ECTS credits ECTS credits: 6
ECTS Hours Rules/Memories Hours of tutorials: 2 Expository Class: 38 Interactive Classroom: 20 Total: 60
Use languages Spanish, Galician
Type: Ordinary Degree Subject RD 1393/2007 - 822/2021
Departments: Forensic Science, Pathological Anatomy, Gynaecology and Obstetrics and Paediatrics
Areas: Toxicology
Center Faculty of Pharmacy
Call: First Semester
Teaching: With teaching
Enrolment: Enrollable
To understand the basic concepts of toxicology and the main factors influencing toxicity. To understand the basic principles of toxicokinetics and the main mechanisms of toxicity in chemical substances. To become familiar with the different techniques used in the toxicity assessment of a new chemical substance. To acquire basic knowledge of how to diagnose and treat acute poisoning. To understand the main analytical techniques useful in toxicology and their applications. To understand the main toxic risks of pharmaceuticals and drugs of abuse of greatest toxicological interest.
Block I. Basic Principles
Lesson 1. Toxicology. Concept of Toxicity
Lesson 2. Toxic action
Lesson 3. Mechanisms of toxicity
Lesson 4. Toxicological assessment procedures
Block II. Diagnosis and Treatment in Toxicology
Lesson 5. Intoxications. General diagnosis and treatment
Lesson 6. Introduction to toxicological analysis
Lesson 7. Sample treatment
Lesson 8. Analytical techniques applied to Toxicology
Block III. Systems Toxicology
Lesson 9. Toxic effects on the liver
Lesson 10. Toxic effects on the kidney
Lesson 11. Toxic effects on the nervous system
Lesson 12. Toxic effects on the cardiovascular system
Lesson 13. Toxic effects on the respiratory system
Lesson 14. Toxic effects on the blood
Section IV. Adverse reactions and intoxications by substances of health interest
Lesson 15. Drugs of abuse
Lesson 16. Analgesics and antipyretics
Lesson 17. Psychoactive pharmaceuticals
Lesson 18. Other pharmaceuticals and toxic substances of interest
Basic bibliography
Klaassen CD, Watkins II JB. Casarett & Doull's Essentials of Toxicology. 4ª Ed. New York: McGraw-Hill; 2021.
Repetto M, Repetto Kuhn, G. Toxicología Fundamental. 5ª Ed. Madrid: Díaz de Santos; 2024.
Villanueva Cañadas E, Gisbert Calabuig JA. Medicina Legal y Toxicología. 8ª Ed. Barcelona: Elsevier; 2024
Delgado Bueno S, Bandres Moya,F. Medina Crespo M,Torrecilla Jimenez JM. Tratado de Medicina Legal yCiencias Forenses. Tomo II: Toxicología forense.Daño corporal o psico-físico. Daño cerebraladquirido. Barcelona: Bosch; 2012
Complementary bibliography
Nogué Xarau S, Martínez Sánchez L, Salgado García, E. Toxicología Clínica. Bases para el diagnóstico y el tratamiento de las intoxicaciones en servicios de urgencias, áreas de vigilancia intensiva y unidades de toxicología. 2ªEd. Barcelona: Elsevier España, 2024.
Morán Chorro I, Baldirà Martínez de Irujo J, Marruecos-Sant L, Nogué Xarau S. Toxicología Clínica. Madrid: Grupo Difusión, 2011. https://www.fetoc.es/asistencia/Toxicologia_clinica_libro.pdf
Hayes AW, Kruger CL. Principles and Methods of Toxicology, 6ªed, Boca Raton: CRC Press, Taylor & Francis Group; 2014.
Levine B, Kerrigan S. Principles of Forensic Toxicology. Switzerland: Springer Nature; 2020.
Karch SB, Drummer O. Karch’s Pathology of Drug Abuse. 5ª Ed. London: CRC Press; 2021.
Dart R.C. Medical Toxicology. Philadelphia: Lippincott Williams & Wilkins; 2004.
Ellenhorn MJ, Barceloux DG. Medical Toxicology, 2ªed. Baltimore: Willians & Willians;1997.
Bello Gutierrez J. y López de Ceraín Salsamendi A. Fundamentos de Ciencia Toxicológica. Madrid: Diaz de Santos; 2001.
Niesink R.J.M., De Vries J. y Hollinger M.A. Toxicology: Principles and Applications. New York:CRC Press;1996.
Skills or abilities:
H/D 03. Evaluate the toxicological effects of substances and design and apply the corresponding tests and analyses.
