ECTS credits ECTS credits: 6
ECTS Hours Rules/Memories Hours of tutorials: 1 Expository Class: 32 Interactive Classroom: 24 Total: 57
Use languages Spanish, Galician
Type: Ordinary Degree Subject RD 1393/2007 - 822/2021
Departments: Biochemistry and Molecular Biology
Areas: Biochemistry and Molecular Biology
Center Faculty of Biology
Call: Second Semester
Teaching: Sin docencia (Extinguida)
Enrolment: No Matriculable | 1st year (Yes)
To
- Identify and distinguish the structure, properties and function of biomolecules.
- Identify the relationship between the structure and function of biomolecules.
- Apply the principles of thermodynamics to biological systems.
- Distinguish the different classes of enzymes and their catalysis mechanisms, as well as the principles of enzyme regulation.
- Know the different components of biological membranes and their functionality.
- Know how to carry out purification processes and analysis of biomolecules.
- Know how to measure enzyme activities.
All the different activities will be face-to-face.
MAGISTER CLASSES (30 hours)
INTRODUCTION
• Unit 1. Biochemical science. Molecular design of life (2h).
BIOLOGICAL STRUCTURE AND FUNCTION OF BIOMOLECULES
• Unit 2. Carbohydrates (2h).
• Unit 3. Lipids (2h).
• Unit 4. Nucleotides and nucleic acids (2 h).
• Unit 5. Amino acids, peptide bond and peptides (2 h).
• Unit 6. Three-dimensional structure and functionality of proteins (3h).
• Unit 7. Function of proteins. Myoglobin and hemoglobin (3h).
ENZYMOLOGY
• Unit 8. Enzymes: structure and function (3h).
• Unit 9. Enzymatic reaction. Kinetics of the enzymatic reaction (3h).
• Unit 10. Inhibition and regulation of the enzymatic reaction (3h).
INTRODUCTION TO METABOLISM AND ITS REGULATION
• Unit 11. Bioenergetics: energy exchanges and high energy level compounds (2h).
• Unit 12. Biological membranes and metabolic mediated transport (1h).
• Unit 13. Introduction to metabolism and its regulation. (2h)
INTERACTIVE CLASSES / PRACTICAL CLASS PROGRAM (14 h)
• PRACTICE 1. Obtaining extracts from animal tissue (calf liver) and fractionation of cellular organelles. Preparation of reagents (2.5 h).
• PRACTICE 2. Obtaining and analysis of DNA from eukaryotic cell nuclei. Electrophoretic analysis on agarose gels (3 h).
• PRACTICE 3. Quantitative determination of proteins. Lowry's method (2.5 h).
• PRACTICE 4. Isolation and quantification of hepatic glycogen (3 h).
• PRACTICE 5. Enzymology: kinetics and enzyme inhibition (3 h).
INTERACTIVE CLASSES PROGRAM / SEMINARS (10 h)
• Seminar 1: carbohydrates and lipids (2h)
• Seminar 2: amino acids and proteins (2h)
• Seminar 3: enzymology I. Enzymatic activity (2h)
• Seminar 4: enzymology II. Enzymatic inhibition (2h)
• Seminar 5: biological and bioenergetic membranes (2h)
TUTORIALS (1h).
It is placed at the beginning of the course to explain the development of the subject and the evaluation table.
Basic
• Berg, J.M., Tymoczko, J.L. & Stryer L., 2015. Bioquímica con aplicaciones clínicas. 7ª ed. Barcelona: Reverté.
• Mathews, C.K., Van Holde, K.E. & Anthony-Cahill, S.J., 2013. Bioquímica. 4ª ed. Madrid: Pearson.
• Müller-Esterl, W., 2008. Bioquímica fundamentos para medicina y ciencias de la vida. Barcelona: Reverté.
• Rodwell, V.W., Bender, D.A., Botham, K.M., Kennelly, P.J. y Weil, P.A., 2018. Harper Bioquímica ilustrada. [en liña] 31ª ed. México: McGraw-Hill/Interamericana. Dispoñible en: https://accessmedicina-mhmedical-com.ezbusc.usc.gal/Book.aspx?bookid=27…
• Nelson, D.L. & Cox, M.M., 2018. Lehninger Principios de Bioquímica. 7ª ed. Barcelona: Omega.
• Voet, D., Voet, J. & Pratt, C., 2016. Fundamentos de bioquímica: la vida a nivel molecular. 4ª ed. Buenos Aires: Ed. Médica Panamericana.
• McKee, T., y McKee, J.R., 2014. Bioquímica. Las bases moleculares de la vida.[en liña] 5ª ed. México: McGraw-Hill/Interamericana. Access in: https://accessmedicina-mhmedical-com.ezbusc.usc.gal/Book.aspx?bookid=19…
Complementary
- Koolman, J. e Röhm, K-H., 2012.. Color Atlas of Biochemistry. New York: Thieme Publishing Group.
- Roca, P., Oliver, J. e Rodríguez, A.M., 2003. Bioquímica. Técnicas y Métodos. Madrid: Hélice.
- Alberts, B., et al. (2016). Biología molecular de la célula. 6ª ed. Barcelona: Omega
- Lodish, H., et al. (2016). Biología celular y molecular. 7ª ed. Buenos Aires: Editorial Médica Panamericana.
- Paniagua, R. et al. (2017). Biología celular y molecular. 4ª ed. Madrid: McGraw-Hill Interamericana. Access in: https://accessmedicina-mhmedical-com.ezbusc.usc.gal/Book.aspx?bookid=22…
- Karp, G. (2014). Biología celular y molecular. Conceptos y experimentos. 7 ª ed. México: McGraw-Hill Interamericana. Access in: https://accessmedicina-mhmedical-com.ezbusc.usc.gal/Book.aspx?bookid=28…
Other resources
- http://biomodel.uah.es. Sitio web Universidad Alcalá de Henares
- http://www.ncbi.nlm.nih.gov/guide/ (The National Center for Biotechnology Information, (NCBI).
