ECTS credits ECTS credits: 6
ECTS Hours Rules/Memories Student's work ECTS: 99 Hours of tutorials: 3 Expository Class: 24 Interactive Classroom: 24 Total: 150
Use languages Spanish, Galician
Type: Ordinary Degree Subject RD 1393/2007 - 822/2021
Departments: Biochemistry and Molecular Biology
Areas: Biochemistry and Molecular Biology
Center Faculty of Pharmacy
Call: Second Semester
Teaching: Sin docencia (Extinguida)
Enrolment: No Matriculable
- To study the processes responsible for the maintenance of genetic information and its regulation.
- To know the main techniques used in molecular biology to understand the latest scientific advances.
- To know the main metabolic pathways and their relationship to some diseases. Get an integrated view of metabolism and its regulation.
Programme of lectures:
The lectures will take place in 30 sessions of one hour each.
Item 1. Maintenance of genetic information.
Item 2. Regulation of gene expression.
Item 3. Recombinant DNA technology.
Item 4. Carbohydrate metabolism and its regulation.
Item 5. Lipid metabolism and its regulation.
Item 6. Metabolism of amino acids and related molecules.
Item 7. Integration and regulation of metabolism.
Interactive class schedule:
The lectures are supplemented by 12 hours of interactive classes, grouped into six sessions of 2 hours each. The students will discuss and resolve questions and problems related to the subject, to be worked on previously. This material will be available either on the website of the course or will be provided by the teacher.
Program of practical lessons:
Laboratory practical classes will be held in 3 sessions of 4 hours and a test at the end of them.
Practice 1. Transformation of E. coli with recombinant plasmid DNA.
Practice 2. Identification of colonies of E. coli with recombinant plasmid
Practice 3. Digestion of a plasmid with restriction enzymes. Separation and quantification of DNA fragments in agarose gels.
Practice 4. Intermediary metabolism
Basic Bibliography
- Bioquímica. Conceptos esenciales. Feduchi y col. Editorial Médica Panamericana, 2ª ed.,2015.
- Lehninger. Principios de Bioquímica. Nelson y Cox. Editorial Omega. 6ª ed., 2015.
- Bioquímica. Curso básico. Stryer, Berg y Tymoczko. Editorial Reverté, S.A., 2014
Complementary Bibliography :
- Fundamentos de Bioquímica metabólica. Teijón Rivera y Blanco Gaitán. Editorial Tébar Flores S.L., 4ª edición, 2017
- Fundamentos de Bioquímica. Voet, Voet, Pratt. Editorial Médica Panamericana. 4ª ed., 2016.
- Biología Molecular de la célula. Alberts, Bray, Lewis, Raff, Roberts y Watson. Editorial Omega. 6ª ed., 2016.
- Bioquímica. Mathews, Van Holde y Anthony-Cahill. Ed. Pearson, 2013
- Texto ilustrado e interactivo de Biología Molecular e ingeniería genética. Angel Herráez. Editorial Elsevier, 2ª ed., 2012.
- Bioquímica. Fundamentos para Medicina y Ciencias de la Vida. Werner Müller-Esterl. Editorial Reverté. 2008.
- Bioquímica y Biología Molecular para ciencias de la salud. Lozano y col. Editorial McGraw-Hill-Interamericana. 3ª ed., 2005.
- Bioquímica. Libro de texto con aplicaciones clínicas. Devlin. Editorial Reverté, S.A., 4ª ed., 2004.
General skills:
3. Learn to apply the scientific method and acquire skills in handling legislation, sources of information, literature, development of protocols and other aspects considered necessary for the design and critical assessment of preclinical and clinical trials.
10. Design, apply and evaluate reagents, methods and clinical analytical techniques, knowing the basic fundamentals of clinical analyzes and the characteristics and contents of laboratory diagnostic opinions.
13. Develop communication and information skills, oral and written, to deal with patients and users of the facility where play their work.
14. Promote the work and collaboration capabilities in multidisciplinary teams and those associated with other health professionals.
Specific skills:
B01 To know the transformations of biomolecules in the cell.
B03 To estimate the biological risks associated with the use of chemicals and laboratory processes involved.
