ECTS credits ECTS credits: 3
ECTS Hours Rules/Memories Student's work ECTS: 51 Hours of tutorials: 3 Expository Class: 9 Interactive Classroom: 12 Total: 75
Use languages Spanish, Galician
Type: Ordinary subject Master’s Degree RD 1393/2007 - 822/2021
Departments: Organic Chemistry
Areas: Organic Chemistry
Center Faculty of Chemistry
Call: Annual
Teaching: With teaching
Enrolment: Enrollable | 1st year (Yes)
Knowing the fundamental role that primary metabolites (carbohydrates, proteins , peptides and nucleic acids ) play in living organisms .
Gain knowledge of instrumental techniques for the isolation and structural determination of these natural substances.
Knowing the value of its synthesis in the development of biologically active compounds.
Topic 1. Introduction and historical aspects .
Topic 2. Peptides and proteins : structural aspects. Synthesis and modification. Design of functional proteins . Metalloproteins : types, methods of study, examples and applications
Topic 3. Nucleic acids: Structure, DNA synthesis. Sequencing, PCR, DNA recognition. DNA beyond biology: processing and storage; Nanomaterials.
Topic 4. Carbohydrates: structural aspects. Synthesis and modification. Glycoconjugates and their role in cellular communication. Glycocode. Glycotherapy.
1.- Molecular Biology of the Cell, B. Alberts et all, Garland Science, 2002
2.- Introduction to Bioorganic Chemistry and Chemical Biology. Vranken, D-V; Weiss, G.A. Garland Science 2012
3.- Nucleic Acids in Chemistry and Biology. Blackburn, M.: Gait, M.J.; Loakes, D.; Williams, D.M. (Editors). Rayal Society of Chemistry, 2006
4.- Peptides: Synthesis, Structures and Application. Gutte, B. Academic Press,.1995
5.- Introduction to Protein Structure. Brändén, C-I; Tooze, J. Garland Science 1999.
6.- Glycochemistry, Principles, Synthesis and Applications. Ed. Peng G. Wang, C. R. Betozzi. Marcel Dekker, New York, 2001.
7.- Concepts and Models in Bioinorganic Chemistry. Karls, R
8.- Metal Complex-DNA Interactions. Hadjiliadis, N.; Sletten, E. (Editors), Wiley, 2009.
9.- The Molecular and Supramolecular Chemistry of Carbohydrates. A chemical introduction to glicoscience. D. Serge. Oxford Science publications, 1997
10.- Introduction to Glycobiology. Taylor, M.E.; Drickamer, K. Oxford University press. 2011
11.- Carbohydrate Chemistry. Davies, B.G.; Fairbanks. A.J. Oxford Science publications, 2004
12.- Glycoscience, Synthesis of Substrate Analogs and Mimetics. Driguez, H; Thiem, J. Springer-Verlag, New York, 1997.
13.- Bioinorganic chemistry, inorganic elements in the chemistry of life: an introduction and guide. Kaim, W. Schwederski, B.,Klein, A. 2º ed. John Wiley, Chichester , 2013
14. Biological Inorganic Chemistry. An Introduction. Crichton, R.R. Elsevier, Amsterdam, 2008
BASIC AND GENERAL:
Have access (databases, scientific articles, etc.) to the necessary information and have enough criterion for their interpretation. Being Well adapted to follow future doctoral studies in multidisciplinary areas. Be able to publicly the results of a research making technical report. Have the ability to apply the scientific method and the principles of organic chemistry to formulate and solve complex problems.
SPECIFIC:
Know the most important synthetic methods in Biological Organic Chemistry, including the fundamentals of stereoselective processes, and be able to design synthetic routes to complex organic molecules. Know and understand the reaction mechanisms commonly accepted in Biological Organic Chemistry and The methods available for determination. Knowing the biological and medical applications of organic compounds.
CROSSED:
Handling tools of information and communications technology as well as access to online databases. Developing the capacity of scientific and technical communication in Spanish and English, both orally and writing, using the most common media. Apply the concepts, principles, theories or models related to organic chemistry to new or unfamiliar environments within multidisciplinary contexts. Demonstrate autonomous learning ability and work for the development of their professional life.
Scenario 1: adapted normality
Lectures, interactive classes in small group (seminars and exercises), interactive classes in very small group (tutorials).
A) Lectures: Lessons read by the professor who may have different formats (theory, exercises and/or general examples, the general guidelines of matter, etc.).
B) Interactive small group classes: theoretical/practical class that are proposed to solve applications of theory, exercises, etc. The student participates actively in these ways: delivery professor exercises, exercises in the classroom, etc.
