., 175, 75-84 (1998)

Quellec P., Gref R., Perrin L., Dellacherie E., Sommer F., Verbavatz J.M., Alonso M. J., Protein encapsulation within PEG-coated nanospheres II: In vitro release, J. Biomed. Mater. Res., 47, 388-395 (1999)

Tobío M., Nolley J., Y. Guo, J. McIver, Alonso M.J., A novel system based on a PLGA/Poloxamer blend as a tetanus toxoid delivery vehicle, Pharm. Res., 16, 682-688 (1999)

Sánchez A., Villamayor B., Guo Y., McIver J., Alonso M.J., Formulation strategies for the solubilization of tetanus toxoid in poly(lactide-co-glycolide) microspheres, Int. J. Pharmaceut., 185, 255-266 (1999)

Fernández Urrusuno R., Calvo P., Remuñán-López C., Vila Jato J.L., Alonso M.J., Enhancement of nasal absorption of insulin using chitosan nanoparticles, Pharm. Res., 16, 1576-1581 (1999)

Fernández Urrusuno R., Romaní D., Calvo P., Vila Jato J.L., Alonso M.J., Development of a freeze-dried formulation of insulin-loaded chitosan nanoparticles intended for nasal administration, S.T.P. Pharma  Sci., 9, 429-436 (1999)

Tobío M., Schewndeman P.S., Guo Y., J. McIver J., Langer R., Alonso M.J., Improved immunogenicity of a core-coated tetanus toxoid delivery vehicle, Vaccine, 18, 618-622 (2000)

Portero A., Remuñán-López C., Lemos M., Vila Jato J.L., Núñez M.J., Alonso M.J., Chitosan microspheres for specifice delivery of amoxicillin to the gastric cavity, S.T.P. Pharma  Sciences, 10, 69-76 (2000)

Tobío M., Sánchez A., Vila A., Soriano I., Evora C., Vila Jato J.L., Alonso M.J., The role of PEG on the stability in digestive fluids and in vivo fate of PEG-PLA nanoparticles following oral administration, Colloid Surf. B-Biointerfaces, 18, 315-323 (2000)

Gref R. Quellec P., Sanchez A., Calvo P., Dellacherie E., Alonso M.J., Development and characterization of CyA-loaded PLA-PEG micro and nanoparticles.Comparison with conventional PLA particulate carriers, Eur. J. Pharm. Biopharm., 51, 2, 111-118 (2001)

Cuña M., Alonso M.J., Torres D., Preparation and in vivo evaluation of mucoadhesive microparticles containing amoxycillin-resin complexes for site-specific antibiotic delivery in the stomach, Eur. J. Pharm. Biopharm., 51, 199-205 (2001)

Janes K., Fresneau M.P., Marazuela A., Fabra A., Alonso M.J., Chitosan nanoparticles as delivery sytems for doxorubicin, J. Control. Rel., 73, 255-267 (2001)

Pérez C., Sánchez A., Putnam D., Ting D., Langer R., Alonso M.J., Poly (lactic acid)-poly(ethylene glycol) nanoparticles as new carriers for the delivery of plasmid DNA, J. Control. Rel., 75, 211-224 (2001)

De Campos A., Sánchez A., Alonso M.J., Chitosan nanoparticles: a new vehicle for the improvement of the ocular retention of drugs. Application to Cyclosporin A, Int. J. Pharmaceut., 224, 159-168 (2001)

Vila A., Sánchez A., Tobío M., Calvo P., Alonso M.J., Design of biodegradable particles for protein delivery, J. Control. Rel., 78, 15-24 (2002)

Vila A., Sánchez A., Pérez C., Alonso M.J., PLA-PEG nanospheres: new carriers for transmucosal delivery of proteins and plasmid DNA, Polym. Adv. Tech., 13, 1-8 (2002)

Portero A., Remuñán-López C., Criado M.T., Alonso M.J., Reacetylated chitosan microspheres for controlled delivery of antimicrobial agents to the gastric mucosa, J. Microencapsulation, 19, 797-809 (2002)

Behrens I., Vila Pena A., Alonso M.J., Kissel T., Comparative uptake studies of bioadhesive and non-bioadhesive nanoparticles in human epithelial cell lines and rats: the effect of mucus on particle adsorption and transport, Pharm. Res., 19, 1185-1193 (2002)

Vallelado A.I., López M.I., Calonge M., Sánchez A., Alonso M.J., Efficacy and safety of microspheres of cyclosporin A, a new systemic formulation to prevent corneal graft rejection in rats, Current Eye Res., 24, 39-45 (2002)

García M., Torres D., Alonso M.J., Design of lipid nanoparticles for oral delivery of hydrophilic macromolecules, Colloid. Surf., B: Biointerfaces, 27, 159-168 (2002)

Alonso M.J., Janes K., Depolymerized chitosan nanoparticles for protein delivery: preparation and characterization, J. Appl. Polymer Sci., 88, 12, 2769-2776 (2003)

Diebold Y., de Salamanca A.E., Jarrin M., Callejo S., Vila A., Alonso M.J., Uptake of bioadhesive nanoparticles in a normal human conjunctiva (NHC) epithelial cell line, Invest. Ophthalmol. Vis. Sci., 44, 3785 (2003)

Sánchez A., Tobío M. , González L., Fabra A., Alonso M.J., Biodegradable micro and nanoparticles as long-term delivery vehicles for interferon alpha, Eur. J. Pharm. Sci., 18, 221-229 (2003)

De Campos A., Sánchez A., Gref. R., Calvo P., Alonso M.J., The effect of a PEG coating vs. a chitosan coating on the interaction of drug colloidal carriers with the ocular   mucosa, Eur. J. Pharm. Sci., 20, 73-81 (2003)

Garcia M., Prego C., Torres D., Alonso M.J., Polymer-lipid nanostructures as carriers for oral peptide delivery, Eur. J. Pharm. Sci., 23, S15-S16, (2004)

Vila A., Sánchez A., Janes K. A., Behrens I., Kissel T., Vila Jato J. L., Alonso M. J., Low molecular weight chitosan nanoparticles as new carriers for nasal vaccine delivery, Eur. J. Pharm. Biopharm., 57, 123-132 (2004)

Diebold Y., Jarrin M., Callejo S., Carvalho E.L.S., Seijo B., Alonso M.J., Study of liposome-chitosan nanoparticles for drug delivery in normal human conjunctiva epithelial systems in vitro, Invest. Ophthalmol. Vis. Sci., U567-U567, 1487 Suppl. 1 (2004)

Alonso M.J., Nanomedicines for overcoming biological barriers, Biomed. Pharmacother., 58, 168-172 (2004)

Vila A., Sánchez A., Évora C., Soriano I., Vila Jato J.L., Alonso M. J., PEG-PLA nanoparticles as carriers for nasal protein/vaccine delivery, J. Aerosol. Med., 17, 174-185 (2004)

De Campos A.M., Diebold Y., Carvahlo E.S., Sánchez A., Alonso M.J., Chitosan nanoparticles as new ocular drug delivery systems: in vitro stability, in vivo fate and cellular toxicity, Pharm. Res., 21, 803-810 (2004)

Csaba N., Sánchez A., Alonso M.J., Design and characterization of new nanoparticulate polymer blends for drug delivery, J. Biomater. Sci. Polymer Edn., 15, 1137-51  (2004)

Vila A., Gill H., McCallion O., Alonso, M.J., Transport of PLA-PEG particles across the nasal mucosa: effect of particle size and PEG coating density, J. Control. Rel., 98, 231-244 (2004)

Csaba N., Sánchez A., Fernández-Megia E., Novoa-Carballal R., Alonso M.J., Chitosan nanoparticles for the delivery of plasmid DNA: preparation and characterisation, Eur. J. Pharm. Sci., 23S, S55, PO-62 (2004)

Maestrelli F., Mura P., Alonso M.J., Formulation and characterization of triclosán submirocn emulsion and nanocapsules, J. Microencapsulation, 21, 875-864 (2004)

Garcia-Fuentes M., Martin-Pastor M., Torres D. and Alonso M. J., Application of NMR Spectroscopy to the Characterization of PEG-Stabilized Lipid Nanoparticles, Langmuir, 20, 8839-8845 (2004)

Diebold Y., de Salamanca A.E., Calonge M., Vila A., Carvalho E.L.S., de la Fuente M., Seijo B., Alonso M.J., Ocular surface in vivo tolerance to new nanoparticulate polymer systems designed for drug delivery, Invest. Ophthalmol. Vis. Sci., 46: 2048 Suppl. S (2005)

Csaba N., Caamaño P., Sánchez A., Domínguez F., Alonso M.J., PLGA: poloxamer and PLGA: poloxamine blend nanoparticles: new carriers for gene delivery, Biomacromolecules, 6, 271-8 (2005)

Prego, C., García, M., Torres, D., Alonso, M.J., Transmucosal macromolecular drug delivery, J. Control. Rel., 101, 151-162 (2005)

Vila A., Sánchez A., Évora C., Soriano I., Alonso M.J., PLA-PEG particles as nasal protein carriers: influence of the particle size, Int. J. Pharmaceut., 292, 43-52 (2005)

García-Fuentes M., Torres D., Alonso M.J., Design and Characterization of a New Drug Nanocarrier Made From Solid-Liquid Lipid Mixtures, J. Colloidal Interface Sci., 285, 590-598 (2005)

Garcia-Fuentes M., Torres D., Alonso M.J., New surface-modified lipid nanoparticles as delivery vehicles for salmon calcitonin, Int. J. Pharmaceut., 296, 122-132 (2005)

Teixeira M., Alonso M.J., Pinto M.M., Barbosa C.M., Development and characterization of PLGA nanospheres and nanocapsules containing xantone and 3-metoxy-xantone, Eur. J. Pharm. Biopharm., 59, 491-500 (2005)

Garcia-Fuentes M., Prego C., Torres D., Alonso M. J., A comparative study of the potential of solid triglyceride nanostructures coated with chitosan or poly (ethylene glycol) as carriers for oral calcitonin delivery, Eur. J. Pharm. Sci., 25, 133-143 (2005)

Aktas Y., Andrieux K., Alonso M.J., Calvo P., Gürsoy R.N., Couvreur P., Capan Y., Preparation and in vitro evaluation of chitosan nanoparticles containing a caspase inhibitor, Int. J. Pharmaceut., 298, 378-383 (2005)

