ECTS credits ECTS credits: 6
ECTS Hours Rules/Memories Student's work ECTS: 99 Hours of tutorials: 3 Expository Class: 24 Interactive Classroom: 24 Total: 150
Use languages Spanish, Galician
Type: Ordinary Degree Subject RD 1393/2007 - 822/2021
Center Faculty of Medicine and Dentistry
Call: First Semester
Teaching: Sin Docencia (En Extinción)
Enrolment: No Matriculable (Sólo Planes en Extinción)
To know the cells as the basic units on which the structure and function of the human body is based to ensure a correct understanding of the modifications that occur in pathological states.
INTEREST OF THE COURSE IN THE DEGREE OF MEDICINE
It is fundamental for any future doctor to acquire a deep knowledge of cell biology and human genetics (structure, function, and behavior of cells), since in today's medicine the different pathologies are considered as cellular and molecular dysfunctions.
PART I: CYTOLOGY
I. THE CELL: BASIC UNIT OF LIFE (1 hour)
Lesson 1: The cell: basic unit of life. Special cytology.
II. CELL SURFACE AND BIOMEMBRANES: PLASMA MEMBRANE. (6 hours)
Lesson 2: Extracellular environment
Lesson 3: Plasma Membrane: Concept and Generalities
Lesson 4: Mechanisms of permeability and transport of micromolecules through the membrane.
Lesson 5: Transport of macromolecules through the membrane: Endocytosis and exocytosis.
Lesson 6: Cell surface specializations.
III. HYALOPLASM AND SKELETON: CELLULAR FORM AND MOVEMENT (4 hours)
Lesson 7: Hyaloplasm. Concept and chemical composition. Cytoskeleton: concept and generalities.
Lesson 8: Microfilaments.
Lesson 9: Intermediate Filaments.
Lesson 10: Microtubules.
IV. CELL COMPARTMENT (6 hours)
Lesson 11: Endoplasmic reticulum.
Lesson 12: Golgi Apparatus.
Lesson 13: Lysosomes and Endosomes
Lesson 14: Peroxisomes and Mitochondria.
V. ORGANS THAT PROCESS INFORMATION: NUCLEUS AND RIBOSOMES (3 hours)
Lesson 15: Cellular nucleus: general characteristics
Lesson 16: Core in interface
Lesson 17: Nucleolus: structure and function Ribosomes. Proteasome.
VI. CELL CYCLE AND CELL DIVISION. (3 hours)
Lesson 18: The cell cycle.
Lesson 19: Mitosis.
Lesson 20: Meiosis.
PART II: GENETICS
VII. ORGANIZATION, TRANSMISSION AND EXPRESSION OF HEREDITARY MATERIAL: INHERITANCE PATTERNS (6 hours)
Lesson 21: Organization of the genome.
Lesson 22: Mendelian Inheritance Patterns
Lesson 23: Atypical inheritance patterns.
Lesson 24: Polygenic and Multifactorial Inheritance
VIII. GENETIC MATERIAL CHANGES (6 hours).
Lesson 25: Genetic variation: Mutation.
Lesson 26: Chromosomal alterations.
Lesson 27: Mendelian populations.
Lesson 28: Polymorphisms.
Lesson 29: Genetic counselling.
Lesson 30: Genetic Basis of Cancer.
INTERACTIVE LESSONS
Laboratory practices: (12 hours)
P1: The optical microscope: Nomenclature and instructions for use
P2-3: Basic techniques: Sample preparation and staining I: free cells
P4-5: Basic techniques: Sample preparation and staining II: associated cells
P6: The cell: general characteristics and cell surface.
P7: Microscopic study of cytoskeleton.
P8: Microscopic study of organelles I.
P9: Microscopic study of organelles II.
P10: Microscopic study of mitosis and meiosis
P11- Nucleus, metaphasic chromosomes and chromatin
P12: ABO system. Determination of blood group
P13-P14: Academic group work
P15-P16: Basics and application of PCR
Seminars (4 hours)
S1: Origin of the cell.
S2: Cell death: Necrosis and Apoptosis
S3: Genetic problems and games
S4: Genetic problems and games
BASIC BIBLIOGRAPHY.
1 CALVO A. Biología Celular Biomédica. 1ª ed. Elsevier; 2015.
2 JORDE LB, CAREY JC, BAMSHAD MJ. Genética Médica. 6ª ed. Elsevier; 2020.
3 KARP G. Biología celular y molecular. Conceptos y experimentos. 8ª ed. McGraw-Hill; 2019.
4 NUSSBAUM RL, MCINNES RR, WILLARD HF. THOMPSON & THOMPSON. Genética en Medicina. 8ª Ed. Elsevier Masson; 2016.
5 PANIAGUA R. Biología celular y molecular. 4ª ed. McGraw-Hill; 2017.
6 TURNPENNY P, ELLARD S, CLEAVER R. EMERY. Elementos de genética médica y genómica 16ª ed. Elsevier. 2022.
COMPLEMENTARY BIBLIOGRAPHY:
1 ALBERTS B, BRAY D, LEWIS J, RAFF M, ROBERTS K, WATSON J. Biología Molecular de la Célula. Omega; 2016.
2 KIERSZENBAUM AL, TRES LL. Histología y Biología Celular. Introducción a la anatomía patológica. 5ª ed. Elsevier; 2020.
3 LODISH H, BERK A, KAISER CA, KRIEGER M, BRETSCHER A, PLOEGH H, AMON A, SCOTT MP. Biología Celular y Molecular. 7ª ed. Médica Panamericana; 2021.
