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Publicacións

2025

Discovery of N-substituted-2-((arylethyl)amino)-2-(2-methoxyphenyl) acetamides: A novel family of antiplatelet agents
L. Rodríguez, C. Rodríguez, J. Azuaje, R. Prieto-Díaz, A.L. Martínez, M.I. Loza, J. Brea, D. Reza, E. Sotelo, E. Fuentes

2024

N-Adamantyl-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as Fluorescent Probes to Detect Microglia Activation through the Imaging of Cannabinoid Receptor Subtype 2 (CB2R)
F. Intranuovo, M. Majellaro, F. Mastropasqua, P. Delre, F.S. Abatematteo, G.F. Mangiatordi, A. Stefanachi, J. Brea, M.I. Loza, C. Riganti, A. Ligresti, P. Kumar, D. Esposito, L. Cristino, A. Nicois, L. González, M.G. Perrone, N.A. Colabufo, E. Sotelo, C. Abate, M. Contino

Exploring Biginelli-based scaffolds as A2B adenosine receptor antagonists: Unveiling novel structure-activity relationship trends, lead compounds, and potent colorectal anticancer agents
R. Prieto-Díaz, H. Fojo-Carballo, M. Majellaro, T. Tandarić, J. Azuaje, J. Brea, M.I. Loza, J. Barbazán, G. Salort, M. Chotalia, I. Rodríguez-Pampín, A. Mallo-Abreu, M.R. Paleo, X. García-Mera, F. Ciruela, H. Gutiérrez-de-Terán, E. Sotelo

Gemcitabine-Vitamin E Prodrug-Loaded Micelles for Pancreatic Cancer Therapy 
M. Perira-Silva, D. Miranda-Pastoriza, L. Diaz-Gomez, E. Sotelo, A.C. Paiva-Santos, F. Veiga, A. Concheiro, C. Alvarez-Lorenzo

2023

A Robust and Efficient FRET-Based Assay for Cannabinoid Receptor Ligands Discovery 
G. Navarro, E. Sotelo, I. Raïch, M.I. Loza, J. Brea, M. Majellaro

Pharmacological insights emerging from the characterization of a large collection of synthetic cannabinoid receptor agonists designer drugs
C. Gioé-Gallo, S. Ortigueira, J. Brea, I. Raïch, J. Azuaje, M.R. Paleo, M. Majellaro, M.I. Loza, C.O. Salas, X. García-Mera, G. Navarro, E. Sotelo

Fluorescence based HTS-compatible ligand binding assays for dopaine D3 receptors in baculovirus preparation and live cells
M.-J. Tahk, T. Laassfeld, E. Meriste, J. Brea, M.I. Loza, M. Majellaro, M. Contino, E. Sotelo, A. Rinken

Multicomponent Reaction-Assisted Drug Discovery: A Time- and Cost-Effective Green Approach Speeding Up Identification and Optimization of Anticancer Drugs 
G. Graziano, A. Stefanachi, M. Contino, R. Prieto-Díaz, A. Ligresti, P. Kumar, A. Scilimati, E. Sotelo, F. Leonetti

Development of Fluorescent 4-[4-(3H-Spiro[isobenzofuran-1,4′-piperidin]-1′-yl)butyl]indolyl Derivatives as High-Affinity Probes to Enable the Study of σ Receptors via Fluorescence-Based Techniques
F.S. Abatematteo, M. Majellaro, B. Montsch, R. Prieto-Díaz, M. Niso, M. Contino, A. Stefanachi, C. Riganti, G.F. Mangiatordi, P. Delre, P. Heffeter, E. Sotelo, C. Abate

N-adamantyl-anthranil amide derivatives: New selective ligands for the cannabinoid receptor subtype 2 (CB2R)
G. Graziano, P. Delre, F. Carofiglio, J. Brea, A. Ligresti, M. Kostrzewa, C. Riganti, C. Gioè-Gallo, M. Majellaro, O. Nicolotti, N.A. Colabufo, C. Abate, M.I. Loza, E. Sotelo, G.F. Mangiatordi, M. Contino, A. Stefanachi, F. Leonetti