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Publicacións

2023

Exploring the Effect of Halogenation in a Series of Potent and Selective A2B Adenosine Receptor Antagonists
R. Prieto-Díaz, M. González-Gómez, H. Fojo-Carballo, J. Azuaje, A. El Maatougui M. Majellaro, M.I. Loza, J. Brea, V. Fernández-Dueñas, M.R. Paleo, A. Díaz-Holguín, B. Garcia-Pinel, A. Mallo-Abreu, J.C. Estévez, A. Andújar-Arias, X. Garcia-Mera, I. Gomez-Tourino, F. Ciruela, C.O. Salas, H. Gutiérrez-de-Terán, E. Sotelo

Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase
F. Intranuovo, L. Brunetti, P. DelRe, G.F. Mangiatordi, A. Stefanachi, A. Laghezza, M. Niso, F. Leonetti, F. Loiodice, A. Ligresti, M. Kostrzewa, J. Brea, M.I. Loza, E. Sotelo, M. Saviano, N.A. Colabufo, C. Riganti, C. Abate, M. Contino

2022

Identification of A2BAR as a potential target in colorectal cancer using novel fluorescent GPCR ligands
J. Barbazán, M. Majellaro, A.L. Martínez, J.M. Brea, E. Sotelo, M. Abal

Flavanol Content and Nutritional Quality of Wastes from the Making of White and Rosé Wines from Mountain Vineyards
S. Boso, J.-L. Santiago, P. Gago, E. Sotelo, I. Álvarez-Acero, M.C. Martínez

A2B adenosine receptor antagonists rescue lymphocyte activity in adenosine-producing patient-derived cancer models
A.H.M. Tay, R. Prieto-Díaz, S. Neo, L. Tong, X. Chen, V. Carannante, B. Önfelt, J. Hartman, F. Haglund, M. Majellaro, J. Azuaje, X. Garcia-Mera, J.M. Brea, M.I. Loza, W. Jespers, H. Gutiérrez-de-Teran, E. Sotelo, A. Lundqvist

Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A1 Antagonists
C. Val, C. Rodríguez-García, R. Prieto-Díaz, A. Crespo, J. Azuaje, C. Carbajales, M. Majellaro, A. Díaz-Hoguín, J.M. Brea, M.I. Loza, C. Gioé-Gallo, M. Contino, A. Stefanachi, X. García-Mera, J.C. Estévez, H. Gutiérrez-de-Terán, E. Sotelo

Exploring Non-orthosteric Interactions with a Series of Potent and Selective A3 Antagonists
D. Miranda-Pastoriza, R. Bernárdez, J. Azuaje, R. Prieto-Díaz, M. Majellaro, A.V. Tamhankar, L. Koenekoop, A. González, C. Gioé-Gallo, A. Mallo-Abreu, J. Brea, M.I. Loza, A. García-Rey, X. García-Mera, H. Gutiérrez-de-Terán, E. Sotelo

Enantiomeric Separation and Molecular Modelling of Bioactive 4-Aryl-3,4-dihydropyrimidin-2(1H)-one Ester Derivatives on Teicoplanin-Based Chiral Stationary Phase
I. Bolognino, A. Carrieri, R. Purgatorio, M. Catto, R. Caliandro, B. Carrozzini, B.D. Belviso, M. Majellaro, E. Sotelo, S. Cellamare, C.D. Altomare

2021

Deciphering conformational selectivity in the A2A adenosine G protein-coupled receptor by free energy simulations
W. Jespers, L.H. Heitman, A.P. Ijzerman, E. Sotelo, G.J.P. van Westen, J. Åqvist, H. Gutiérrez-de-Terán

Similarities and differences upon binding of naturally occurring Δ9-tetrahydrocannabinol-derivatives to cannabinoid CB1 and CB2 receptors
I. Raïch, R. Rivas-Santistesban, A. Lillo, J. Lillo, I. Reyes-Resina, X. Nadal, C. Ferreiro-Vera, V.S. de Medina, M. Majellaro, E. Sotelo, G. Navarro, R. Franco