H/D 05. Develop communication and information skills, both oral and written, to deal with patients and users of the center where they carry out their profesional activity.
H/D 06. Promote work and collaboration skills in multidisciplinary teams and those related to other healthcare professionals.
H/D 09. Estimate the risks associated with the use of chemical substances and laboratory processes.
H/D 12. Develop skills related to the beneficial effects of medicinal plants and understand the health risks associated with their misuse.
H/D 20. Evaluate the toxicological effects of substances and design and apply the corresponding tests and analyses.
Competencies:
Comp 01. Analytical and synthetic skills.
Comp 02. Ability to organize and plan.
Comp 03. Oral and written communication in one's own language.
Comp 04. Knowledge of a second language.
Comp 05. Basic computer skills.
Comp 06. Information management skills (ability to search and analyze information from various sources).
Comp 07. Problem-solving.
Comp 08. Decision-making.
Interpersonal skills:
Comp 10. Critical and self-critical thinking.
Comp 11. Teamwork.
Comp 12. Interpersonal skills.
Comp 17. Ethical commitment.
Comp 18. Ability to apply knowledge in practice.
Comp 20. Ability to learn.
Comp 21. Ability to adapt to new situations.
Comp 23. Leadership.
Comp 25. Ability to work independently.
Comp 28. Concern for quality.
A) Large group lectures:
Lessons taught by the professor can take various formats (theory, general guidelines for the subject, etc.). Over the course of a four-month period, 30 hours of lectures will be taught, covering the most important and complex aspects of the syllabus. Students will be left to complete individual work based on the fundaments presented by the professor.
B) Interactive small group lectures - SEMINAR:
Students actively participate in these classes in various ways: giving a short presentation, answering questions from the professor or other students, raising issues related to the topic, etc. The professor and students may be supported by audiovisual and computer aids if necessary. Evaluation tests may be performed in some or all sessions. Attendance at these classes is mandatory for continuous assessment.
C) Practical classes:
Attendance at these classes is mandatory, so students will not be evaluated if they do not complete the practical classes. They will be organized as follows:
• Laboratory: These classes are carried out in the practical laboratory of the Faculty of Pharmacy. Students acquire laboratory skills and consolidate the knowledge acquired in the theoretical classes. After the professor’s explanation, students will, individually or in small groups, carry out the experiments and calculations necessary to achieve the objectives of the practical class, recording the practical performance, calculations and results in their own report, that will be given to the professor and evaluated as part of the continuous assessment grade.
• Interactive computer practice: Searching for bibliographic information in databases and on topics related to Toxicology.
D) Other: Debate, case studies, problem-solving, collaborative learning techniques, etc.
The evaluation for the two opportunities available during the academic year will be conducted in the same manner and will consist of two parts: a theoretical exam and continuous assessment.
• Theoretical exam: accounts for 80% of the final grade (maximum 8 points).
This will be a written test exam and/or short-question exam that will be held on the dates scheduled in the Faculty of Pharmacy's official exam calendar for the two opportunities. The student must obtain at least 45% of the maximum grade (minimum grade 3.6 out of 8) as a requirement to add the continuous assessment grade.
• Continuous assessment: accounts for 20% of the final grade (maximum 2 points).
It will be calculated based on attendance at lectures, participation in practical classes and the report submitted at the end, and the grades obtained in the interactive classes. Attendance at mandatory activities will be monitored by taking attendance and recording the results in an Excel spreadsheet. For attendance control for other activities, each professor will establish the monitoring system to be used. Lack of attendance that does not exceed 10% of the scheduled hours does not require justification, except in the case of mandatory activities. The continuous assessment grade will be distributed among the different activities:
Attendance to lectures: 12.5% (maximum 0.25 points).
Practical classes: 12.5% (maximum 0.25 points).
Interactive classes: 75% (maximum 1.5 points).
The acquired skills will be evaluated as follows:
Theoretical exam: Comp 01, Comp 03, Comp 07, Comp 08, Comp 18, Comp 20, Comp 28
Interactive classes: Comp 01, Comp 02, Comp 03, Comp 04, Comp 05, Comp 06, Comp 07, Comp 08, Comp 10, Comp 11, Comp 12
Comp 17, Comp 18, Comp 20, Comp 21, Comp 23, Comp 25, Comp 28
Laboratory practices: Comp 01, Comp 02, Comp 04 Comp 06. Comp 07. Comp 08. Comp 10. Comp 11. Comp 12. Comp 17. Comp 18. Comp 20. Comp 21. Comp 23. Comp 25. Comp 28.