Aktas Y., Yemisci M., Andrieux K., Gursoy R. N., Alonso M. J., Fernandez-Megía E., Novoa-Carballal R., Quiñoá E., Riguera R., Sargon M. F., Hamdi Celik H., Demir A. S., Atilla Hincal A., Dalkara T., Capan Y., P. Couvreur P., Development and Brain Delivery of Chitosan-PEG Nanoparticles Funcionalized with the Monoclonal Antibody OX26, Bioconjugate Chem., 16, 1503-1511 (2005)

Maestrelli F., Garcia-Fuentes M., Mura P., Alonso M. J., A new drug nanocarrier consisting of chitosan and hydoxypropylcyclodextrin, Eur. J. Pharm. Biopharm., 63, 79-86 (2006)

Prego C., Torres D., Fernandez-Megia E., Novoa-Carballal R., Quiñoá E., Alonso M.J., Chitosan-PEG nanocapsules as new carriers for oral peptide delivery.Effect of chitosan pegylation degree, J. Control Rel., 111, 299-308 (2006)

Prego C., Torres D., Alonso M.J., Chitosan nanocapsules as carriers for oral peptide delivery: Effect of chitosan molecular weight and type of salt on the in vitro behaviour and in vivo effectiveness, J. Nanosci. Nanotechnol., 6, 2921-2928 (2006)

Enrıquez de Salamanca A., Diebold Y., Calonge M., Garcıa-Vazquez C., Callejo S., Vila A., Alonso M. J., Chitosan Nanoparticles as a Potential Drug Delivery System for the Ocular Surface: Toxicity, Uptake Mechanism and In Vivo Tolerance, Invest. Ophthalmol. Vis. Sci., 47, 1416-1425 (2006)

Csaba N., Sanchez A., Alonso M.J., PLGA: Poloxamer and PLGA: Poloxamine blend nanostructures as carriers for nasal gene delivery, J. Control Rel., 113, 164-172 (2006)

Prego C., Torres D., Alonso M.J., Chitosan nanocapsules: a new carrier for nasal peptide delivery, J. Drug Del. Sci. Tech., 16, 331-337 (2006)

Prego C., Fabre M., Torres D., Alonso M. J., Efficacy and Mechanism of Action of Chitosan Nanocapsules for Oral Peptide Delivery, Pharm. Res., 23, 549-556 (2006)

Sonvico F., Cagnani A., Rossi A., Motta S., Di Bari M.T., Cavatorta F., Alonso M. J., Deriu A., Colombo P., Formation of self-organized nanoparticles by lecithin/chitosan ionic interaction, Int. J. Pharmaceut., 324, 67-73 (2006)

Cuña M., Alonso-Sande M., Remuñán-López C., Pivel J.P.,Alonso-Lebrero J.L., Alonso M.J., Development of phosphorylates glucomannan-coated chitosan nanoparticles as nanocarriers for protein delivery, J. Nanosci. Nanotechnol., 6, 2887-2895 (2006)

García Fuentes M., Trapani A., Alonso M.J., Protection of the peptide glutathione by complex formation with cyclodextrin: NMR spectroscopic análisis and stability study, Eur. J. Pharm. Biopharm., 64, 146-153 (2006)

Alonso-Sande, M., Cuña M., Remuñán-López, C., Teijeiro-Osorio, D., Alonso-Lebrero, J.L., Alonso, M.J., Formation of new glucomannan – chitosan nanoparticles and study of their ability to associate and deliver proteins, Macromolecules, 39, 4152-4158 (2006)

Santander-Ortega M.J., Csaba N., Alonso M.J., Ortega-Vinuesa J.L., Bastos-González D., Stability and physicochemical characteristics of PLGA, PLGA: poloxamer and PLGA: poloxamine blend nanoparticles. A comparative study, Colloid Surf. B-Biointerfaces, 296, 132-140 (2007)

Portero A., Teijeiro-Osorio D., Alonso M.J., Remuñán-López C., Development of chitosan sponges for buccal administration of insulin, Carbohydr. Polym., 68, 617-625 (2007)

Diebold, Y., Jarrín, M., Sáez, V., Carvalho, E.L.S., Orea, M., Calonge, M., Seijo, B., Alonso, M.J., Ocular drug delivery by liposome-chitosan nanoparticle complexes (LCS-NP), Biomaterials, 28, 1553-1564 (2007)

Krauland A.H., Alonso M.J., Chitosan/Cyclodextrin nanoparticles as macromolecular drug delivery systems, Int. J. Pharmaceut., 340, 134-142 (2007)

De la Fuente M., Seijo B., Alonso M.J., Novel hyaluronan based nanocarriers for transmucosal delivery of macromolecules, Macromol Biosci., 8, 441–450 (2008)

De la Fuente M., Seijo B., Alonso M.J., Novel hyaluronic acid-chitosan nanoparticles for ocular gene therapy, Invest. Ophthalmol. Vis. Sci., 49, 2016-2024 (2008)

De la Fuente M., Seijo B, Alonso M.J., Bioadhesive hyaluronan-chitosan nanoparticles can transport genes across the ocular mucosa and transfect ocular tissue, Gene Ther., 15, 668-676 (2008)

De la Fuente M., Seijo B., Alonso M.J., Design of novel polysaccharidic nanostructures for gene delivery, Nanotechnology, 19, 075105 (2008)

Trapani A., García-Fuentes M., Alonso M. J., Novel drug nanocarriers combining hydrophilic cyclodextrins and chitosan, Nanotechnology, 19, 185101 (2008)

Lozano M.V., Torrecilla D., Torres D., Vidal A., Domínguez F., Alonso M.J., Highly efficient system to deliver taxanes into tumor cells: docetaxel-loaded chitosan oligomer colloidal carriers, Biomacromolecules, 9, 2186-2193 (2008)

Santander-Ortega M., Alonso M.J., Insulin-Loaded PLGA nanoparticles for oral administration: An in vitro physico-chemical characterization, J. Biomed. Nanotechnol., 5, 45-53 (2009)

Teijeiro-Osorio D., Remuñán-López C., Alonso M.J., Chitosan/cyclodextrin nanoparticles can efficiently transfect the airway epithelium in vitro, J. Pharm. Biopharm., 71, 257-263 (2009)

Teijeiro-Osorio D., Remuñán-López C., Alonso M.J., New generation of hybrid Poly/Oligosaccharide nanoparticles as carriers for the nasal delivery of macromolecules, Biomacromolecules, 10, 243-249 (2009)

Oyarzun-Ampuero F.A., Brea J., Loza M.I., Torres D., Alonso M.J., Chitosan-hyaluronic acid nanoparticles loaded with heparin for the treatment of asthma, Int. J. Pharmaceut., 381,122–129 (2009)

Csaba N.,  Köping-Höggård M., Fernandez-Megia E.,  Novoa-Carballal R., Riguera R., Alonso M.J., Ionically crosslinked chitosan nanoparticles as gene delivery systems: effect of PEGylation degree on in vitro and in vivo Gene Transfer, J. Biomed. Nanotechnol. 5, 162-171 (2009)

Goycoolea F., Lollo G., Remuñán-Lopez C., Quaglia F., Alonso M.J., Chitosan-Alginate Blended Nanoparticles as Carriers for the Transmucosal Delivery of Macromolecules, Biomacromolecules , 10, 1736–1743 (2009)

Csaba N., Köping-Höggård M., Alonso M.J., Ionically crosslinked chitosan/tripolyphosphate nanoparticles for oligonucleotide and plasmid DNA delivery, Int. J. Pharmaceut., 382, 205–214 (2009)

Pinarbasli O, Aktas Y, Dalkara T, Andrieux K, Alonso MJ, Fernandez-Megia E, Novoa-Carballal R, Riguera R, Couvreur P, Capan Y., Preparation and evaluation of alpha-phenyl-n-tert-butyl nitrone (PBN)-encapsulated chitosan and PEGylated chitosan nanoparticles, Pharmazie, 7, 436-439 (2009)

Santander-Ortega M.J., Csaba N, Gonzalez L., Bastos-González D, Ortega-Vinuesa J.L., Alonso M.J., Protein-loaded PLGA: PEO blend nanoparticles: encapsulation, release and degradation characteristics, Colloid Polym Sci, 288, 141–150  (2010)

D’Angelo I., Parajó Y., Horváth A., Kéri G., La Rotonda M. I., Alonso M. J., Improved delivery of angiogenesis inhibitors from PLGA:poloxamer blend micro and nanoparticles, J. Microencapsulation, 27, 57-66 (2010)

Prego C., Paolicelli P., Díaz B., Vicente S., Sánchez A., González-Fernández A., Alonso M.J., Chitosan-based Nanoparticles for Improving Immunization against Hepatitis B Infection, Vaccine, 28, 2607–2614 (2010)

Trapani A., Lopedota A., Franco M., Cioffi N., Ieva E., Garcia-Fuentes M., Alonso M.J., A comparative study of chitosan and chitosan/cyclodextrin nanoparticles as potential carriers for the oral delivery of small peptides, Eur. J. Pharm. Biopharm., 75 , 26–32 (2010)

Contreras-Ruiz L., de la Fuente M., García Vázquez C., Sáez V., Seijo B., Alonso M.J., Calonge M., Diebold Y., Improved ocular tolerance to a topical formulation of hyaluronic acid and quitosan-based nanoparticles, Cornea, 29, 550-558 (2010)

Vicente S., Prego C., Csaba N., Alonso M.J., From single-dose vaccine delivery systems to nanovaccines, J. Drug Del. Sci. Tech., 20, 267-276 (2010)

Fernandez-Megia E., Raviña  M.,  Correa J., Sousa-Herves A., Riguera R., Alonso M.J.,  Sanchez  A., Pinto J., de la Fuente M., Core-Shell Dendriplexes with Sterically Induced Stoichiometry for Gene Delivery, Macromolecules, 43, 6953–6961 (2010)

Raviña M.,  Cubillo E., Olmeda D., Novoa-Carballal R., Fernandez-Megia E., Riguera R.,  Sánchez A., Cano A., Alonso M.J., Hyaluronic Acid / Chitosan-g-Poly(ethylene glycol) nanoparticles for gene therapy: an application for pDNA and siRNA delivery, Pharm. Res., 27, 2544-55 (2010)

