Publicaciones

  1. K+-Mediated vs Pd-Catalyzed Cyclotrimerization of 9,10-Didehydrotribenzo[8]annulene (TribenzoCOTyne): Stereodivergent Access to (α,α,α)- and (α,α,β)-Fragments of CubicGraphite

    Angew. Chem. Int. Ed. 2024, e202414017

    Jesús Bello-García, Jesús A. Varela, Carlos Saá

  2. One-Pot Rh(III)-Catalyzed Twofold C−H Activation/Oxidative Annulation of N-Arylpyrroles with Alkynes to Fluorescent Ullazines

    Adv. Synth. Catal. 2024, 366, 2312-2323

    Sergio Otero-Riesgo, Jesús A. Varela, Carlos Saá

  1. Palladium-Catalyzed [5+2] Rollover Annulation of 1-Benzylpyrazoles with Alkynes: A Direct Entry to Tricyclic 2-Benzazapines

    Org. Lett. 2023, 25, 5, 794–799

    Alejandro Suárez-Lustres, Nuria Martínez-Yáñez, Álvaro Velasco-Rubio, Jesús A. Varela, Carlos Saá

  2. Chemoselective Ru-Catalyzed Oxidative Lactamization vs Hydroamination of Alkynylamines: Insights from Experimental and Density Functional Theory Studies

    J. Org. Chem. 2023, 88, 1185-1193

    Andrés M. Álvarez-Constantino, Andrea Álvarez-Pérez, Jesús A. Varela, Giuseppe Sciortino, Gregori Ujaque, Carlos Saá

  1. Catalytic Lewis Base Additive Enables Selective Copper-Catalyzed Borylative a-C-H Allylation of Alicyclic Amines

    J. Am. Chem. Soc. 2022, 144, 16206-16216

    Borja Pérez-Saavedra, Álvaro Velasco-Rubio, Eva Rivera-Chao, Jesús A. Varela, Carlos Saá, Martín Fañanás-Mastral

  1. Pd-Catalyzed Allylic C-H Activation to Seven-Membered N,O-Heterocycles

    Chem. Commun. 2021, 57, 10915-10918

    Álvaro Velasco-Rubio, Jesús A. Varela, Carlos Saá

  2. Enantioenriched α-Vinyl 1,4-Benzodiazepines and 1,4-Benzoxazepines via Enantioselective Rhodium-Catalyzed Hydrofunctionalizations of Alkynes and Allenes

    J. Org. Chem. 2021, 86, 10889-10902

    Álvaro Velasco-Rubio, Rodrigo Bernárdez, Jesús A. Varela, Carlos Saá

  3. Nonplanar Tub-Shaped Benzocyclooctatetraenes via Halogen-Radical Ring Opening of Dihydrobiphenylenes

    Org. Lett. 2021, 23, 5539-5544

    Jesús Bello-García, Damián Padín, Jesús A. Varela, Carlos Saá

  1. Recent Advances in Transition‐Metal‐Catalyzed Oxidative Annulations to Benzazepines and Benzodiazepines

    Adv. Synth. Catal. 2020, 362, 4861-4875

    Álvaro Velasco-Rubio, Jesús A. Varela, Carlos Saá

  2. Oxidation of Alkynes via Catalytic Metal-Vinylidenes

    Synthesis 2020, 52, 2639-2649

    Andrea Álvarez-Pérez, Carlos Saá, Jesús A. Varela

  3. Cp*RuCl-Vinyl Carbenes: Two Faces and the Bifunctional Role in Catalytic Processes

    Chem. Eur. J. 2020, 26, 7470-7478

    Damián Padín, Jesús A. Varela, Carlos Saá

  4. Recent Advances in Ruthenium-Catalyzed Carbene/Alkyne Metathesis (CAM) Transformations

    Synlett 2020, 31, 1147-1157

    Damián Padín, Jesús A. Varela, Carlos Saá

  5. Palladium-Catalyzed [5 + 2] Heteroannulation of Phenethylamides with 1,3-Dienes to Dopaminergic 3‑Benzazepines

    Org. Lett. 2020, 22, 3591−3595

    Álvaro Velasco-Rubio, Jesús A. Varela, Carlos Saá

  6. Ruthenium-Catalyzed Tandem Carbene/Alkyne Metathesis/N−H Insertion: Synthesis of Benzofused Six-Membered Azaheterocycles

