ECTS credits ECTS credits: 6
ECTS Hours Rules/Memories Student's work ECTS: 99 Hours of tutorials: 3 Expository Class: 24 Interactive Classroom: 24 Total: 150
Use languages Spanish, Galician
Type: Ordinary Degree Subject RD 1393/2007 - 822/2021
Departments: Biochemistry and Molecular Biology
Areas: Biochemistry and Molecular Biology
Center Faculty of Pharmacy
Call: First Semester
Teaching: Sin docencia (Extinguida)
Enrolment: No Matriculable
1. To know the chemical composition of the living matter, as well as the structure and properties of the biomoléculas.
2. To understand the enzymes function as catalysts in biological systems by the study of the basic enzimology and kinetical enzymatic. These theoretical knowledges applied to the biochemical analyses in the laboratory and to the resolution of practical problems.
3. Study the nucleic acids like biomoléculas transmissive of the genetic information, this study will cover from structural appearances until the main routes of the genetic information.
4. Introduction to the metabolism and study of the metabolic routes head offices of the intermediate metabolism
Programme of lectures:
The lectures will take place in 30 sessions of one hour each.
Item 1. The molecular logic of life. Production and consumption of energy. Chemical characteristics of living matter. Bioelements and biomolecules.
Item 2. Structure and function of amino acids, peptides and proteins.
Item 3. Enzymes. Enzyme kinetics. Mechanisms of enzymatic regulation.
Item 4. Structure and Function of carbohydrates: monosaccharides, oligosaccharides and polysaccharides. Glycoconjugates.
Item 5. Structure and function of lipids. Reserve lipids. Structural lipids. Lipids with specific biological activities. Lipoproteins
Item 6. Biological membranes and cellular transport.
Item 7. Structure and function of nucleotides and nucleic acids. Genes and chromosomes
Item 8. Pathways of genetic information replication, transcription and translation.
Item 9. Bioenergetics and metabolism. Overview of metabolism.
Item 10. Central routes of intermediary metabolism.
Interactive class schedule:
The lectures are supplemented with 8 hours of interactive classes, grouped into four sessions of 2 hours each. They students will discuss and resolve issues and problems related to the subject to be worked on previously. This material, in some cases, will be available on the website of the course and others will be provided by the teacher in class for interactive.
Program of practical lessons:
Laboratory practical classes were conducted in 5 sessions of 3 hours and one hour test at the end of the same
Practice 1. Obtaining a protein extract and partial purification of proteins.
Practice 2. Determination of protein concentration. Lowry method.
Practice 3. Separation and identification of human serum proteins.
Practice 4. Effect of substrate concentration on enzyme activity. Calculation of Km
Practice 5. Study of the variation of enzyme activity with pH.
Practice 6. Starch extraction and characteristic reactions of carbohydrates.
Practice 7. Extraction and reactions characteristic of lipids.
Basic Bibliography:
- Bioquímica. Conceptos esenciales. Feduchi y col. Editorial McGraw-Hill, 3ª ed.,2020.
- Lehninger. Principios de Bioquímica. Nelson y Cox. Editorial Omega. 6ª ed., 2015.
- Bioquímica. Curso básico. Stryer, Berg y Tymoczko. Editorial Reverté, S.A., 7ª ed. 2015
Complementary Bibliography:
- Bioquímica. Stryer, Berg y Tymoczko. Editorial Reverté, S.A., 7ª ed., 2013
- Bioquímica. Fundamentos para Medicina y Ciencias de la Vida. Werne rMüller-Esterl. Editorial Reverté. 2008.
- Fundamentos de Bioquímica. Voet, Voet, Pratt. Editorial Médica Panamericana. 4ª ed., 2016.
- Bioquímica y Biología Molecular para ciencias de la salud. Lozano y col. Editorial McGraw-Hill-Interamericana. 3ª ed., 2005.
- Bioquímica. Libro de texto con aplicaciones clínicas. Devlin. Editorial Reverté, S.A., 4ª ed., 2004.