D’Angelo, I., Garcia-Fuentes M., Parajó Y., Welle A., Vántus T., Horváth A., Bökönyi G., Kéri G., Alonso M.J., Nanoparticles based on PLGA:Poloxamer blends for the delivery of proangiogenic growth factors, Mol. Pharmaceutics, 7, 1724–1733 (2010)

Parajó Y., d’Angelo I., Horváth A., Vantusb T., Györgyb T., Wellec A., Garcia-Fuentes M., Alonso M.J., PLGA:poloxamer blend micro- and nanoparticles as controlled release systemsfor synthetic proangiogenic factors, Eur. J. Pharm. Sci., 41, 644-9 (2010)

Parajó Y., d’Angelo I., Welle A., Garcia-Fuentes M., Alonso M.J., Hyaluronic acid/Chitosan nanoparticles as delivery vehicles for VEGF and PDGF-BB, Drug Delivery, 17, 596–604 (2010)

Oyarzun-Ampuero F.A., Garcia-Fuentes M., Torres D., Alonso M.J., Chitosan-coated lipid nanocarriers for therapeutic applications, J. Drug Del. Sci. Tech., 20, 259-265 (2010)

Paolicelli P., Prego C., Sanchez A., Alonso M.J., Surface-modified PLGA-based nanoparticles that can efficiently associate and deliver virus-like particles, Nanomedicine, 5, 843-853 (2010)

Oyarzun-Ampuero F.A., Goycoolea F., Torres D., Alonso M.J., A new drug nanocarrier consisting of polyarginine and hyaluronic acid, Eur. J. Pharm. Biopharm., 79, 54-57 (2011)

Oyarzun-Ampuero F.A., Brea J., Loza M.I., Alonso M.J., Torres D., A potential nanomedicine consisting in heparin-loaded polysaccharide nanocarriers for the treatment of asthma, Macromol. Biosci., 12, 176–183 (2012)

De la Fuente M., Raviña M., Fernández-Megía E., Correa J., Sousa-Hervés A., Riguera R., Sánchez A., Alonso M.J., Exploring the efficiency of gallic acid-based dendrimers as carriers in gene delivery, Nanomedicine, 7, 1667-1681 (2012)

Lozano M.V., Esteban H., Brea J., Torres D., Alonso M.J., Freeze-dried polysaccharide nanocapsules: efficient vehicles for the intracellular delivery of docetaxel, J. Microencapsulation, 30,181-8 (2013)

Lozano M.V., Lollo G., Alonso-Nocelo M., Brea J., Vidal A., Torres D., Polyarginine nanocapsules: a new platform for intracellular drug delivery, J. Nanopart. Res., 15, 1515 (1-14) (2013)

Torrecilla D., Lozano M.V., Lallana E., Neissa J.I., Novoa-Carballal R., Vidal A., Fernández- Megia E., Torres D., Riguera R, Alonso M.J., Dominguez F., Anti-Tumor Efficacy of Chitosan-g-Poly(ethyleneglycol) Nanocapsules containing docetaxel: anti- TMEFF-2 functionalized nanocapsules vs non-functionalized nanocapsules”, Eur. J. Pharm. Biopharm., 83, 330–337 (2013)

Trapani A., Di Gioia S., Ditaranto N., Cioffi N., Goycoolea F., Carbone A., Garcia-Fuentes M., Conese M., Alonso M.J., Systemic heparin delivery by the pulmonary route using chitosan and glycol chitosan nanoparticles, Int. J. Pharmaceut., 447, 115– 123 (2013)

Gonzalo T.,  Lollo G., Garcia-Fuentes M.,  TorresD., Correa J., Riguera R., Fernandez-Megia E., Calvo P., Avilés P., Guillén M.J., Alonso M.J., A new potential nano-oncological therapy based on polyaminoacid nanocapsules, J. Control. Rel., 169, 10-16 (2013)

Vicente S., Díaz-Freitas B., Peleteiro M., Sánchez A., Pascual D.W., González-Fernández A., Alonso M.J., A polymer/oil based nanovaccine as a single-dose immunization approach, PLOS ONE, 8, Issue 4, e62500 (1-8) (2013)

Oyarzun-Ampuero F.A.,  Rivera G., Alonso M.J., Torres D., Hyaluronan nanocapsules as a new vehicle for intracellular drug delivery, Eur. J. Pharm. Sci., 49, 483-490 (2013)

Rivera G., Alonso M.J., Torres D., Poly-L-asparagine nanocapsules as anticancer drug delivery vehicles, Eur. J. Pharm. Biopharm., 85, 481-487 (2013)

Vicente S., Peleteiro M., Diaz-Freitas B., Sanchez A., Gonzalez-Fernandez A., Alonso M.J., Co-delivery of viral proteins and a TLR7 agonist from polysaccharide nanocapsules: A needle-free vaccination strategy, J. Control. Rel., 172, 773-781 (2013)

Alonso-Sande M.,  des Rieux A., Fievez V. Sarmento B., Delgado A., Evora C., Remuñán-López C., Preat V., Alonso M.J., Development of PLGA-mannosamine nanoparticles as oral protein carriers, Biomacromolecules, 14, 4046−4052 (2013)

Rivera-Rodriguez G., Lollo G., Montier T., Benoit J.P., Passirani C.,  Alonso M.J., Torres D., In vivo evaluation of poly-l-asparagine nanocapsules as carriers for anti-cancer drug delivery,  Int. J. Pharmaceut., 458, 83– 89 (2013)

Vicente S., Alonso M.J., Biodistribution and lymph node retention of polysaccharide-based immunostimulating nanocapsules, Vaccine, 32, 1685-92 (2014)

Lollo G., Rivera-Rodriguez G.R., Bejaud J., Tristan M., Passirani C., Benoit J.P., García-Fuentes M., Alonso M.J., Torres D., Polyglutamic acid-PEG nanocapsules as long circulating carriers for the delivery of docetaxel, Eur. J. Pharm. Biopharm., 87, 47-54 (2014)

Hervella P., Alonso-Sande M., Ledo F., Lucero M.L., Alonso M.J., Garcia-Fuentes M., PEGylated lipid nanocapsules with improved encapsulation and controlled release properties, Curr. Top.  Med. Chem., 14, 1115-23 (2014)

Vicente S., Peleteiro M.‌, Gonzalez-Aramundiz J.V.‌, Díaz-Freitas B.‌, Martínez-Pulgarín ‌S., Neissa ‌J.I., Escribano ‌J.M., Sanchez ‌A., González-Fernández ‌ A., Alonso ‌M.J., Highly versatile immunostimulating nanocapsules for specific immune potentiation, Nanomedicine, 9(15), 2273-89 (2014)

Peppas N.A. Duncan R.,.Wnek G.E., Hoffman A.S., Gao G.H., Kim S.,Lee D.S., Hadjiargyrou M., Touitou E., Ainbinder D., Mumper R., Rolland A., Niidome T., Labhasetwar V., Liu S., Zhou G., Huang Y., Xie Z., Jing X., Csaba N., Alonso M.J., Ali O., Mooney D.J., Lönn P., Dowdy S.F., Feng S., Gao J, Lee E.S., Na K., Bae Y.H., Zentner G.M., Kim H., Yoo H.S., Nakayama M., Okano T., Liao Z., Chuang E., Hsiao C., Sung H., Cabral H., Kataoka K., Nair P.R., Discher D., Mitragotri S., Highly cited research articles in Journal of Controlled Release: Commentaries and perspectives by authors, J. Control. Rel. , 190, 29–74 (2014)

Lollo G., Hervella P., Calvo P., Avilés P., Guillén M.J., García-Fuentes M., Alonso M.J., Torres D., Enhanced in vivo therapeutic efficacy of plitidepsin-loaded nanocapsules decorated with a new poly-aminoacid-PEG derivative, Int. J. Pharmaceut., 483, 212-219 (2015)

Bellido E., Hidalgo T., Lozano M.V., Guillevic M., Simon-Vazquez R., Santander-Ortega M.J., Gonzalez-Fernandez A., Serre C., Alonso M.J., Horcajada P., Heparin-engineered mesoporous iron Metal-Organic Framework Nanoparticles: towards stealth drug nanocarriers, Adv. Healthc. Mater., 4, 1246-1257 (2015)

Correia Pinto J.F., Peleteiro M., Csaba N., González-Fernández A., Alonso M.J., Multi-enveloping of particulated antigens with biopolymers and immunostimulant polynucleotides, J. Drug Del. Sci. Tech.  30, 424-434 (2015)

Correia-Pinto J.F., Csaba N., Schiller J.T., Alonso M.J., Chitosan-Poly (I:C)-PADRE based nanoparticles as delivery vehicles for synthetic peptide vaccines, Vaccines, 3, 730-750 (2015)

González Aramundiz J.V., Peleteiro M., González-Fernandez A., Alonso M.J., Csaba N., Protamine-Based Nanoparticles As New Antigen Delivery Systems, Eur. J. Pharm. Biopharm., 97, 51-59 (2015)

Beloqui A., Memvanga P.B., Coco R., Reimondez-Troitiño S., Alhouayek M., Muccioli G.G., Alonso M.J., Csaba N., De la Fuente M., Préat V., A comparative study of curcumin-loaded lipid-based nanocarriers in the treatment of inflammatory bowel disease, Colloid Surf. B-Biointerfaces, 143, 327–335 (2016)

Borrajo E., Abellan-Pose,R., Soto A., Garcia-Fuentes M., Csaba N., Alonso M.J., Vidal A., Docetaxel-loaded polyglutamic acid-PEG nanocapsules for the treatment of metastatic cancer, 238, 263-271,  J. Control. Rel. (2016)

Abellan-Pose R., Teijeiro-Valiño C., Santander-Ortega M.J., Borrajo E., Vidal A., Garcia-Fuentes M., PhD; Csaba N., Alonso M.J., Polyaminoacid nanocapsules for drug delivery to the lymphatic system: effect of the particle size, Int. J. Pharmaceut. 509, 107-117 (2016)