    Org. Lett. 2020, 22, 2621−2625

    Damián Padín, Jesús A. Varela, Carlos Saá

  1. Ruthenium-Catalyzed Oxidative Amidation of Alkynes to Amides

    Org. Lett. 2019, 21, 5346-5350

    Andrea Álvarez-Pérez, Miguel A. Esteruelas, Susana Izquierdo, Jesús A. Varela, Carlos Saá

  2. Rh(III)-Catalyzed [5 + 2] Oxidative Annulation of Cyclic Arylguanidines and Alkynes to 1,3-Benzodiazepines. A Striking Mechanistic Proposal from DFT

    Org. Lett. 2019, 21, 1779-1783

    Nuria Martínez-Yáñez, Jaime Suárez, Ana Cajaraville, Jesús A. Varela, Carlos Saá

  1. Copper(I)-Catalyzed Tandem Carboarylation/Cyclization of Alkynyl Phosphonates with Diaryliodonium Salts

    ACS Catalysis 2017, 7, 6104–6109

    Borja Pérez-Saavedra, Nuria Vázquez-Galiñanes, Carlos Saá , Martín Fañanás-Mastral

  2. Vinyl Ruthenium Carbenes: Valuable Intermediates in Catalysis

    New Horizons of Process Chemistry (Eds.: K. Tomioka, T. Shioiri, H. Sajiki, ISBN: 978-981-10-3420-6), Springer Nature Singapore Pte Ltd. 2017, pp: 89-102

    Damián Padín, Jesús A. Varela, Carlos Saá

  3. N‑Doped Cationic PAHs by Rh(III)-Catalyzed Double C−H Activation and Annulation of 2‑Arylbenzimidazoles with Alkynes

    Org. Lett. 2017, 19, 1702-1705

    José M. Villar, Jaime Suárez, Jesús A. Varela, Carlos Saá

  4. [2 + 1] Cycloaddition of Catalytic Ruthenium Vinyl Carbenes: A Stereoselective Controlled Access to (Z)- and (E)-Vinyl Epoxypyrrolidines

    ACS Catalysis 2017, 7, 992-996

    Damián Padín, Fermín Cambeiro, Martín Fañanás-Mastral, Jesús A. Varela, Carlos Saá

  1. Metal-Catalyzed Cyclizations to Pyran and Oxazine Derivatives

    Synthesis 2016, 48, 3470-3478

    Jesús A. Varela, Carlos Saá

  2. Iron(III)-Catalyzed Ring-Closing Carbonyl–Olefin Metathesis

    Angew. Chem. Int. Ed 2016, 55, 10960-10961

    Carlos Saá

  3. Tandem Long Distance Chain-Walking/Cyclization via RuH2(CO)(PPh3)3/Brønsted Acid Catalysis: Entry to Aromatic Oxazaheterocycles

    Org. Lett. 2016, 18, 642-645

    Rodrigo Bernárdez, Jaime Suárez, Martín Fañanás-Mastral, Jesús A. Varela, Carlos Saá

  1. DFT and Kinetic Monte Carlo Study of TMS-Substituted Ruthenium Vinyl Carbenes: Key Intermediates for Stereoselective Cyclizations

    ACS Catalysis 2015, 5, 6255-6262

    Fermín Cambeiro, Emilio Martínez-Núñez, Jesús A. Varela, Carlos Saá

  2. Catalytic Cyclization of o-Alkynyl Phenethylamines via Osmacyclopropene Intermediates: Direct Access to Dopaminergic 3-Benzazepines

    Angew. Chem. Int. Ed. 2015, 54, 13357-13361

    Andrea Álvarez-Pérez, Carlos González-Rodríguez, Cristina García-Yebra, Jesús A. Varela, Enrique Oñate, Miguel A. Esteruelas, Carlos Saá

  3. Rh(III)-catalyzed [5+1] oxidative cycloaddition of arylguanidines with alkynes: a novel access to C4-disubstituted 1,4-dihydroquinazolin-2-amines

    Chem. Commun 2015, 51, 15157-15160

    Ana Cajaraville, Jaime Suárez, Susana López, Jesús A. Varela, Carlos Saá

  4. Nucleophilic Addition of Amines to Ruthenium Carbenes: ortho-(Alkynyloxy)benzylamine Cyclizations towards 1,3-Benzoxazines