4 PIERCE BA. Genética: un enfoque conceptual. 5ª ed. Médica Panamericana; 2016.
ADDITIONAL RESOURCES
1 VILLAR CHEDA, B. LÓPEZ LÓPEZ, A. Hialoplasma e citoesqueleto: forma e movemento celular. 2020. Unidades didácticas USC. https://dx.doi.org/10.15304/9788417595555.
2 VILLAR CHEDA, B Xenética humana: conceptos básicos aplicados a ciencias da saúde. 2021. Colección: Esenciais USC.
GENERAL COMPETENCIES (GC)
This course helps to reinforce many of the basic skills of the degree:
GC5. Recognizing one's own limitations and the need to maintain and update one's professional competence, paying special attention to the autonomous learning of new knowledge and techniques and to motivation for quality.
GC6. To develop professional practice with respect to other health professionals, acquiring teamwork skills.
GC7 Understanding and recognizing the normal structure and function of the human body, at the molecular, cellular, tissue, organic and systems level, in the different stages of life and in both sexes.
GC9. Understand and recognize the effects, mechanisms and manifestations of disease on the structure and function of the human body,
GC23 Communicating effectively and clearly, both orally and in writing.
GC31 Knowing, critically evaluating and understand how to use clinical and biomedical information sources to obtain, organize, interpret and communicate scientific and health information.
GC36 To be able to formulate hypotheses, to collect and to value of form critical the information for the resolution of problems, following the scientific method.
GC37 To acquire the basic formation for the research activity.
MODULE I SPECIFIC COMPETENCES (MISC)
MISC.01 To know the structure and function of cells: Cellular membranes and morphological differentiations of cellular communication. The cytoskeleton as responsible for the shape and movement of cells. The endomembrane system and the energetic organelles
MISC.06 Cellular Communication
MISC.08.- Cell cycle.
MISC.09.- Cell differentiation and proliferation.
MISC.10.- Gene information, expression, and regulation.
MISC.11.- Inheritance: Genetic information, expression and regulation and its transmission through the different models of inheritance
MISC.18.- Handling of material and basic laboratory techniques.
MISC.20.- Recognize with macroscopic and microscopic methods and image techniques the morphology and structure of tissue, organs, and systems.
The course will have a virtual classroom at the Campus Virtual in which students will be able to have didactic material and digitalized images of support. In addition, a public tutoring forum will be established in the Campus Virtual. Other programs (MS Teams, Forms,...) will be used if they are deem appropriate and if circumstances allow.
The final tests will be IN-PERSON
The evaluation of the course will assess the knowledge, skills, and abilities demonstrated by students during the current academic year (grades obtained in previous years will not be carried over).
The evaluation system will apply to both opportunities.
The evaluation of the expository content will account for up to 80% of the final grade, and the interactive part will account for at least the remaining 20%.
The evaluation will be conducted in two parts (20% of the grade) assessing interactive content, and a final exam (80% of the grade).
The partial evaluation is based on the completion of different activities, which will be scheduled and announced on the virtual campus. The completion of these activities will be in person.
The final evaluation exam will consist of a test adapted to the specific circumstances of the subject, which may include different types of questions (such as multiple-choice tests with a single answer, brief questions, essay-type questions, clinical cases, problems, ...) and formats (written, oral, multimedia, ...).
The different tests and/or activities may be replaced by online exams, either synchronous or asynchronous, using the resources of institutional platforms (Virtual Classroom-Moodle and Microsoft Teams,...)
The requirements to pass the course are obtaining at least 50% of the score on the final exam, as well as having attended 80% of the interactive activities in previous courses.
"In cases of fraudulent completion of exercises or exams, the provisions outlined in the academic performance evaluation and grade review regulations for students will apply."
PRESENTIAL WORK IN THE CLASSROOM: 4 Hours
Tutorials in small groups or individualized: 2
Exams to be taken: 2
STUDENT PERSONAL WORK: 90 Hours
Individual study: 75
Preparation of internship reports: 5
Elaboration of works: 10
It is recommended to use notes taken in previous years during classes and supplement them with the available teaching materials in the virtual campus and/or with the recommended bibliography, available through the library both in paper format and through digital access. It is advisable to study the contents daily and to use the individual tutorials and the public tutorial forum to solve doubts.
It is advisable to carry out a self-evaluation process, guided by the results of the continuous assessment, to learn how to critically evaluate the level of one's own knowledge and skills.
Juan Andres Parga Martin
- Department
- Morphological Science
- Area
- Human Anatomy and Embryology
- juan.parga [at] usc.es
- Category
- Professor: University Lecturer
| 12.19.2025 12:00-14:30 | Grupo de examen | Medicina-Aula 10 |
| 12.19.2025 12:00-14:30 | Grupo de examen | Medicine-Classroom 2 |
| 12.19.2025 12:00-14:30 | Grupo de examen | Medicine-Classroom 3 |
| 12.19.2025 12:00-14:30 | Grupo de examen | Medicine-Classroom 4 |
| 12.19.2025 12:00-14:30 | Grupo de examen | Medicine-Classroom 5 |
| 12.19.2025 12:00-14:30 | Grupo de examen | Medicine-Classroom 6 |
| 12.19.2025 12:00-14:30 | Grupo de examen | Medicine-Classroom 7 |
| 12.19.2025 12:00-14:30 | Grupo de examen | Medicine-Classroom 8 |
| 12.19.2025 12:00-14:30 | Grupo de examen | Medicine-Classroom 9 |
| 06.10.2026 09:30-12:00 | Grupo de examen | Medicine-Classroom 4 |
| 06.10.2026 09:30-12:00 | Grupo de examen | Medicine-Classroom 5 |
| 06.10.2026 09:30-12:00 | Grupo de examen | Medicine-Classroom 7 |
| 06.10.2026 09:30-12:00 | Grupo de examen | Medicine-Classroom 8 |