Alonso-Nocelo M., Abellan-Pose R., Vidal A., Abal M., Csaba N., Alonso M.J., Lopez-Lopez R., De la Fuente M., Selective interaction of PEGylated Polyglutamic Acid nanocapsules with cancer cells in a 3D model of a metastatic lymph node, Journal of Nanobiotechnology, 14:51, 1-9 (2016)

Reimondez-Troitiño S., Alcalde I., Csaba N., Íñigo Portugués A., De la Fuente M., Bech F., Riestra A. C., Merayo-Lloves J., Alonso M.J., Polymeric nanocapsules: a potential new therapy for corneal wound healing, Drug Delivery and Translational Research, 6, 708-721 (2016)

Goycoolea F. M., Brunel F., Gueddari N. E. E., Coggiola A., Lollo G., Moerschbacher B.M., Remuñán-López C., Delair T., Domard A., Alonso M.J., Physical Properties and Stability of Soft Gelled Chitosan-Based Nanoparticles, Macromol. Biosci., 16, 1873-1882 (2016)

Thwala L., Beloqui A., Tovar S., Dieguez C., Csaba N., Alonso M.J., Preat V., The interaction of protamine nanocapsules with the intestinal epithelium: a mechanistic approach, J. Control. Rel., 243,  109-120 (2016)

Lollo G., Gonzalez-Paredes A., Garcia-Fuentes M., Calvo P., Torres D., Alonso M.J., Polyarginine nanocapsules as a potential oral peptide delivery carrier, J.Pharm. Sci., 106, 611-618 (2017)

Abellan-Pose R., Rodríguez-Évora M., Vicente S., Csaba N., Évora C., Alonso M.J., Delgado A., Biodistribution of radiolabeled polyglutamic acid and PEG-polyglutamic acid nanocapsules, Eur. J. Pharm. Biopharm., 112, 155-163 (2017)

González-Aramundiz J.V., Presas E., Dalmau-Mena I., Martínez-Pulgarín S., Alonso C., Escribano J.M., Alonso M.J., Csaba N., Rational design of protamine nanocapsules as antigen delivery carriers, J. Control. Rel., 245, 62-69 (2017)

Jakubiak P., Thwala L.N., Cadete A., Préat V., Alonso M.J., Beloqui A., Csaba N., Solvent-free protamine nanocapsules as carriers for mucosal delivery of therapeutics, Eur. Polym. J. 93, 695-705 (2017)

Zhigao Niu, Tedesco E., Benetti F., Mabondzo A., MontagnerI.M., Marigo I., Gonzalez-Touceda D., Tovar S., Diéguez C., Santander-Ortega M.J., Alonso M.J., Rational design of polyarginine nanocapsules intended to help peptides overcoming intestinal barriers, J. Control. Rel., 263, 4-17 (2017)

Hongzhao Li, Robert W. Omange, Chris Czarnecki, Jorge F. Correia-Pinto, Jose Crecente-Campo, Meika Richmond, Lin Li, Nancy Schultz-Darken, Maria J. Alonso, James B. Whitney, Francis A. Plummer, Ma Luo, Mauritian Cynomolgus Macaques with M3M4 MHC Genotype Control SIVmac251 Infection, Journal of Medical Primatology 46, 137-143 (2017)

Gonzalez-Paredes A., Torres D., Alonso M.J., Polyarginine nanocapsules: A versatile nanocarrier with potential in transmucosal drug delivery, Int. J. Pharmaceut., 529, 474–485 (2017)

Teijeiro-Valiño C., Yebra-Pimentel E., Guerra-Varela J., Csaba N., Alonso M.J., Sánchez L., Assessment of the permeability and toxicity of polymeric nanocapsules using the zebrafish model, Nanomedicine, 12, 2069–2082 (2017)

Hidalgo T., Giménez-Marqués M., Bellido E., Avila J., Asensio M.C., Salles F., Lozano M. V., Guillevic M., Simón-Vázquez R., González-Fernández A., Serre C. Alonso M.J., Horcajada P., Chitosan-coated mesoporous MIL-100(Fe) nanoparticles as improved bio-compatible oral nanocarriers, Scientific Reports, 7, 43099 (2017)

Li H., Nykoluk M., Li L., Liu L.R., Omange R.W., Soule G., Schroeder L.T., Toledo N., Kashem M.A., Correia-Pinto J.F., Liang B., Schultz-Darken N., Alonso M.J., Whitney J.B., Plummer F.A., Luo M., Natural and cross-inducible anti-SIV antibodies in Mauritian cynomolgus macaques, PLoS One, 12, e0186079 (2017)

Zhigao N., Samaridou E., Jaumain E., Coëne J., Ullio G., Shrestha N., Garcia J., Durán-Lobato M., Tovar S., Santander-Ortega M.J., Victoria Lozano M.V., Arroyo-Jiménez M.M., Ramos-Membrive R., Peñuelas I., Mabondzo A., Préat V., Teixidó M., Giralt E., Alonso M.J., PEG-PGA Enveloped Octaarginine-Peptide Nanocomplexes: An OralPeptide Delivery Strategy, J. Control. Rel. 276(C), 125-139 (2018)

Peleteiro Olmedo M., Presas E., González-Aramundiz J.V., Sánchez-Correa B., Simón-Vázquez R., Csaba N., Alonso M.J., González-Fernández A., Polymeric nanocapsules for vaccine delivery: influence of the polymeric shell on the interaction with the immune system, Front. Immunol., 9:791, (doi: 10.3389/fimmu.2018.00791), (2018)

Crecente-Campo J., Lorenzo-Abalde S., Mora A., Marzoa J., Csaba N., Blanco J., González-Fernández A., Alonso M.J., Bilayer polymeric nanocapsules: A formulation approach for a thermostable and adjuvanted E. coli antigen vaccine, J. Control. Rel., 286, 20-32 (2018), https://authors.elsevier.com/a/1XPqOcI2~mBT-

Li H., Hai Y., Lim S.Y, Toledo N., Crecente-Campo J., Schalk D., Li L., Omange R.W, Gomez-Dacoba T., Liu L.R., Kashem M.A., Wan Y., Liang B., Li Q., Rakasz E., Schultz-Darken N., Alonso M.J., Plummer, F.A., Whitney J.B, Ma Luo, Mucosal antibody responses to vaccines targeting SIV protease cleavage sites or full-length Gag and Env proteins in Mauritian cynomolgus macaques, Plos One , PLoS ONE 13(8): e0202997 (https://doi.org/10.1371/journal.pone.0202997) (2018)

Thwala L.; Pan Delgado D.; Leone K.; Marigo I.; Benetti F.; Chenlo M.; Alvarez C.; Tovar S.; Dieguez C.; Csaba N.; Alonso M.J., Protamine nanocapsules as carriers for oral peptide delivery, J. Control. Rel. 291, 157–168 (2018)

Gonzalez Aramundiz J.V., Peleteiro Olmedo M., González-Fernández A., Alonso M.J., Csaba N., Protamine nanocapsules for the development of thermostable adjuvanted nanovaccines, Mol. Pharmaceutics 15, 5653−5664, (DOI: 10.1021/acs.molpharmaceut.8b00852) (2018)

Santalices I., Torres D., Lozanoc M.V., Arroyo-Jimenez M.M., Alonso M.J., Santander-Ortega M.J., Influence of the surface properties of nanocapsules on their interaction with intestinal barriers, Eur. J. Pharm. Biopharm., 133 203–213 (2018)

Crecente-Campo J., Alonso M.J., Engineering, on-demand manufacturing, and scaling-up of polymeric nanocapsules, Bioengineering & Translational Medicine,4, 38-50 (2019)

M. Ledo A., Sasso M.E., Bronte V., Marigo I., Boyde B.J., Garcia-Fuentes M., Alonso M.J., Co-delivery of RNAi and chemokine by polyarginine nanocapsules enables the modulation of myeloid-derived suppressor cells, J. Control. Rel., 295, 60–73 (2019)

Teijeiro-Valiño C, Novoa-Carballal R., Borrajo E., Vidal A., Alonso-Nocelo M., de la Fuente Freire M., Lopez-Casase P.P., Hidalgo M., Csaba N., Alonso M.J., A multifunctional drug nanocarrier for efficient anticancer therapy, J. Control. Rel., 294, 154–164 (2019)

Cordeiro A.S, Crecente-Campo J., L. Bouzo B., González, S.F. de la Fuente M., Alonso M.J., Engineering polymeric nanocapsules for an efficient drainage and biodistribution in the lymphatic system, J.Drug Target., 27(5-6):646-658 (2019)

Dacoba T.G., Omange R.W., Li H., Crecente-Campo J., Luo M., Alonso M.J., Polysaccharide nanoparticles can efficiently modulate the immune response against an HIV peptide antigen, ACS Nano, 13, 4947–4959 (2019) (DOI: 10.1021/acsnano.8b07662).

Štakaka I., Cadete A., Surikutchi B.T., Abuzaid H., Bradshaw T.D., Alonso M.J., Marlow M., A novel low molecular weight nanocomposite hydrogel formulation for intra-tumoural delivery of anti-cancer drugs, Int. J. Pharmaceut., 565, 151–161 (2019)

Molina-Crespo A., Ana Cadete, David Sarrio, Gamez Chiachio M., Martinez L., Chao K., Olivera A., Gonella A., Diaz A., Palacios J., Dhal P.K., Besev M., Rodriguez-Serrano M., García-Bermejo M.L., Triviño J.C., Cano A., Garcia-Fuentes M., Herzberg O., Torres D., Alonso M.J., Moreno-Bueno G., Intracellular delivery of an antibody targeting Gasdermin-B reduces HER2 breast cancer aggressiveness, Clinical Cancer Research (Doi: 10.1158/1078-0432.CCR-18-2381) (2019)

Crecente-Campo J., Guerra-Varela J., Peleteiro M., Gutiérrez-Lovera C., Fernández-Mariño I., Diéguez-Docampo A., González-Fernández A., Sánchez L., Alonso M.J., The size and composition of polymeric nanocapsules dictate their interaction with macrophages and biodistribution in the zebrafish model, J. Control. Rel 308, 98-108 (2019)

Reimondez-Troitiño S., González-Aramundiz J.V., Ruiz-Bañobrea J., López-López R., Alonso M.J., Csaba N., de la Fuente M., Versatile protamine nanocapsules to restore miR-145 levels and interferetumor growth in colorectal cancer cells, Eur. J. Pharm. Biopharm, 142, 449-459 (2019)

Cadete A., Olivera A., Besev M., Dhal P.K., Gonçalves L., Almeida A.J., Bastiat G., Benoit J.P., de la Fuente M., Garcia-Fuentes M., Alonso M.J., Torres D., Self-assembled hyaluronan nanocapsules for the intracellular delivery of anticancer drugs, Scientific Reports, 9, Article number: 11565 (2019)

Crecente-Campo J., Virgilio T., Morone D., Cristina Calviño-SampedroC., Fernandez-Mariño D., Olivera A., Varela-Calviño R., Gonzalez S.F., Alonso M.J., Design of polymeric nanocapsules to improve their lympho-targeting capacity, Nanomedicine, 119657 (2020)

Samaridou E., Kalamidas N., Santalices I., Crecente-Campo J., Alonso M.J., Tuning the PEG surface density of the PEG-PGA enveloped Octaarginine-peptide Nanocomplexes., Drug Deliv. Transl. Res., 10, 241-258, (2020). Doi: 10.1007/s13346-019-00678-3.

