Neuropsychological characteristics in children of alcoholics: familial density.

The purpose of high-risk studies is to find characteristics that allow the identification of subjects with a higher vulnerability to alcoholism. The aim of this research was to verify if the familial density criterion is useful for subtyping children of alcoholics with different neuropsychological characteristics. Method: A battery of neuropsychological tests was administered to 102 boys and girls of 7-15 years of age; 66 were children of alcoholics with a high (n = 32) and low (n= 34) familial density of alcoholism, and 36 were children of nonalcoholic fathers with a negative family history of the disorder. The battery included tests to assess attention, visuospatial abilities and frontal functions. Results: MANCOVAs showed that high-density children scored lower than children of nonalcoholic fathers in attentional and visuospatial tasks. There were no differences between low-density and negative family history children in these cognitive domains. Conclusions: These results suggest that children of alcoholics are not a homogeneous group. Children with multigenerational alcoholism, but not children with an alcoholic father, showed reduced performance in specific cognitive areas.