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Publicacións

2014

Structure-Based Design of New KSP-Eg5 Inhibitors Assisted by a Targeted Multicomponent Reaction
C. Carbajales, M.A. Prado, H. Gutiérrez de Terán, A. Cores, J. Azuaje, S. Novio, M.J. Núñez, B. Fernández García, E. Sotelo, X García Mera, P. Sánchez Lazo, M. Freire Garabal, A. Coelho

Ugi-Based Approaches to Quinoxaline Libraries
J. Azuaje, A. El Maatougui, X. García Mera, E. Sotelo

2013

Discovery of 3,4-Dihydropyrimidin-2(1H)-ones As a Novel Class of Potent and Selective A2B Adenosine Receptor Antagonists
A. Crespo, A. El Maatougui, P. Biagini, J. Azuaje, A. Coelho, J. Brea, M.I. Loza; M.I. Cadavid, X. GarcíaMera, H. Gutierrez de Terán, E. Sotelo

Selective and potent adenosine A3 receptor antagonists by methoxyaryl substitution on the N-(2,6-diarylpyrimidin-4-yl)acetamide scaffold
V. Yaziji, D. Rodríguez, A.Coelho, X. García-Mera, A. El Maatougui, J. Brea, M. I. Loza, M. I. Cadavid, H. Gutiérrez-de-Terán, E. Sotelo

Multicomponent Assembly of Diverse Pyrazin-2(1H)-one Chemotypes
J. Azuaje; A. El Maatougui; J.M. Pérez-Rubio; A. Coelho; F. Fernández; E. Sotelo

Copper-Catalyzed Huisgen 1,3-Dipolar Cycloaddition under Oxidative Conditions: Polymer-Assisted Assembly of 4-Acyl-1-Substituted-1,2,3-Triazoles
P.M. Diz, A. Coelho, A. El Maatougui, J. Azuaje, O. Caamaño, A. Gil, E. Sotelo

Three-Component Assembly of Structurally Diverse 2-Aminopyrimidine-5-carbonitriles
C. Val, V. Jaziji, A. Coelho, J. Auaje, A. Maatougui, C. CArbajales, E. Sotelo

2012

Discovery and Preliminary SAR of 5-Arylidene-2,2-Dimethyl-1,3-Dioxane-4,6-Diones as Platelet Aggregation Inhibitors
El Maatougui, A.; Azuaje, J.; Coelho, A.; Cano, E.; Yañez, M.; Yaziji, V.; Carbajales, C.; Sotelo. E.

2011

Silica-Supported Aluminum Chloride-Assisted Solution Phase Synthesis of Pyridazinone-Based Antiplatelet Agents
A.El Maatougui, J. Azuaje, E. Sotelo, O. Caamaño, A.Coelho

Convergent Assembly of Structurally Diverse Quinazolines
A. Crespo, A. Coelho, P. Diz, F. Fernández, H. Novoa de Armas, E. Sotelo