Samaridou E., Walgrave H., Salta E., Moreira Álvarez D., Castro-López V., Loza M., Alonso M.J., Nose-to-brain delivery of enveloped RNA – cell permeating peptide nanocomplexes for the treatment of neurodegenerative diseases, Biomaterials, 230, 119657 (2020), https://doi.org/10.1016/j.biomaterials.2019.119657

Klein M., Menta M., G. Dacoba T., Crecente-Campo J., Alonso M.J., Dupin D., Loinaz I., Grassl B., Séby F., Advanced nanomedicine characterization by DLS and AF4-UV-MALS: Application to a HIV nanovaccine, Journal of Pharmaceutical and Biomedical Analysis, 179, 113017 (2020), https://doi.org/10.1016/j.jpba.2019.113017

G. Dacoba T., Ruiz-Gatón L., Benito A., Klein M., Dupin S., Luo M., Menta M., Teijeiro-Osorio D., Loinaz I., Alonso M.J., Crecente-Campo J., Technological challenges in the preclinical development of an HIV nanovaccine candidate, Drug Delivery and Translational Research (2020) (https://doi.org/10.1007/s13346-020-00721-8)

M. Ledo A., Senra A., Rilo-Alvarez H., Borrajo E., Vidal A., Alonso M.J., Garcia-Fuentes M., mRNA-activated matrices encoding transcription factors as primers of cell differentiation in tissue engineering, Biomaterials (2020) (Accepted) https://doi.org/10.1016/j.biomaterials.2020.120016

Storozhylova N., Crecente-Campo J., Cabaleiro D., Lugo L., Dussouy C., Simoes S., Monteiro M., Grandjean C., Alonso M.J., An in Situ Hyaluronic Acid-Fibrin Hydrogel Containing Drug-Loaded Nanocapsules for Intra-Articular Treatment of Inflammatory Joint Diseases, Regen. Eng. Transl. Med. (2020). https://doi.org/10.1007/s40883-020-00154-2

M.Ledo, A., H. Vining K., Alonso M.J., Garcia-Fuentes M., Mooney D. J., Extracellular matrix mechanics regulate transfection and SOX9-directed differentiation of mesenchymal stem cells, Acta Biomaterialia, 110, 153-163 (2020)

Alonso, M.J. My one-year perspective as editor-in-chief of DDTR. Drug Deliv. and Transl. Res. (2020). https://doi.org/10.1007/s13346-020-00767-8

Dacoba TG, Anfray C, Mainini F, Allavena P, Alonso MJ, Torres Andón F and Crecente-Campo J (2020) Arginine-Based Poly(I:C)-Loaded Nanocomplexes for the Polarization of Macrophages Toward M1-Antitumoral Effectors. Front. Immunol. 11:1412. doi: 10.3389/fimmu.2020.01412

Del Río-Sancho S., Pan Delgado D., de la Fuente G., García-Caballero T., Taboada-Suárez A., Csaba N., Bao-Varela C., Alonso M.J., Laser-induced transient skin disruption to enhance cutaneous drug delivery, Eur. J. Pharm. Biopharm, 156, 165-175 (2020). https://doi.org/10.1016/j.ejpb.2020.08.027

Vázquez-Ucha J.C., Martínez-Guitián M., Lasarte-Monterrubio C., Conde-Pérez K., Arca-Suárez J., Álvarez-Fraga L., Pérez A., Crecente-Campo J., Alonso M.J., Bou G., Poza M., Beceiro A., Syzygium aromaticum (clove) and Thymus zygis (thyme) essential oils increase susceptibility to colistin in the nosocomial pathogens Acinetobacter baumannii and Klebsiella pneumoniae, Biomedicine & Pharmacotherapy 130, 110606 (2020).https://doi.org/10.1016/j.biopha.2020.110606 

Nikki P. L. Toledo, Hongzhao Li, Robert W. Omange, Tamara G. Dacoba, Jose Crecente-Campo, Dane Schalk, Mohammad A. Kashem,Eva Rakasz , Nancy Schultz-Darken, Qingsheng Li, James B. Whitney, Maria J. Alonso, Francis A. Plummer, Ma Luo, Cervico-Vaginal Inflammatory Cytokine and Chemokine Responses to Two Different SIV Immunogens, Front. Immunol. 11, 1935 (2020). https://doi.org/10.3389/fimmu.2020.01935

Li H., Omange R.W. Liang B., Toledo N., Hai Y., Liu L.R., Schalk D., Crecente-Campo J., Dacoba T.G., Lambe A.B., Lim S.-Y., Li L., Kashem M.A., Wan Y., Correia-Pinto J.F., Seaman M.S., Liu X.-Q., Balshaw R.F., Li Q., Schultz-Darken N., Alonso M.J., Plummer F.A., Whitney J.B., Luo M., Vaccine targeting SIVmac251 protease cleavage sites protects macaques against vaginal infection, J. Clin. Invest. 130(12):6429-6442 (2020)

Cordeiro AS, Farsakoglu Y, Crecente-Campo J, de la Fuente M, González SF, Alonso MJ. Carboxymethyl-β-glucan/chitosan nanoparticles: new thermostable and efficient carriers for antigen delivery. Drug Deliv Transl Res. 2021 Apr 1. doi: 10.1007/s13346-021-00968-9. Epub ahead of print. PMID: 33797035.

Santalices, I., Vázquez-Vázquez, C., Santander-Ortega, M.J. et al. A nanoemulsion/micelles mixed nanosystem for the oral administration of hydrophobically modified insulin. Drug Deliv. and Transl. Res. (2021). https://doi.org/10.1007/s13346-021-00920-x.

Bouzo B.L., Lores S., Alijas S., Alonso M.J., Conejos-Sánchez I., de la Fuente M. Sphingomyelin nanosystems loaded with uroguanylin and etoposide for treating metastatic colorectal cancer, Scientific Reports, 11, 1, Article number 17213 (2021)

Borrajo, M.L., Alonso, M.J., Using nanotechnology to deliver biomolecules from nose to brain — peptides, proteins, monoclonal antibodies and RNA, Drug Deliv. and Transl. Res. (2021)

Berrecoso G., Crecente‐Campo J., Alonso M.J., Quantification of the actual composition of polymeric nanocapsules: a quality control analysis, Drug Deliv. and Transl. Res. (2022)

Lundquist P., Khodus G., Zhigao N., Thwala L.N., McCartney F., Simoff I., Andersson E., Beloqui A., Mabondzo A., Robla S., Webb D.L., Hellström P.M., Keita A.V., Sima E., Csaba N., Sundbom M., Preat V., Brayden D.J., Alonso M.J., Artursson P., Barriers to the Intestinal Absorption of Four Insulin-Loaded Arginine-Rich Nanoparticles in Human and Rat, ACS Nano 2022 (In Press)

Bhanu Teja Surikutchi, Rebeca Obenza-Otero, Emanuele Russo, Mischa Zelzer, Irene Golán Cancela, José A. Costoya, José Crecente Campo, Maria José Alonso, Maria Marlow, Development of a nanocapsule-loaded hydrogel for drug delivery for intraperitoneal administration, Int. J. Pharmaceut., 622, 121828 (2022)

Goldberg, M., Manzi, A., Conway, P. et al. A nanoengineered topical transmucosal cisplatin delivery system induces anti-tumor response in animal models and patients with oral cancer. Nat Commun 13, 4829 (2022).

Fernández-Mariño I, Anfray C, Crecente-Campo J, et al. Mannose-modified hyaluronic acid nanocapsules for the targeting of tumor associated macrophages, Drug Deliv. and Transl. Res. (2022) (ACCEPTED)

Anthiya S., Oztürk S.C., Yanik H., Tavukcuoglu E., Sahin A., Datta D., Charisse K., Moreira Alvarez D., Loza M.I., Calvo A., Sulheim E., Loevenich S., Klinkenberg G., Schmid R., Manoharan M., Esendagli G., Alonso M.J., Targeted siRNA lipid nanoparticles for the treatment of KRAS-mutant tumors, J. Control. Rel. 357, 67–83 (2023)

Mali A., Franci G., Zannella C., Chianese A., Anthiya S., López-Estévez A.M., Monti A., De Filippis A., Doti N., Alonso M.J., Galdiero M., Antiviral Peptides Delivered by Chitosan-Based Nanoparticles to Neutralize SARS-CoV-2 and HCoV-OC43, Pharmaceutics, 15, 1621 (2023)

Abbadessa A., Nuñez Bernal P., Buttitta G., Ronca A., D’Amora U, Zihlmann C., Stiefel N., Ambrosio L., Malda J., Levato R., Crecente-Campo J., Alonso M.J., Biofunctionalization of 3D printed collagen with bevacizumab-loaded microparticles targeting pathological angiogénesis, J. Control. Rel., 360 747–758 (2023)

Berrecoso, G., Bravo, S.B., Arriaga, I, Abrescia N., Crecente-Campo J., Alonso M.J., Controlling the protein corona of polymeric nanocapsules: effect of polymer shell on protein adsorption, Drug Deliv. and Transl. Res., 14, 918-933 (2024)