Considerations to keep in mind:
o Attendance at the practical classes is required to take the final exam and pass the course.
o To pass the course, a minimum final grade of 5 out of 10 is required (theoretical exam + continuous assessment).
o In the theoretical exam, a student must obtain at least 45% of the maximum grade (minimum grade 3.6 out of 8) as a requirement to add the continuous assessment grade.
o To obtain a score in each of the seminars, it is mandatory to attend them and actively participate in the proposed activities.
o The continuous assessment grade will be retained for 3 consecutive academic years.
o On the second opportunity, only the final exam will be held, and the continuous assessment grade will be maintained. The maximum grade on which the exam will be graded and the minimum required will be those described for the first opportunity.
*Evaluation criteria for students exempt from class attendance:
For students who have been granted exemption from class attendance, completing the practical classes will be mandatory, and the grade will be the one obtained on the final exam.
Theoretical teaching .......................................... 30
Interactive seminar teaching ..................................... 14
Interactive laboratory/computer classroom teaching .....10
Student tutoring ..................................... 2
Exams and revision .......................................... 4
Student personal work ............................ 90
General recommendations:
• Active participation in class and raising questions during lectures and interactive sessions.
• Use of the recommended bibliography.
• Use of materials and documents provided by the professors.
Recommendations for assessment:
It is important that students spend at least 30 minutes studying the subject after each class, completing their notes with the help of the recommended bibliography. Although this subject is easy to understand, it requires continued effort and dedication.
Students should ask any questions that arise, both in class and during tutorials.
When taking the exam, it is essential to read each question carefully to avoid incorrect answers, as far as possible.
Recommendations for the second opportunity exam:
Students should review their exams to identify their mistakes and to determine in which sections of the subject they need to make a greater effort in order to pass the exam.
It is also important to attend tutorials to resolve any questions they may have for a better understanding of the subject.
Inés Sánchez Sellero
- Department
- Forensic Science, Pathological Anatomy, Gynaecology and Obstetrics and Paediatrics
- Area
- Toxicology
- ines.sanchez.sellero [at] usc.es
- Category
- Professor: University Lecturer
Ana Maria Bermejo Barrera
- Department
- Forensic Science, Pathological Anatomy, Gynaecology and Obstetrics and Paediatrics
- Area
- Toxicology
- Phone
- 881812206
- anamaria.bermejo [at] usc.es
- Category
- Professor: University Professor
Angelines Cruz Landeira
- Department
- Forensic Science, Pathological Anatomy, Gynaecology and Obstetrics and Paediatrics
- Area
- Toxicology
- Phone
- 881812317
- angelines.cruz [at] usc.es
- Category
- Professor: University Professor
Ana De Castro Rios
Coordinador/a- Department
- Forensic Science, Pathological Anatomy, Gynaecology and Obstetrics and Paediatrics
- Area
- Toxicology
- ana.decastro [at] usc.es
- Category
- Professor: University Lecturer
Miriam Blanco Ces
- Department
- Forensic Science, Pathological Anatomy, Gynaecology and Obstetrics and Paediatrics
- Area
- Toxicology
- miriamblanco.ces [at] usc.es
- Category
- USC Pre-doctoral Contract
| Monday | |||
|---|---|---|---|
| 11:00-12:00 | Grupo A/CLE_01 | Spanish | 5035 Classroom 6 Faculty of Law |
| 18:00-19:00 | Grupo B/CLE_02 | Spanish, Galician | 5035 Classroom 6 Faculty of Law |
| Tuesday | |||
| 11:00-12:00 | Grupo A/CLE_01 | Spanish | 5035 Classroom 6 Faculty of Law |
| 18:00-19:00 | Grupo B/CLE_02 | Galician, Spanish | 5035 Classroom 6 Faculty of Law |
| Wednesday | |||
| 11:00-12:00 | Grupo A/CLE_01 | Spanish | 5035 Classroom 6 Faculty of Law |
| 18:00-19:00 | Grupo B/CLE_02 | Galician, Spanish | 5035 Classroom 6 Faculty of Law |
| Thursday | |||
| 11:00-12:00 | Grupo A/CLE_01 | Spanish | 5035 Classroom 6 Faculty of Law |
| 18:00-19:00 | Grupo B/CLE_02 | Spanish, Galician | 5035 Classroom 6 Faculty of Law |
| Friday | |||
| 11:00-12:00 | Grupo A/CLE_01 | Spanish | 5035 Classroom 6 Faculty of Law |
| 18:00-19:00 | Grupo B/CLE_02 | Galician, Spanish | 5035 Classroom 6 Faculty of Law |