Electronic bibliography:
- Bioquímica: fundamentos para Medicina y Ciencias de la vida. Muller-Esterl, Werner ; Brandt, Ulrich. Editorial Reverté. 2020.
- Bioquímica: libro de texto con aplicaciones clínicas. Devlin, Thomas M ; Canals, Francesc. Editorial Reverté. 2021.
- Bioquímica humana: curso básico. Macarulla, Jose M ; Goñi, Félix M. Ed. Reverté. 2021.
- Bioquímica Con aplicaciones clínicas. Stryer, Lubert L., Jeremy M. Berg, and John L. Tymoczko 7th ed. Barcelona: Editorial Reverté, 2018.
- Bioquímica. Conceptos esenciales. Feduchi y col. Editorial Panamericana, 3ª ed., 2021.
- Bioquímica: curso básico. Stryer, Berg y Tymoczko. Editorial Reverté, S.A., 7ª ed. 2014.
General skills:
3. Learn to apply the scientific method and acquire skills in managing information sources, literature, development of protocols.
10. Design, implement and evaluate reagents, clinical analytical methods and techniques, knowing the basics of medical tests and the nature and contents of the reports of laboratory diagnosis.
13. Develop communication and information skills, oral and written, to deal with patients and users of the facility where play their work.
14. Promote job skills and team collaboration.
Specific skills:
B01 Know the structures of biomolecules and their transformations in the cell
B07 Know the properties of cell membranes and drug delivery
B09 Know the main metabolic pathways involved in drug degradation
Transversal skills:
BI03 Basic general knowledge.
CS01 Ability to apply knowledge in practice.
CS03 Ability to learn
A) Large Group Lectures: Lesson taught by the teacher in setting out the theoretical approach to the subject. The USC virtual platform will support and complement the theoretical teaching.
B) Small group interactive classes: Theory and practice class in which we propose and solve applications of theory (problems, exercises..). The student participates actively in these in these clases by delivering exercises to the teacher, solving exercises in the classroom, etc. It includes written tests on specific sections. Attendance at these interactive classes is mandatory for continuous assessment.
C) Laboratory Practical classes: Students learn the skills specific to a laboratory and consolidates the knowledge gained in the lectures. For these practices, the student will have a laboratory manual. The student will perform these practical sessions in small groups, gathering in the manual the results, presenting them to the teacher at the end of each session. Attendance at these classes is mandatory.
D) Very small groups scheduled tutorials: Tutorials are scheduled by the Faculty. Further work is proposed to monitor the level of learning and understanding of the subject, clarification of doubts about the theory or practice, problems, exercises, readings or other tasks proposed.
E) The USC virtual platform to support and complement the theoretical and practical teaching as an important element of communication with the student. It is made available to students the resources and skills needed for the study of the subject.
1. The two calls for evaluation in the academic year will consist of three parts: theoretical exam, laboratory practical part and interactive part.
2. The theoretical exam will account for 70% of the final grade (maximum 7 points). The exam will be mixed, with multiple choice questions covering all the fundamental parts of the subject, and short and concrete questions, for evaluating the development of reasoning and the assimilation of the subject. It is necessary that the mark obtained in this test exceed 45% (3.2) the maximum (7) to assess the remaining sections.
3. The evaluation of the laboratory practical part will mean 10% (up 1 point) of the final grade. This assessment will include the work done by the student in the laboratory as well as the understanding of experimental results, to be conducted through a written test consisting of short questions.
Assistance to all the practical sessions and the final written test is mandatory to pass the subject of Biochemistry I.
Mark for the practical laboratory part will be maintained only during the two following academic years in the case of failing the course.
4. Evaluation of interactive classes will mean a 20% (up to 2 points) of the final grade. This assessment will be established taking into account: active participation in these classes, making of the proposed activities, marks to written tests about specific points proposed to the student, etc. Mark corresponding to this part will be maintained only for the ongoing academic course.
5. For the 2º call, only the theory exam needs to be done. Maximum mark for the qualification of this exam as well as the minimum requiered to pass are the same as for the 1st call.