Esteban, I.; Pastor-Quiñones, C.; Usero, L.; Aurrecoechea, E.; Franceschini, L.; Esprit, A.; Gelpí, J.L.; Martínez-Jiménez, F.; López-Bigas, N.; Breckpot, K.; et al. Assessment of Human SARS CoV-2-Specific T-Cell Responses Elicited In Vitro by New Computationally Designed mRNA Immunogens (COVARNA). Vaccines, 12, 15. (2024)

López Estévez A.M., Lapuhs P., Piñeiro Alonso L., Alonso M.J., Personalized cancer nanomedicine: Overcoming biological barriers for intracellular delivery of biopharmaceuticals, Adv. Materials, 36, 2309355 (2024)

Laura Marcos-Villar, Beatriz Perdiguero, Shubaash Anthiya, Mireya L. Borrajo, Gustavo Lou, Lorenzo Franceschini, Ignasi Esteban, Pedro J. Sánchez-Cordón, Carmen Zamora, Carlos Óscar S. Sorzano, Luis Jordá, Laia Codó, Josep L. Gelpí, Marta Sisteré-Oró, Andreas Meyerhans, Kris Thielemans, Francisco Martínez-Jiménez, Nuria López-Vigas, Felipe García, María J. Alonso, Montserrat Plana, Mariano Esteban,Carmen Elena Gómez, Modulating the immune response to SARS-CoV-2 by different nanocarriers delivering an mRNA expressing trimeric RBD of the spike protein: COVARNA Consortium, npj Vaccines 9, 53 (2024)

Mireya L. Borrajo, Gustavo Lou, Shubaash Anthiya, Philipp Lapuhs, David Moreira Álvarez, Araceli Tobío, María Isabel Loza, Anxo Vidal, María José Alonso, Nanoemulsions and nanocapsules as carriers for the development of intranasal mRNA vaccines, Drug Deliv. and Transl. Res. 14, 2046-2061, (2024)

Ana M. López-Estévez, Y. Zhang, María Medel, Iker Arriaga, Lucía Sanjurjo, Cristian Huck-Iriart, Nicola G. A. Abrescia, María J. Vicent, Defang Ouyang, Dolores Torres, María José Alonso, Engineering hyaluronic acid-based nanoassemblies for monoclonal antibody delivery – design, characterization, and biological insights, Nano Res., 17, 9111–9125, (2024)

Ana María López Estévez, Lucía Sanjurjo Bouza, Ángela Turrero, Iker Arriaga Saez, Nicola G.A. Abrescia, Ana Poveda, Jesús Jiménez-Barbero, Anxo Vidal, Dolores Torres, Maria Jose Alonso, Nanotechnology-assisted intracellular delivery of antibody as a precision therapy approach for KRAS-driven tumors, J. Control. Rel., 373, 277-292 (2024)

Laura Marcos-Villar, Beatriz Perdiguero, María López-Bravo, Carmen Zamora, Laura Sin, Enrique Álvarez, Carlos Óscar S. Sorzano, Pedro J. Sánchez-Cordón, José M. Casasnovas , David Astorgano, Juan García-Arriaza, Shubaash Anthiya, Mireya L. Borrajo, Gustavo Lou, Belén Cuesta, Lorenzo Franceschini, Josep L. Gelpí, Kris Thielemans , Marta Sisteré-Orók, Andreas Meyerhans, Felipe García, Ignasi Estebann, Núria López-Bigas, Montserrat Plana, María J. Alonso, Mariano Estebana, Carmen Elena GómezHeterologous mRNA/MVA delivering trimeric-RBD as effective vaccination regimen against SARS-CoV-2: COVARNA Consortium, Emerging Microbes & Infections, 13, 2387906 (15 pages) (2024)

L. Borrajo M., Quijano A., Lapuhs P., Rodriguez-Perez A.I., Anthiya S., Labandeira-Garcia J.L., Valenzuela R., Alonso M.J., Ionizable nanoemulsions for RNA delivery into the central nervous system-importance of diffusivity, J. Control. Rel., 372, 295-303 (2024)

Durán‐Lobato M., Tovar S., de Oliveira Diz T., Chenlo M., V. Álvarez C., Alonso M.J., Formulation of protein-loaded nanoparticles via freeze-drying, Drug Delivery and Translational Research, 14, 3640–3653 (2024)

López-Estévez A.m., Carrascal-Miniño A., Torres D., Alonso M.J., de Rosales R. T. M., Pellico J., Biodistribution of 89Zr-Radiolabeled Nanoassemblies for Monoclonal Antibody Delivery Revealed through In Vivo PET Imaging, ACS Omega (2025) https://doi.org/10.1021/acsomega.4c09823

Laura Pineiro-Alonso, Inés Rubio-Prego, Alexandra Lobyntseva, Eva González-Freire, Robert Langer, María José Alonso, Nanomedicine for targeting brain Neurodegeneration: Critical barriers and circadian rhythm Considerations, Advanced Drug Delivery Reviews, Volume 222, 2025, 115606, ISSN 0169-409X, https://doi.org/10.1016/j.addr.2025.115606

VII. a. Research Grants

“Design and optimization of new dosage forms of drugs for the oftalmic and intraarticular administration” financed by the University of Santiago de Compostela, Spain (1989)
Principal Investigator: J.L. Vila Jato

“Biodegradable systems for the controlled macromolecule delivery” financed by the Spanish Ministry of Science and Technology, Spain (1991-93)
Principal Investigator: M.J. Alonso

“Design of microencapsulated systems for vaccine administration” financed by the Xunta de Galicia, Spain (1994-95)
Principal Investigator: B. Seijo

“Development and optimization of biodegradable microspheres for the controlled delivery of therapeutic and antigenic proteins” financed by the Spanish Commission of Science and Technology, Spain (1994-96)
Principal Investigator: M.J. Alonso

“Stabilizing tetanus toxoid for encapsulation in poly(lactic/glycolic) acid  microspheres” financed by the World Health Organization (OMS) (1994-96)
Principal Investigator: M.J. Alonso

“Development of New Controlled Release Vaccine Delivery Systems” financed by the OTAN (1995-97)
Principal Investigator: M.J. Alonso

“Chemically Modified Immunomodulators Associated to Colloidal Carriers for Cancer Therapy” financed by the Praxis XXI Programme (1997-99)
Principal Investigator: M.J. Alonso

“Development of coloidal systems (liposomes and nanospheres) for the oral administration of vaccines” financed by the Xunta de Galicia, Spain (1996-97)
Principal Investigator: B. Seijo

“Development of nanoparticles as macromolecular carriers for mucosal administration” financed by the Spanish Commission for Sciences and Technology, Spain (1997-2000)
Principal Investigator: M.J. Alonso

“Targeting of immunomodulators to the gut associated lymphoid tissue through the use of colloidal systems” financed by the Spanish Commission for Sciences and Technology, Spain (2000-2001)
Principal Investigator: M.J. Alonso

“Design and evaluation of new lipid systems for improving the oral absorption of peptides” financed by the Xunta de Galicia, Spain (2000-2001)
Principal Investigator: M.J. Alonso

“Design and evaluation of new lipid systems for improving the oral absorption of peptides. Aplication to sCT” financed by the Spanish Commission for Sciences and Technology, Spain (2000-2002)
Principal Investigator: M.J. Alonso

“Design of colloidal carriers for DNA delivery” financed by the Xunta de Galicia, Spain (2000-2002)
Principal Investigator: M.J. Alonso

“Evaluation of new colloidal biodegradable systems for the transport of drugs across the ocular mucosa” financed by the Spanish Commission for Sciences and Technology, Spain (2000-2002)
Principal Investigator: M.J. Alonso

“Design of colloidal systems targeted to the GALT” financed by the Xunta de Galicia, Spain (2003-2005)
Principal Investigator: M.J. Alonso

“New strategies for the treatment of pulmonary diseases: biodegradable nanoparticles” financed by the Ministry of Science and Technology, Spain (2003-2005)
Principal Investigator: M.J. Alonso

“New therapeutic strategies for the treatment of tumors: targeted nanoparticles” financed by the Ministry of Science and Technology, Spain (2004-2006)
Principal Investigator: M.J. Alonso

“Development of nanoparticles for plasmid release in the ocular mucosa” financed by Xunta de Galicia, Spain (2005-2007)
Principal Investigator: M.J. Alonso

“Bioreactive composite scaffold design for improved vascular conexión of tissue-engineered products” financed by the European Commission – FP6 (2005-2008)
Principal Investigator: M.J. Alonso

“Nanotechnologies for bio-inspired polysaccharides: biological “decoys” designed as knowledge-based multifunctional materials” financed by the European Commission-FP6 (2005-2008)
Principal Investigator: M.J. Alonso

“Nanotecnologies in biomedicine” Consolider-Ingenio 2010 Programme, financed by the Spanish Ministry of Science and Technology, Spain (2006-2010)
Principal Investigator and WP leader: M.J. Alonso

“Biopolymer-Based Nanoparticle Smart Drug Delivery Systems and their Biopharmaceutical Application by Oral Administration”(BioNanoSmart_DDS) financed by the European Commission- FP7 (2007-2010).
Principal Investigator and WP leader: M.J. Alonso

“Surface-modified nanostructures as carriers for nasal vaccine delivery” financed by the Grand Challenges in Global Health Program of the “Bill and Melinda Gates Foundation” (2005-2010).
Coordinator of Consortium and Principal Investigator: M.J. Alonso

“Nanovaccines: Design of polymeric nanostructures for vaccination” financed by the Ministry of Science and Innovation, Spain (2008-2011).
Coordinator of Consortium and Principal Investigator: M.J. Alonso

“Lymphonanocarriers for the treatment of metastatic cancer”, EuroNanoMed ERA-NET- FP7, EUROPEAN COMMISSION, Spanish Ministry of Science and Innovation (2010-2013).
Coordinator of Consortium and Principal Investigator: M.J. Alonso

“Support for Cancer Researchers”, financed by the Asociación Española contra el Cáncer (AECC Foundation) (2010-2014).
Principal Investigator: M.J. Alonso

“Study of the interaction of nanomaterials with antigens: a systematic approach for nanovaccine design”, Spanish Ministry of Science and Innovation (2012-2014)
Coordinator of Consortium and Principal Investigator: M.J. Alonso