B05 Develop skills to identify therapeutic targets and production of biotechnological drugs, as well as use of gene therapy.
B07 To know the properties of cell membranes and the distribution of drugs.
B09 To know the main metabolic pathways involved in the degradation of drugs.
Transversal skills:
CI03 Basic general knowledge.
CI05 Oral and written communication in their own language.
CS01 Ability to apply knowledge in practice.
CS03 Capacity to learn.
A) Large Group Lectures: Lesson taught by the teacher in which the theoretical contents of the subject are presented. The USC virtual platform will serve as a support and complement to theoretical teaching.
Scenario 1: Presence in the classroom
Scenario 2: Synchrotic Telematics Teaching
Scenario 3: Synchron/Asynchronous Telematics Teaching
B) Small Group Interactive Classes: Theoretical/practical class in which applications of theory, problems, exercises are proposed and solved. The student actively participates in these classes in different ways: delivery of exercises to the teacher, resolution of exercises in the classroom, etc. Written evidence on specific sections is included. Attendance at these interactive classes is mandatory for continuous evaluation.
Scenario 1: Presence in the classroom
Scenario 2: Presence in the classroom
Scenario 3: Synchron/Asynchronous Telematics Teaching
C) Very small group tutoring: Tutoring scheduled by the teacher. Activities are proposed such as monitoring the degree of learning and understanding of the subject, clarifying doubts about theory or practices, problems, exercises, readings or other proposed tasks.
Scenario 1: Presence in the classroom
Scenario 2: Presence in the classroom
Scenario 3: Synchron/Asynchronous Telematics Teaching
D) Practical laboratory classes: The student acquires the skills of a laboratory and consolidates the knowledge acquired in the theory classes. For these practices, the student will have a hyphen. The student will perform all the practices individually, or in small groups, collecting in the script the results that proceed, presenting them to the teacher at the end of each session. Attendance in these practical classes is mandatory.
Scenario 1: 100% In-person synchronous practices in the laboratory. Groups of 20 students
Scenario 2: 50% In-person synchronous practices in the lab, 50% Virtual asynchronous practices. Groups of 10 students
Scenario 3: 100% Virtual Practices (synchronous or asynchronous or a combination of both). Groups of 20 students (synchronous)
E) USC virtual platform as a support and complement to theoretical-practical teaching and as an important element of communication with the student. It will make available to students the theoretical and practical resources necessary for the study of the subject.
1. The evaluation in the two calls of the academic year and in the 3 scenarios will consist of three parts: theoretical part, practical part and part corresponding to the interactive classes.
For scenarios 2 and 3, MS Teams and/or Moodle platforms will be used for evaluation.For cases of fraudulent conduct of exercises or tests, the "Regulation of student performance evaluation and review of qualifications" will apply.
2. The theoretical examination complementary to the continuous evaluation shall be 70% of the final qualification (maximum of 7 points). The examination will preferably be of a mixed type, with test-type questions to cover all the fundamental parts of the subject matter, and with short and concrete questions, which allow to assess the development of reasoning and the assimilation of matter. It is necessary that the qualification obtained in this examination exceeds 45% (3.2) of the maximum (7) corresponding to that paragraph in order to assess the rest of the paragraphs.
3. The evaluation of the laboratory practical part will mean 10% (up 1 point) of the final grade. This assessment will include the work done by the student in the laboratory as well as the understanding of experimental results, to be conducted through a written test consisting of short questions.
Assistance to all the practical sessions and the final written test is mandatory to pass the subject of Biochemistry II.
Mark for the practical laboratory part will be maintained only during the two following academic years in the case of failing the course.
4. The evaluation of interactive classes will be 20% (maximum 2 points). The final grade will be established taking into account: active student participation in class, proposed activities, notes for written evidence on specific sections can be made, etc. The rating for this Section applies only to the academic year in which they are made.
5. In the 2 nd call of the academic year, studens will only be examined of the theory section, preserving the appraisal for interactive and practical sections. The maximum score of this exam and the required minimum is the same as described for the first call.
