A recent article by the research group led by M. Eugenio Vázquez and Miguel Vázquez López, in collaboration with other researchers of the Universidad Autónoma de Barcelona, CiQUS and Universitá di Pisa (Italy), has been selected as front cover of the issue 3 (21 January 2016) of the journal Dalton Transactions.
Understanding the way in which peptides and proteins fold into functional architectures in an autonomously-guided mechanism defined by the amino acid sequence, that is the protein folding problem, has been a formidable scientific challenge since its identification more than 50 years ago.
In this work (Dalton Trans., 2016, 45, 881-885) the authors describe the folding process of a family of mononuclear metallopeptides using high-level theoretical calculations and kinetic data.
They have described important factors that influence the folding of peptide ligands into chiral structures. Therefore, these studies could help improve the knowledge about the folding mechanism in metallopeptides and metalloproteins