“New oral nanomedicines: transporting therapeutic macromolecules across the intestinal barrier” (TRANSINT), EUROPEAN COMMISSION – FP7 (NMP Large scale integrating collaborative Project) (2012-2017)
Coordinator of Consortium and Principal Investigator: M.J. Alonso

“Competitive Reference Groups”, financed by the Consellería de Educación, Xunta de Galicia, Spain, (2013-2016)
Principal Investigator: M.J. Alonso

“NANOFAR Erasmus Mundus Joint Doctorate in Nanomedicine and Pharmaceutical Innovation”, EMJD NanoFar-ref.520170-1-2011-1-FR-ERA MUNDUS-EMJD, EUROPEAN COMMISSION (2013-2017)
Principal Investigator and member of the project Board: M.J. Alonso

“Nano Inmuno Chemotherapy” (NICHE), EuroNanoMed ERA-NET- FP7, EUROPEAN COMMISSION –CIBER BBN, Spain (2014-2017)
Principal Investigator: M.J. Alonso

“A Novel HIV-1 Vaccine Targeting the 12 protease Cleavage Sites”, financed by the National Institutes of Health, (2014-2017)
Principal Investigator: M.J. Alonso

“Design and development of advanced NAnomedicines to overcome Biological BArriers and to treat severe diseases” (NABBA), EUROPEAN COMMISSION–H2020-MSCA-ITN-2014 (2015-2019)
Principal Investigator: M.J. Alonso

“A Pilot Plant for the Production of Polymer based Nanopharmaceuticals in Compliance with GMP” (NANOPILOTS), Financed by the EUROPEAN COMMISSION–H2020-NMP-PILOTS-2014 (2015-2019)
Principal Investigator: M.J. Alonso

“New approaches for diagnosis, treatment and regeneration of the pathology of the ocular surface” (SURFeye), financed by the Spanish Ministry of Economy and Competitivity (2014-2016)
Principal Investigator: M.J. Alonso

“Application of nanotechnology for the development of vaccines for autoimmunity”, financed by the Spanish Ministry of Economy and Competitivity (2015-2018)
Principal Investigator: M.J. Alonso

“Sequential combination of chemo-immunotherapy with trabectedin and functionalized immunomodulatory nanostructures to optimally target Tumor-Associated Macrophages in vivo”, financed by the Worldwide Cancer Research Organization (2015-2018)
Principal Investigator: M.J. Alonso

“Brain-Specific, Modular and Active RNA Therapeutics” B-SMART, EUROPEAN COMMISSION– H2020-NMBP-2016-2017 (2016-2021)
Principal Investigator: M.J. Alonso

“Development of customized treatments for glaucoma. Emphasis on child and elderly populations” (GLAUKUS) financed by the Spanish Ministry of Economy and Competitivity (2016-2019)
Principal Investigator: M.J. Alonso

“Innovative solutions for the treatment of dry eye combined with eye pain” (SEKEYE) financed by the Spanish Ministry of Economy and Competitivity (2016-2019)
Principal Investigator: M.J. Alonso

“Consolidation and structuration 2017 GRC GI-1643 – Nanotecnologies applied to the design of drug delivery systems” (NANOBIOFAR) / REF: ED431C 2017/09, Xunta de Galicia, Consellería de Cultura, Educación e Ordenación Universitaria (2017-2020)
Principal Investigator: Dolores Torres López

“A multifunctional nanomedicine for the treatment of metastatic cancer” (ONCOMETA) – IGNICIA 2017, Axencia Galega de Innovación, Xunta de Galicia-IGNICIA Programme 2017 (2017-2019)
Principal Investigator: M.J. Alonso

“Enhancing the effect of Cancer Immunotherapythrough the Re-education of Tumor Associated Macrophages”, Research Grants for AECC researcher in the field of oncology Spanish Asociation of Cancer-AECC (2018-2020)
Principal Investigator: M.J. Alonso

“Nano-Immunotherapy: Intracellular Targeting Of Cancer Cells And Tams”, Spanish Ministry of Economy and Competitivity, EuroNanoMedIII – ERA NET (PCIN-2017-129/ AEI) (2017-2020)
Principal Investigator: Mª José Alonso (Coordinator)

“Integrated Nano-Immunotherapies Targeted To Intracellular Proteins Relevant In Cancer”, Spanish Ministry of Economy and Competitivity (SAF2017-86634-R), (2018-2020)
Principal Investigator: Mª José Alonso

“Meniscal functionalised scaffold to prevent knee Osteoarthritis onset after meniscectomy” (MEFISTO), EUROPEAN COMMISSION– H2020-NMBP-TR-IND-2018-2020- Grant N. 814444 (2019-2022)
Principal Investigator: Mª José Alonso (Partner)

“Preclinical development of innovative mRNA/MVAvaccines against SARS-CoV2” (COVARNA), Instituto Salud Carlos III (2020)
Principal Investigator: Mª José Alonso (Partner)
Coordinator: Felipe García

“2^2-INTRATARGET: Nanocarriers to deliver antibodies towards intracellular targets in cancer cells/TAMs at primary/metastatic sites”, Instituto Salud Carlos III, EuroNanoMedIII – ERA NET (AC20/00028) (2020-2023)
Principal Investigator: Mª José Alonso (Coordinator)

“siRNA-based combined nano-immunotherapies applied to the treatment of lung cancer” (ONCO-siRNA). AEI-Agencia Estatal de Investigación (PID2020-119368RB-I002021-2024)
Principal Investigator: Mª José Alonso

“Proof-of-concept study of a new oncological nanotherapy consisting of a monoclonal antibody directed at intracellular targets”. AEI-Agencia Estatal de Investigación (PDC2021-120929-I00) (2021-2022)
Principal Investigator: Mª José Alonso

“Early molecular nanoDIAGnostics of Brain tumors using Immune-PET (DIAGBI)”, AEI-Agencia Estatal de Investigación (PLEC2021-008034) (2021-2023)
Principal Investigator: Pablo Aguiar and Mª José Alonso

“Development of nanotherapies for prevention and treatment of COVID-19 (Nanodecov)-CONECTA COVID Programme, AXENCIA GALEGA DE INNOVACION (GAIN), Xunta de Galicia (IN852D 2021/16) (2021-2023)
Principal Investigator: Mª José Alonso

“Nanovectors for direct, loco-regional and controlled intravenous administration of antitumor drugs. Strategies to minimize adverse effects and maximize therapeutic response. ONCOLIBERYX, Ministry of Science and Innovation (CPP2021-008362) (2022-2024)
Principal Investigator: Mª José Alonso

“Repositioning of cytotoxic compounds from marine organisms for intratumoral immunotherapy” (RECYTSEA), Ministry of Science and Innovation (PLEC2022-009298) (2023-2025)
Principal Investigator: Mª José Alonso

“Innovative Nasal Vaccines to prevent pathogen colonization and infection in the upperrespiratory tract” (NOSEVAC), EUROPEAN COMMISSION (HORIZON-HLTH-2022- Ref. 101080528 — NOSEVAC)- (2023-2028)
Principal Investigator: Noemi Csaba and Mª José Alonso

“Targeting Circadian Clock Dysfunction in Alzheimer’s Disease” TClock4AD, EUROPEAN COMMISSION (HORIZON-MSCA-2021-DN-01- Ref. 101072895) (2023-2027)
Principal Investigator: Mª José Alonso

“Nanotechnology to Advance Cellular Therapies: novel mRNA nanocarriers for T-cell reprogramming” (MCIU/AEI-Agencia Estatal de Investigación and FSE+// PID2023-150416OB-I00) (2024-2027)
Principal Investigator: Mª José Alonso

VII. b. Research contracts with companies

“Encapsulated ionic polymers and resins as ophthalmic dosage forms”, financed by Allergan Laboratories, S.A.E., (1988-1990).
Principal Investigator: J.L. Vila Jato

“Development of new coloidal polymeric systems for ocular administration”, financed by Cusi Laboratories, S.A. (1991-1993).
Principal Investigator: J.L. Vila Jato

” Development of a microencapsulated cefuroxime axetile”, financed by Glaxo Laboratories, S.A. (1993-1994).
Principal Investigator: M. J. Alonso

“Inmunomodulación del rechazo del transplante de cornea mediante nanocapsulas cargadas con cyclosporina A”, financed by Sandoz Laboratories, S.A. (1993-1994).
Principal Investigator: J.C. Pastor

“Desarrollo de sistemas ultradisperso de uso oftálmico”, financed by Cusi Laboratories, S.A.
(1995). Principal Investigator: M. J. Alonso

“Desarrollo de nanopartículas para la vehiculización de macromoléculas a través de las superficies mucosas”, financed by Pierre Fabre Ibérica Laboratories, S.A. (1997-2000). Principal Investigator: M. J. Alonso

“Diseño de sistemas coloidales dirigidos al tejido linfoide asociado a la mucosa intestinal: aplicación al transporte de fármacos inmunomoduladores” financed by IFC, S.A. (2000-2001).
Principal Investigator: M. J. Alonso

“Diseño y evaluación de sistemas lipídicos destinados a mejorar la absorción sistémica de fármacos peptídicos: aplicación a la calcitonina ”, financed by Almirall Prodesfarma (2001-2003).
Principal Investigator: M. J. Alonso

“Development and optimization of PEGylated nanoparticles for nasal drug delivery”, financed by Bespak Europe Ltd. (2001-2002).
Principal Investigator: M. J. Alonso

“Desarrollo de micropartículas de derivados polioxietileno para la liberación controlada de fármacos”, financed by Italfármaco S.A. (2003-2004).
Principal Investigator: M. J. Alonso

“Scientific supervision of a USC-based drug delivery unit”, financed by Advanced in Vitro Cell Technologies (2003-2013).
Principal Investigator: M. J. Alonso

“Acuerdo Marco para la implantación y desarrollo de la Unidad Empresarial ADVANCELL GALICIA, Unidad de Drug Delivery”, financed by Advanced In Vitro Cell Technologies (Advancell) (2004-2013).
Principal Investigator: M.J. Alonso

“Nanofarma-Cenit Project”, financed by Pharmamar (2006-2010)
Principal Investigator: M.J. Alonso