C) Very small group classes (tutorials): theoretical/practical classes in activities such as monitoring of works directed, clarification of doubts about the theory, exercises, readings or other tasks proposed; and the presentation, discussion or comments of individual works or performed in small groups.
For the case of scenarios 2 or 3, see the observations section.
Scenario 1: adapted normality
The assesment of this subject will be done through continuous assessment and completion of a final examination. Access to examination should be conditioned to the participation in at least 80% of the lectures, seminars and tutorials). Continuous assessment (N1) will have a weight of 40% in the grade of the subject and consist of two components: interactive small group classes (seminars) and interactive classes in very small groups (tutorials). Seminars and tutorials include problem solving and practical cases (35%) and oral questions and issues during the course (5%). The final examination (N2) will cover the entire contents of the subject. And it will have a value of 60% The student's score will be obtained as result of applying the following formula:
Qualificaction = 0.4 x 0.6 x N1 + N2
N1 corresponding to the continuous assessment (scale 0-10) and the number N2 final exam (0-10 scale) numerical grade.
To pass the course, it will be an essential requirement be qualified as suitable in the lab and to get a minimum of 4.0 in the final exam.
For the case of scenarios 2 or 3, see the observations section.
The number of ECTS credits of the matter is 3 which correspond to 75 total hours of student work , distributed according to the following timetable:
CLASSWORK (HOURS)
Lectures in large group: 14
Small group interactive classes (seminars): 7
Very small group classes (tutorials): 3
Total working hours in the classroom: 24
HOMEWORK (HOURS)
Individual or group self- study: 15
Solving exercises, or other work proposed: 31
Preparation of exercises: 5
Total personal work hours: 51
It is very important to attend lectures .
It is essential to conduct a continuous study of matter .
Once class is useful to summarize the most relevant points
Solving exercises is key to learning this stuff.
It may be helpful to start with the issues resolved in manuals and reference support to continue after the exercises proposed at the end of each chapter.
Scenario 2: Distance
Teaching methodology:
The teaching of the exhibition can be carried out in its totality by telematic means (using the Moodle and MS Teams platforms), or combined with the face-to-face mode, in those teaching spaces where distance is possible. In the interactive teaching of seminars, physical and telematic attendance may be combined, up to a maximum of 50% of the hours of the subject in telematic mode, when distance requires it.
Tutorials will be preferably telematic.
Evaluation system:
The evaluation of this subject will be done through continuous assessment and a final exam.
The deliveries for continuous evaluation may be in person or virtually.
The final tests will preferably be telematic in nature.
The continuous evaluation will have a weight of 45% in the qualification of the subject.
The final exam will deal with all the contents of the subject and will have a weight of 55%.
The student's grade will not be lower than that of the final exam or that obtained by weighting with the continuous assessment.
In any case, to pass the course it will be a requirement to have the qualification of 4 over 10 in the final exam.
Scenario 3: Closing down the facility
Teaching methodology
All teaching (lectures, seminars and tutorials) will be completely virtual, using the Moodle and MS Teams platforms.
Evaluation system
The evaluation of this subject will be done through continuous assessment and a final examination.
The submissions for continuous evaluation will be exclusively virtual.
The final tests will be exclusively of a telematic nature (written or oral).
The continuous evaluation will have a weight of 45% in the qualification of the subject.
The final exam will deal with all the contents of the subject and will have a weight of 55%.
The student's grade will not be lower than that of the final exam or that obtained by weighting with the continuous assessment.
In any case, to pass the course it will be a requirement to have the qualification of 4 over 10 in the final exam.
In the case of fraudulent exercises or tests, the provisions of the "Regulations for the assessment of students' academic performance and the revision of qualifications" of the USC should be apply. (https://www.usc.es/export9/sites/webinstitucional/gl/normativa/descarga…)
Juan Carlos Estevez Cabanas
Coordinador/a- Department
- Organic Chemistry
- Area
- Organic Chemistry
- Phone
- 881815730
- juancarlos.estevez [at] usc.es
- Category
- Professor: University Professor
Jose Luis Mascareñas Cid
- Department
- Organic Chemistry
- Area
- Organic Chemistry
- Phone
- 881815737
- joseluis.mascarenas [at] usc.es
- Category
- Professor: University Professor
Marco Eugenio Vazquez Sentis
- Department
- Organic Chemistry
- Area
- Organic Chemistry
- Phone
- 881815738
- eugenio.vazquez [at] usc.es
- Category
- Professor: University Lecturer
| Wednesday | |||
|---|---|---|---|
| 11:00-13:00 | Grupo /CLE_01 | Spanish | Classroom 2.12 |