6. The student must obtain five out of ten to pass the course.
7. The evaluation of the competences acquired in the subject will be done through the following ways:
Theoretical exam: B01, B05, B07, B09, CI03, CI05, CS03
Laboratory classes: 3, 10, 13, 14, B03, CI03, CI05, CS01, CS03
Interactive classes: 3, 10, 13, 14, B01, B05, B07, B09, CI03, CS01, CS03
FACE IN THE HALL WORK HOURS
Large-group lectures 30
Small group interactive classes 12
Very small group tutorials 2
Labs 12
Testing and revision 4
Total operating hours in the
classroom or laboratory 60
STUDENT PERSONNEL WORK HOURS
Individual self-study or group 60
Solving exercises, or other work 18
Orientation and resolution of questions 4
Preparation of laboratory work and
its reporting practices 4
Implementation and Review Exam 4
Total hours of personal work 90
Recommendations for evaluation:
The student should avoid simple memory effort, since it is not appropriate or sufficient, focusing on the study to achieve understanding, reasoning and relationship of the contents of the subject.
Regarding to the interactive classes, active participation in them, will allow the student a better understanding of many aspects explained in theory classes, which will facilitate the study for the final exam.
The use of USC virtual plattform is also highly recommended since students can ask their questions directly to the teacher via email. On this page will also be included materials such as outlines, summaries, problems or questions that help students to pass the subject.
Recommendations for Recovery:
Students are encouraged to attend the exam review where the teacher can explain what were the errors and to overcome them and in which parts of the subject must make a greater effort towards recovery.
It is also helpful to the student try to resolve all issues that have been proposed during the course, as well as those contained in the recommended bibliography and go to tutorials to answer all questions with the help of the teacher
Contingency Plan:
For scenarios 2 and 3, MS Teams and/or Moodle platforms will be used for evaluation. For cases of fraudulent conduct of exercises or tests, the "Regulation of avaliation of the students performance and review of qualifications" will apply.
A) Large Group Lectures:
Scenario 2: Synchronous Telematics Teaching
Scenario 3: Synchronous/Asynchronous Telematics Teaching
B) Interactive classes:
Scenario 2: Presence in the classroom
Scenario 3: Synchronous/Asynchronous Telematics Teaching
C) Very small group tutoring:
Scenario 2: Presence in the classroom
Scenario 3: Synchronous/Asynchronous Telematics Teaching
D) Practical laboratory classes:
Scenario 2: 50% In-person synchronous practices in the lab, 50% Virtual asynchronous practices. Groups of 10 students
Scenario 3: 100% Virtual Practices (synchronous or asynchronous or a combination of both). Groups of 20 students (synchronous)
Maria Luz Perez-Paralle Mera
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- Phone
- 881816049
- luz.perez-paralle [at] usc.es
- Category
- Professor: University Lecturer
Leopoldo Oscar Garcia Martin
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- Phone
- 881814935
- leopoldooscar.garcia [at] usc.es
- Category
- Professor: University Lecturer
Marcelina Abad Caeiro
Coordinador/a- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- Phone
- 881814931
- marcelina.abad [at] usc.es
- Category
- Professor: University Lecturer
María Paz García Martínez
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- Phone
- 881814908
- paz.garcia [at] usc.es
- Category
- Professor: University Lecturer
| Monday | |||
|---|---|---|---|
| 09:30-10:30 | Grupo C/CLE_03 | Spanish | 5035 Virtual classroom |
| 15:00-16:00 | Grupo B/CLE_02 | Spanish | 5035 Virtual classroom |
| Tuesday | |||
| 09:30-10:30 | Grupo C/CLE_03 | Spanish | 5035 Virtual classroom |
| 19:00-20:00 | Grupo B/CLE_02 | Spanish | 5035 Virtual classroom |
| Wednesday | |||
| 09:30-10:30 | Grupo C/CLE_03 | Spanish | 5035 Virtual classroom |
| 15:00-16:00 | Grupo B/CLE_02 | Spanish | 5035 Virtual classroom |
| Thursday | |||
| 09:30-10:30 | Grupo C/CLE_03 | Spanish | 5035 Virtual classroom |
| 19:00-20:00 | Grupo B/CLE_02 | Spanish | 5035 Virtual classroom |
| Friday | |||
| 09:30-10:30 | Grupo C/CLE_03 | Spanish | 5035 Virtual classroom |