6. The student must obtain five points over a total of ten to pass the subject.
7. The evaluation of the competences acquired in the subject will be done through the following ways:
Theoretical exam: B01, B07, B09, CI03, CS03
Laboratory classes: 3, 10, 13, 14, CI03, CS01, CS03
Interactive classes: 3, 10, 13, 14, B01, B07, B09, CI03, CS01, CS03
PRESENCE IN THE CLASS WORK HOURS
Large-group lectures 30
Small group interactive classes 8
Very small group tutorials 2
16 Labs
Testing and revision 4
Total hours of classroom work
in the classroom or laboratory 60
STUDENT PERSONNEL WORK HOURS
Individual self-study or group 60
Solving exercises, or other work 16
Orientation and resolution of questions 4
Preparation of laboratory work
and its reporting practices 6
Implementation and Review Exam 4
Total hours of personal work 90
It is advisable to attend the lectures and as far as possible to keep the study of matter per day.
- It is essential that students attempt to resolve the issues proposed in the lectures so they can raise their concerns to the teacher in the interactive classes.
- The use of the USC virtual is recomended since students can consult with the teacher questions via email. On this page will also be included material such as outlines, summaries, problems,.. to help students to pass the final exam.
- It is essential preparation practices before entering the laboratory. First, you should review the important theoretical concepts in each experiment and then you should read carefully the script of the practice, trying to understand the objectives and the development of the proposed experiment. Any doubts that might arise before or during practice must be discussed with the teacher
Maria Luz Perez-Paralle Mera
Coordinador/a- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- Phone
- 881816049
- luz.perez-paralle [at] usc.es
- Category
- Professor: University Lecturer
Marcelina Abad Caeiro
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- Phone
- 881814931
- marcelina.abad [at] usc.es
- Category
- Professor: University Lecturer
María Paz García Martínez
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- Phone
- 881814908
- paz.garcia [at] usc.es
- Category
- Professor: University Lecturer
Lisa Kay Busch
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- lisa.busch [at] usc.es
- Category
- Professor: Temporary PhD professor
Diana Llamazares Oliveras
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- diana.llamazares.oliveras [at] usc.es
- Category
- USC Pre-doctoral Contract
| Monday | |||
|---|---|---|---|
| 09:00-10:00 | Grupo C /CLE_03 | Spanish | 5035 Classroom 9. Faculty of Law |
| 15:00-16:00 | Grupo A /CLE_01 | Spanish | 5035 Classroom 11. Faculty of Law |
| 17:00-18:00 | Grupo B /CLE_02 | Spanish | 5035 Classroom 9. Faculty of Law |
| Tuesday | |||
| 09:00-10:00 | Grupo C /CLE_03 | Spanish | 5035 Classroom 9. Faculty of Law |
| 15:00-16:00 | Grupo A /CLE_01 | Spanish | 5035 Classroom 11. Faculty of Law |
| 17:00-18:00 | Grupo B /CLE_02 | Spanish | 5035 Classroom 9. Faculty of Law |
| Wednesday | |||
| 09:00-10:00 | Grupo C /CLE_03 | Spanish | 5035 Classroom 9. Faculty of Law |
| 15:00-16:00 | Grupo A /CLE_01 | Spanish | 5035 Classroom 11. Faculty of Law |
| 17:00-18:00 | Grupo B /CLE_02 | Spanish | 5035 Classroom 9. Faculty of Law |
| Thursday | |||
| 09:00-10:00 | Grupo C /CLE_03 | Spanish | 5035 Classroom 9. Faculty of Law |
| 15:00-16:00 | Grupo A /CLE_01 | Spanish | 5035 Classroom 11. Faculty of Law |
| Friday | |||
| 09:00-10:00 | Grupo C /CLE_03 | Spanish | 5035 Classroom 9. Faculty of Law |
| 15:00-16:00 | Grupo A /CLE_01 | Spanish | 5035 Classroom 11. Faculty of Law |