    Angew. Chem. Int. Ed. 2015, 54, 2724-2728

    Carlos González-Rodríguez, José R. Suárez, Jesús A. Varela, Carlos Saá

  1. Ruthenium Hydroxycarbenes as Key Intermediates in Cycloisomerization and Decarbonylative Cyclization of Terminal Alkynals

    Organometallics 2014, 33, 3474-3480

    María Batuecas, Miguel A. Esteruelas, Cristina García-Yebra, Carlos González-Rodríguez, Enrique Oñate, Carlos Saá

  2. One-step Chemoselective Conversion of Tetrahydropyranyl Ethers to Silyl-Protected Alcohols

    RSC Adv. 2014, 4, 14475-14479

    Julián Bergueiro, Javier Montenegro, Carlos Saá, Susana López

  3. Catalytic Transformations of Alkynes via Ruthenium Vinylidene and Allenylidene Intermediates

    Top. Organomet. Chem. 2014, 48, 237-288

    Jesús A. Varela, Carlos González-Rodríguez, Carlos Saá

  4. Vinyl Dihydropyrans and Dihydrooxazines from Cyclizations of Catalytic Ruthenium Carbenes Derived from Alkynals and Alkynones

    Angew. Chem. Int. Ed. 2014, 53, 5959-5963

    Fermín Cambeiro, Susana López, Jesús A. Varela, Carlos Saá

  5. Dihydrobiphenylenes through Ruthenium-Catalyzed [2+2+2] Cycloadditions of ortho-Alkenylarylacetylenes with Alkynes

    Angew. Chem. Int. Ed. 2014, 53, 1841-1844

    Silvia García-Rubín, Carlos González-Rodríguez, Cristina García-Yebra, Jesús A. Varela, Miguel A. Esteruelas, Carlos Saá

  1. Rh(III)-Catalyzed Tandem C-H Allylation and Oxidative Cyclization of Anilides: A New Entry to Indoles

    Org. Lett. 2013, 15, 4576-4579

    Ana Cajaraville, Susana López, Jesús A. Varela, Carlos Saá

  1. Tandem Brönsted Acid Promoted and Nazarov Carbocyclizations on Enyne Acetals to Hydroazulenones

    Angew. Chem. Int. Ed. 2012, 51, 12316-12320

    Luz Escalante, Carlos González-Rodríguez, Jesús A. Varela, Carlos Saá

  2. Formation of Indoles, Dihydroisoquinolines, and Dihydroquinolines by Ruthenium-Catalyzed Heterocyclizations

    Synthesis 2012, 44, 3285-3295

    Alejandro Varela-Fernández, Jesús A. Varela, Carlos Saá

  3. Synthesis of 11-cis-Retinoids by Hydrosilylation-Protodesilylation of an 11,12-Didehydro Precursor: Easy Access to 11- and 12-Mono- and11, 12-Dideuteroretinoids

    Chem. Eur. J. 2012, 18, 14100-14107

    Julián Bergueiro, Javier Montenegro, Carlos Saá, Susana López

  4. Cross-Coupling Reactions of Organosilicon Compounds in the Stereocontrolled Synthesis of Retinoids

    Chem. Eur. J. 2012, 18, 4401-4410

    Julián Bergueiro, Javier Montenegro, Fermín Cambeiro, Carlos Saá, Susana López

  5. Cyclization by Catalytic Ruthenium Carbene Insertion into Csp3-H Bonds

    Angew. Chem. Int. Ed. 2012, 51, 723-727

    Fermín Cambeiro, Susana López, Jesús A. Varela, Carlos Saá

  1. Ru-Catalyzed Heteroannulation to Indoles, Dihydroisoquinolines, and Dihydroquinolines

    Synfacts 2011, 1165

    Alejandro Varela-Fernández, Jesús A. Varela, Carlos Saá

  2. Dehydrative Cyclization of Alkynals: Vinylidene Complexes with the Cß Incorporated into Unsaturated Five- or Six-Membered Rings

    Angew. Chem. Int. Ed. 2011, 50, 9712 –9719

    María Batuecas, Luz Escalante, Miguel A. Esteruelas, Cristina García-Yebra, Enrique Oñate, Carlos Saá

  3. Ruthenium-Catalyzed Cycloisomerization of Aromatic Homo- and, Bis-Homopropargylic Amines/Amides: Formation of Indoles, Dihydroisoquinolines and Dihydroquinolines

    Adv. Synth. Catal. 2011, 353, 1933 – 1937

    Alejandro Varela-Fernández, Jesús A. Varela, Carlos Saá