“CEYEC Project”, financed by Faes Farma and Ministry of Science and Innovation, Spain
(2010-2012).
Principal Investigator: M.J. Alonso

”Cooperation Agreement on Post-Doctoral Project”, financed by NovoNordisk (2011-2012). Principal Investigator: M.J. Alonso

“COLIVAC-Innterconecta Project, Financed by Nanogap S.A. (2013-15)
Principal Investigator: M.J. Alonso

“Material Transfer Agreement”, Financed by Novonordisk (2015-2016)
Principal Investigator: M.J. Alonso

“Collaborative research agreement in the field of potential aplication of nanotechnologies in specific drug delivery”, Financed by Novartis Consumer Health, S.A.- a GSK Consumer Healthcare Company (2016-2017) (2017-2019)
Principal Investigator: M.J. Alonso

“Tech Transfer Contract”, Financed by Industrial Farmaceútica Cantabria S.A (Cantabria Labs) (2018-2020)
Principal Investigator: M.J. Alonso

“Collaboration agreement for valorisation between HIPRA and USC”, Hipra Scientific S.L.U, and Laboratorios Hipra S.A. (2021)
Principal Investigator: M.J. Alonso

“Development of nanoparticles for delivery of nucleic acid cargo via the nose-to-brain route”, Financed by ELI LILLY and Company (2020-2023)
Principal Investigator: M.J. Alonso

“Biocorona Research Project”, Financed by ELI LILLY and Company (2024-2027)
Principal Investigator: M.J. Alonso

“Fibrin hydrogels for intraocular delivery of dexamethasone”, Financed by Farmamix Vision S.L. (2024-2025)
Principal Investigator: M.J. Alonso

XI. a. Awards granted by scientific organizations and companies

First Prize LICONSA granted by the Chemo Foundation for the Development and Research and sponsored by Liconsa, liberación Controlada de Sustancias Activas, S.A., for the best work on drug delivery: “Nanopartículas de quitosano diseñadas para mejorar el transporte de moléculas activas a través de superficies mucosas”, 1992. Authors: Alonso M.J., Remuñán C., Fernández-Urrusuno R., Vila-Jato, J.L.

EURAND Award granted by the company Eurand to the best research work on oral administration of drugs: “Nanopartículas de quitosano-glucomanano: nuevos transportadores coloidales para la administración de proteínas”, 2002. Authors: Remuñán-López C., Alonso-Sande M., Cuña M., Alonso-Lebrero J.L., Pivel J.P., Alonso M.J.

“CRS-CAPSUGEL” Award to the best research work presented at the 30th Conference of the Controlled Release Society, Glasgow “Chitosan and chitosan-PEG nanocapsules: new carriers for improving the oral absorption of calcitonin”, 2003. Authors: Prego C., Fernández-Megia E., Novoa-Carballal R., Quiñoá E., Torres D., Alonso M.J.

First Prize of the “EUROPEAN CHITIN SOCIETY” to the best research work presented at the 10th International Conference on Chitin and Chitosan, Montpellier (Francia) “Assessment of Chitosan/Cyclodextrin Nanoparticles in Calu-3 Cells”, 2006. Authors: Teijeiro-Osorio D., Remuñán-López C., and Alonso M.J.

“SERenidade” Award, granted by Radio Galicia Cadena Ser (2016)

“MAURICE MARIE JANOT AWARD” granted by the European Pharmaceutical Society (APGI). This is the most prestigious award in Pharmaceutical Technology in Europe.

“CRS FOUNDERS AWARD”, granted by the Controlled Release Society, Inc. (CRS, Inc)

“CRS OUTSTANDING SERVICE AWARD”, granted by the Controlled Release Society, Inc. (CRS, Inc)

“CRS WOMEN IN SCIENCES AWARD”, granted by the Controlled Release Society, Inc. (CRS, Inc)

“Burdinola Research Award”, granted by Burdinola company to the best scientists in Spain in Nanomedicine and Tissue Engineering (2021)

“Honorary Award for Excellence in Scientific Research”, AstraZeneca Foundation (2021)

“National Nanotechnology Award”, NOB166 company (2021)

XI. b. Awards granted by scientific editorials

Award of the “European Journal of Pharmaceutics and Biopharmaceutics” to the best scientific article published in 2001:
Gref R., Quellec P., Sánchez A., Calvo P., Dellacherie E., Alonso M.J., Development and characterization of CyA-loaded poly(lactic acid)-poly(ethylene glycol) micro and nanoparticles. Comparison with conventional PLA particulate carriers, European J.Pharm. Biopharm., 51, 111 (2001)

Special mention of the Editorial Committee of Elsevier Science for the most visited research article in 2002:
Vila A., Sánchez A., Tobío M., Calvo P., Alonso M.J., Design of Biodegradable particles for protein delivery, J. Control. Release, 78, 15 (2002)

Award of the “European Journal of Pharmaceutics and Biopharmaceutics” for the most citeted scientific article in the period 2004-2008:
Vila A., Sánchez A., Janes K. A., Behrens I., Kissel T., Vila Jato J. L. y Alonso M. J.
Low molecular weight chitosan nanoparticles as new carriers for nasal vaccine delivery in mice Eur. J. Pharm. Biopharm. 57, 123 (2004)

Award of the “European Journal of Controlled Release” for the most cited scientific article in 2005:
Prego C., García M., Torres D. y Alonso M.J., Transmucosal Macromolecular Drug Delivery, J. Control. Rel. 101, 151 (2005)

Distinction of the American Chemical Society (ACS) to the fourth most visited article of Biomacromolecules in 2005:
Csaba N., Caamaño P., Sánchez A., Domínguez F., Alonso M.J., PLGA :poloxamer and PLGA: poloxamine blend nanoparticles: new carriers for gene delivery, Biomacromolecules, 6, 271 (2005)

XI. c. Career awards granted by highly recognized institutions

Extraordinary Ph.D. award for the best Ph.D. of the Faculty of Pharmacy, USC, 1985

ELOY DÍEZ Award granted by the Eloy Díez Foundation to the best PhD of the year, 1982.

“Novoa Santos” Award (2011), granted by the Novoa Santos Foundation of Doctors in Medicine.

“King Jaume I” Award on New Technologies. This is the most prestigious award given in Spain to Spanish researchers, in recognition of an outstanding research career (2011).

Medal of the General Council of Pharmacy (2012), granted by the General Council of Pharmacy, Spain.

“Josefa Wonenburguer” Women in Sciences Award granted by the Xunta de Galicia (2013)

Galician Excellence in Science and Medicine, title granted by The Asociación de
Empresarios Gallegos de Cataluña (AEGA-CAT) (2017)

“Castelao Medal” Award, the most important recognition granted by the Xunta de Galicia (2018)

Award of Excellence in Research and Education granted by the Ministry of Sciences and Innovation (2020)

“Xi Lección Conmemorativa Maimónides” Award, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba (2021)

“Juan de la Cierva National Award in the area of Technology Transfer granted by the Ministry of Sciences and Innovation (2022)

“ASEICA Woman and Science 2022” and “ASEICA Social Commitment” Award, Spanish Association for Cancer Research (2022)

“Doctora Alcalá Award”, University of Alcalá de Henares (2022)

“Hamilton Medal”, Queens University of Belfast (2025)

– Participation as a president/ governor or scientific board member scientific societies

1995-97: Founder and president of the Board of Directors of the “Spanish Portuguese Chapter of the Controlled Release Society”, Spain

1995-98: “Governor of the Controlled Release Society Inc.”, USA

1998-00: Member of the “Board of Pharmaceutical Sciences” (1998-00), “(FIP) International Pharmaceutical Federation”, USA

1997-00: Member of the “Scientific Advidsory Board”, “(APGI) Association de Pharmacie Galénique Industrielle”, France

1997-00: Secretary of the Board of Directors of the “Spanish Portuguese Chapter of the Controlled Release Society”, Spain

2003-07: “Individual member representative”, (EUFEPS) European Federation for Pharmaceutical Sciences, Sweden

2012-2015: Member of the Advisory Board of the “Controlled Release Society (CRS, Inc).”

2013-16: Member of the Board –Director-at-Large- of the Controlled Release Society (CRS, Inc.)

2016-17: Secretary of the Controlled Release Society (CRS, Inc.)

2017-18: President-Elect of the Controlled Release Society (CRS, Inc.)

2018-2019: President of the Controlled Release Society (CRS, Inc.)

2019-2020: Past President of the Controlled Release Society (CRS, Inc.)

– Participation as editor or member of editorial boards of journals in the field of drug delivery

Editor-in-Chief of the Drug Delivery and Translational Research
Pharmaceutical Research
Journal of Controlled Release
International Journal of Pharmaceutics
European Journal of Pharmaceutics and Biopharmaceutics
European Journal of Pharmaceutical Sciences
Drug Development and Industrial Pharmacy
Drug Delivery Sciences & Technologies
J. Microencapsulation
Nanomedicine
Regenerative Engineering and Translational Medicine

– Participation in scientific/organizing committees of scientific international conferences

1st Spanish-Portuguese Conference on Controlled Drug Delivery, Santiago de Compostela, Spain, September, 1995

In vitro/In vivo Correlations Applicable to Extended-Release Formulations, Controlled Release Society Workshop, París, France, July, 2000

6th European Intensive Course on New Forms and New Routes of Administration for Drugs
Santiago de Compostela, Spain, February, 2000

32rd International Symposium on Controlled Release of Bioactive Materials, Viena, July, 2006

48th Journées Galéniques de St. Rémy de Provence, It’s Just Mucosa, Get Over It!, St. Rémy de Provence, September, 2014

7th International Meeting on Biotechnology, Biospain 2014, Fantastic Voyage: The upcoming Drugs, Santiago de Compostela, September, 2014

“Advanced Oncological Therapies”, Areces Foundation, Madrid, Spain, October, 2014.

19th International Symposium on Microencapsulation, Pamplona, Spain, 2014

21st International Symposium on Microencapsulation, Faro Portugal, 2017

Oral Peptide Delivery Workshop, Controlled Release Society, New York, July 2018

13rd Controlled Drug Delivery Conference- SPLC-CRS”, Santiago de Compostela, 2020

Organization of the Workshop on Alzheimer diseases and current technologies, IMDEA Institute, Madrid, March 2023