Aqueous synthesis and in-situ rapid screening of amphiphilic polymers

The present invention relates to screening methods that use novel amphiphilic polymers conjugated with biomolecules such us DNA, RNA or siRNA. The novel methods aloww a faster and more flexible screening of suitable transfecting agents and delivering biomolecules of interest. The application also dicloses novel transfection agents identified folloeing the screening method.
  • Reagents with excellent transfection activity in presence of different membrane models
  • Flexible and efficient in situ screening
  • Process done entirely in aqueous media
  • No intermediate purification
 
Grupo de investigación: