ECTS credits ECTS credits: 6
ECTS Hours Rules/Memories Student's work ECTS: 99 Hours of tutorials: 3 Expository Class: 24 Interactive Classroom: 24 Total: 150
Use languages Spanish, Galician
Type: Ordinary Degree Subject RD 1393/2007 - 822/2021
Departments: Physical Chemistry
Areas: Physical Chemistry
Center Faculty of Pharmacy
Call: Second Semester
Teaching: Sin docencia (Extinguida)
Enrolment: No Matriculable
Study of all the experimental techniques which, using a complex instrumentation in most cases, allows to obtain a series of data that, in addition to the analytical determination of a pharmaceutical substances level can be reached also to know their structural characteristics.
-Spectroscopic methods:
Unit 1: Introduction. Item 2: Visible-UV spectrophotometry. Item 3: Fluorescence spectrophotometry.
-Electrochemical Methods:
Item 4: Technical conductivity. Item 5: PotentiometricTechniques.
-Methods of Separation:
Topic 6: Introduction to Chromatography. Item 7: Gas Chromatography. Instrumentation. Topic 8: Liquid Chromatography: General. Adsorption and Liquid Chromatography Sharing. Item 9: Liquid Chromatography: Exclusion Chromatography. Ion Chromatography. Liquid Chromatography Instrumentation. Item 10:Flat Liquid Chromatography: Thin Layer Chromatography.
Item 11: Supercritical Fluid Chromatography. Item 12: Electrophoresis and Isoelectric focusing. Item 13: Mass Spectrometry.
Program of practical classes:
Practice 1. Quantitative analysis by visible-ultraviolet spectrophotometry: Beer-Lambert law
Practice 2. Potentiometric titration of a weak acid and approximate determination of its pKa.
Practice 3. Analyzing samples by gas chromatography
basic
• Skoog, D. A., Holler, F. J. Nieman, T. A. Principles of Instrumental Analysis, (Spanish translation of Principles of Instrumental Analysis, by Maria C. Martin Gomez and others), McGraw-Hill, Madrid, 2003.
• Ewing, G. W. Instrumental Methods of Chemical Analysis, (Spanish translation of the English original Instrumental Methods of Chemical Analysis, 4th ed., McGraw-Hill, 1975, by Eva Estrada Meza), Mc Graw-Hill, Mexico, 1978.
These two general books can be used virtually throughout the course, it is no longer included in the bibliography for each chapter and covering most topics of the course with a clear and adequate material for students who are consulted.
Complementary
• Christian, G. D.; O'Reilly, J. E. Instrumental Analysis, 2nd ed., Allyn and Bacon, Boston, 1986.
• Ewing, G. W. Analytical instrumentation handbook, Marcel Dekker, New York, 1990.
• Miñones Trillo, J. Instrumental Techniques Manual, 2 volumes, editor Circle Universe, Barcelona, 1978.
• Valls, O., del Castillo, B. Instrumental techniques of Pharmacy and Health Sciences, 4th ed., Piros Editions, Barcelona, 1998.
• Delahay, P. Instrumental Analysis (Physicochemical methods of analysis), (Spanish translation of Instrumental Analysis, Mc Millan, New York, 1963.
General competences.
1. Identify, design, obtain, analyze, control and produce drugs and medicines, as well as other products and raw materials of health interest for human or veterinary use.
2. To evaluate the therapeutic and toxic effects of substances with pharmacological activity.
3. To know how to apply the scientific method and to acquire skills in the management of legislation, sources of information, bibliography, elaboration of protocols and other aspects considered necessary for the design and critical evaluation of preclinical and clinical trials.
10. Design, apply and evaluate clinical analytical reagents, methods and techniques, knowing the basics of clinical analyzes and the characteristics and contents of laboratory diagnostic opinions.
13. Develop communication and information skills, both oral and written, to deal with patients and users of the center where they carry out their professional activity.
14. To promote the capacity of work and collaboration in multidisciplinary teams and those related to other health professionals.
16. Recognize one's own limitations and the need to maintain and update professional competence, with particular emphasis on self-learning of new knowledge based on available scientific evidence.
General competences.
1. Identify, design, obtain, analyze, control and produce drugs and medicines, as well as other products and raw materials of health interest for human or veterinary use.
2. To evaluate the therapeutic and toxic effects of substances with pharmacological activity.
3. To know how to apply the scientific method and to acquire skills in the management of legislation, sources of information, bibliography, elaboration of protocols and other aspects considered necessary for the design and critical evaluation of preclinical and clinical trials.
10. Design, apply and evaluate clinical analytical reagents, methods and techniques, knowing the basics of clinical analyzes and the characteristics and contents of laboratory diagnostic opinions.
13. Develop communication and information skills, both oral and written, to deal with patients and users of the center where they carry out their professional activity.
14. To promote the capacity of work and collaboration in multidisciplinary teams and those related to other health professionals.
16. Recognize one's own limitations and the need to maintain and update professional competence, with particular emphasis on self-learning of new knowledge based on available scientific evidence.
Specific competences.
Q01. Identify, design, obtain, analyze and produce active ingredients, drugs and other products and materials of health interest.
Q02. Select appropriate techniques and procedures in the design, application and evaluation of reagents, methods and analytical techniques.
Q03. Carry out standard laboratory processes including the use of scientific synthesis and analysis equipment, including appropriate instrumentation.
Q05. Know the physico-chemical characteristics of the substances used for the manufacture of medicines.
Q09. To know the origin, nature, design, obtaining, analysis and control of medicines and sanitary products.
Q10. To know the principles and procedures for the analytical determination of compounds: analytical techniques applied to the analysis of water, food and the environment.
Transversal competences.
CI01. Capacity for analysis and synthesis.
CP01. Critical and self-critical capacity.
CS01. Ability to apply knowledge in practice.
CS08. Ability to work autonomously.
In the lectures the concepts and theoretical content of the subject will be given. They will be taught depending on the scenarios planned:
Scenario 1: They will be face-to-face in the classroom. For this we will help with new technologies for collective presentations, such as power point, videos, etc.
Scenario 2: They will be through synchronous telematic teaching (using MS Teams or Moodle).
Scenario 3: All teaching will be synchronous or asynchronous telematic.
The interactive seminar classes and tutorials will be dedicated to solving practical questions and problems and will be taught depending on the scenarios planned:
Scenario 1 and 2: They will be face-to-face in the classroom using the technologies described for the expository classes.
Scenario 3: All teaching will be synchronous or asynchronous telematics.
Laboratory practices.
Scenario 1: They will be face-to-face in the laboratory in groups of 20 students.
Scenario 2: 50% will be face-to-face in the laboratory, in groups of 10 students and the other 50% will be virtual asynchronous.
Scenario 3: They will be 100% virtual (synchronous or asynchronous or a combination of both). For the synchronous modality the groups will be 20 students.
The global grade will be the result of adding the grade obtained in three activities:
1º A final exam of theory and problems.
2º The continuous evaluation.
3º Laboratory practices and activities.
The final theory and problems exam will be graded on a maximum of 7.0 points, with 5.0 points corresponding to the theory exam and 2.0 points to the problems exam.
The theory exam will consist of several questions applied with several sections, some of which may be test type.
The examination of problems will consist of two or three problems with different sections.
It is an essential requirement to pass the subject to obtain a grade equal to or greater than 1.5 points on the theory exam and a grade equal to or greater than 0.6 points on the problem exam.
The continuous evaluation will consist of a series of tests that will be carried out during the hours of the interactive classes. These tests will consist of short questions, some of which may be of the test type, as well as a problem related to the recently explained subject. The maximum grade for continuous assessment is 2 points. Those repeating students who wish to do so, will be able to maintain the continuous assessment grade corresponding to the previous year without having to attend the interactive classes and the tests, being an indispensable requirement to have signed at the beginning of the term a document proving this commitment with the teacher in charge of the subject.
The realization of the practices by the student is an indispensable condition to be able to be evaluated of the subject. Likewise, it will be an indispensable requirement to pass an examination of said practices that will consist of a series of questions related to them. The contribution to the overall rating will be 0.5 points.
The activities will consist of carrying out different works, questions or problems that will be proposed as the subject is explained. The overall score will be 0.5 points.
The approved practices will be kept indefinitely, keeping the grade obtained. Repeating students who wish to do the practices again, must notify the teacher and they will have to do the corresponding exam again and pass it.
In the second opportunity of the call of the academic year, only the final exam of theory and problems will be carried out, keeping the marks corresponding to the practice and the continuous evaluation obtained. The maximum and minimum required grades will be the same as for the first opportunity.
The Theory and Problems exam will be carried out online or in person depending on the health situation in which we find ourselves.
The evaluation of the competences acquired in the subject will be done through the following ways:
. Interactive classes
- General Competences: 1; 2; 3; 13; 14 and 16.
- Specific Competences: Q02 and Q05.
- Transversal competences: CP01; CS08.
. Lab practices
- General Competences: 10 and 14.
- Specific Competences: Q01; Q02; Q03; Q05; Q09 and Q10.
- Transversal competences: CS01.
Exams
- General Competences: 1; 3 and 16.
- Specific Competences: Q02; Q05; Q09 Q10.
-Transversal competences: CI01; CP01; CS08
Class work:
-Large-group lectures: 30 hours
-Small group interactive classes: 14 hours
-Very small group tutorials: 2 hours
-Lab: 10 hours
-Testing and review: 4 hours
-Total operating hours for class attendance or in the laboratory: 60 hours
Personal work:
-Self-study individually or in group: 48 hours
-Resolution of exercises, or other work: 24 hours
-Guidance and resolution of questions: 2,5 hours
-Preparation of laboratory work and its reporting practices: 6,5 hours
-Implementation and Test Review: 9 hours
-Total hours of personal work: 90 hours
-Mathematical skills such as measurement errors.
-Understanding of statistics, graphs and interpretation functions.
-Exponential and logarithmic functions.
- Linear regression.
-Basic knowledge of physics.
- Physical Chemistry: There will be constant reference to the concepts studied in this area, which will serve as a starting point to address the merits of each of the techniques.
-Regular dedication to the study of matter (periods daily or every other day).
- As the study progresses it is necessary to resolve issues and problems raised in each chapter.
- Avoid entering a new chapter without having properly understood the above.
Maria Mercedes Parajo Montes
- Department
- Physical Chemistry
- Area
- Physical Chemistry
- Phone
- 881814212
- mmercedes.parajo [at] usc.es
- Category
- Professor: Temporary PhD professor
Arturo Baltasar Suarez Varela
Coordinador/a- Department
- Physical Chemistry
- Area
- Physical Chemistry
- Phone
- 881814912
- arturo.suarez [at] usc.es
- Category
- Professor: University Lecturer
Pedro Rodriguez Dafonte
- Department
- Physical Chemistry
- Area
- Physical Chemistry
- Phone
- 881814307
- pedro.rodriguez [at] usc.es
- Category
- Professor: University Lecturer
Carlos Manuel Estevez Valcarcel
- Department
- Physical Chemistry
- Area
- Physical Chemistry
- Phone
- 881814436
- carlosmanuel.estevez [at] usc.es
- Category
- Professor: University Lecturer
David Bugallo Ferrón
- Department
- Physical Chemistry
- Area
- Physical Chemistry
- david.bugallo.ferron [at] rai.usc.es
- Category
- Ministry Pre-doctoral Contract
| Monday | |||
|---|---|---|---|
| 09:00-10:00 | Grupo A/CLE_01 | Spanish | 5035 Classroom 2.1 Faculty of Politics |
| 19:00-20:00 | Grupo B/CLE_02 | Spanish | 5035 Classroom 2.1 Faculty of Politics |
| Tuesday | |||
| 09:00-10:00 | Grupo A/CLE_01 | Spanish | 5035 Classroom 2.1 Faculty of Politics |
| 19:00-20:00 | Grupo B/CLE_02 | Spanish | 5035 Classroom 2.1 Faculty of Politics |
| Wednesday | |||
| 09:00-10:00 | Grupo A/CLE_01 | Spanish | 5035 Classroom 2.1 Faculty of Politics |
| 19:00-20:00 | Grupo B/CLE_02 | Spanish | 5035 Classroom 2.1 Faculty of Politics |
| Thursday | |||
| 09:00-10:00 | Grupo A/CLE_01 | Spanish | 5035 Classroom 2.1 Faculty of Politics |
| 19:00-20:00 | Grupo B/CLE_02 | Spanish | 5035 Classroom 2.1 Faculty of Politics |
| Friday | |||
| 09:00-10:00 | Grupo A/CLE_01 | Spanish | 5035 Classroom 2.1 Faculty of Politics |
| 19:00-20:00 | Grupo B/CLE_02 | Spanish | 5035 Classroom 2.1 Faculty of Politics |