- BUSC Electronic resources: Cell, Nature, Science, Sciencedirect, etc.
- http://www.sebbm.es/BioROM/indices/index.html (web page Sociedade Española de Bioquímica e Bioloxía Molecular, and its didactic resources).
Basic / General
Consult the table of skills designed in the Memory of the Grade in Biology (2ª ed).
Transversal
CT1 - Ability to search, process, analyze and synthesize information from various sources.
CT2 - Capacity for reasoning, argumentation and critical thinking.
CT3 - Ability to work in groups and cover problem situations collectively.
CT8 - Ability to solve problems through the integrated application of their knowledge, promoting initiative and creativity.
CT9 - Ability to organize and plan work.
CT10 - Ability to interpret experimental results.
Specific
CE1 - Know and understand the physicochemical principles of biology.
CE3 - Know and be able to apply instrumental techniques and design work protocols in the laboratory and in the field, applying the appropriate regulations and techniques related to safety, hygiene, waste management and quality.
CE4 - Know the origin of life, the mechanisms of inheritance and its evolution.
CE7 - Know the structure of biomolecules, their physicochemical properties and relate them to their functions, integrating the different levels of organization of living beings.
CE8 - Understand the principles of bioenergy and biosignaling, and know the main metabolic pathways and their regulation, as well as the flow of genetic and biochemical information in living beings.
CE11 - Understand and integrate the functioning and regulation of the main physiological processes of living beings, as well as their interaction with the biotic and abiotic environment.
The course is designed to improve the Active Learning of students. The expository classes are conceived as general introductions to each topic, which will be complemented with the rest of the proposed activities. These activities are the individual study, the realization of practical activities in the laboratory and a practical notebook, the resolution of questions in seminars (PBL) and the resolution of doubts of the matter in tutorials.
Attendance at all activities is MANDATORY according to the Title Memory, except for students with official dispensation, but it will not be a REQUIREMENT to pass the subject, except those indicated below.
The individual study will be carried out with organized and detailed information provided by the teachers. The basis of this information will be the recommended basic bibliography, which will be supplemented with additional information.
In the magister classes, the teacher will explain the concepts of the subject with the support of audio-visual and computer media. It can have different formats (theory, problems and / or general examples, general guidelines for the topic), promoting student participation.
There will be 5 seminars of 2 hours each with the aim of carrying out, in small work groups, practical questions (problems, reasoning questions, PBL, etc.) related to the subjects of the subject, which will serve to deepen your knowledge. In these seminars you can bring notes, books and all the teaching materials you need. Attendance and the conduct of seminars will be voluntary, the response bulletins will be evaluated. At the end of each seminar, individual questionnaires will be held evaluable in electronic format by connection to the virtual campus, and their content will be examined.
Laboratory practices are practical classes in which the theoretical contents are applied, through the observation and management of biological material, instruments, etc., following the protocols prepared for this purpose. The teacher can count on the support of audio-visual and computer media. Laboratory practices are organized in 5 compulsory sessions (except for repeaters) of 2.5 or 3.5 hours. Students must carry out a series of experimental tests, collect the results obtained, review the content presented by the teachers and analyse everything appropriately to answer the questions and exercises formulated in the practice notebook, to prepare an individual practice report for their mandatory contribution. that will be evaluated.
All magister and interactive classes, as well as tutoring, will be face-to-face and will be held in the classroom following the official calendar and the calendar of the subject, provided that its organization is compatible with the adoption of the established measures and the Protocols for protection of the health of the University of Santiago de Compostela.
The tutorial will be in person following the calendar and the groups established by the Office of the Dean of the Faculty, or, at the request of the students, can be in person or by electronic mechanisms in agreement with the students (Virtual Campus, email or MS-Teams).
It is expressly forbidden for students to distribute the teaching material (both written and audiovisual) available on the Virtual Campus to people outside the course.
Plagiarism and misuse of technologies in performing tasks or tests:
In the event of fraudulent completion of exercises or tests, the provisions of the Regulations will be applied for the evaluation of the academic performance of the students and the revision of the grades.
1. General criteria: Non-assessable mandatory activities, Assessable mandatory activities, Assessable non-mandatory activities, Presentation criteria and Exceptions for repeaters.
Attendance at all activities is MANDATORY according to the subject sheet, except for students with official dispensation, but it will not be a REQUIREMENT to pass the subject, except for the FINAL TEST and the CONTINUOUS EVALUATION 1 (Workbook / Laboratory data and elaboration of the answers.
As exception for repeaters, they must repeat the entire evaluation, except for the CONTINUOUS EVALUATION 1 (Practice notebook / Laboratory data and preparation of the answers), and the CONTINUOUS EVALUATION 3 (Seminars / Autonomous and face-to-face work), if they have obtained at least the 50% of the grade. This score will be saved for two courses.
2. Specific evaluation criteria.
Tool: FINAL TEST
Completion / Criteria: The compulsory face-to-face final exam will represent 65% of the final grade. The subject evaluated in the exam includes the content of the expository classes and seminars. In the second call, only the compulsory final exam will be repeated (which will also represent 65% of the final grade), keeping the grade obtained in the continuous evaluation. The exam will have a test part and a short questions section that will cover all aspects related to the content of the subject. To pass, you must score on all short exam questions.
To add to the continuous assessment, you must score on all exam questions and earn a minimum (4/10 points). To pass the course, the final sum must be at least 5/10 points in total.
Weight: 30% questionary, 70% short questions.
Competences evaluated: CB 1-5 CG 1,4 CE 1,4,7,8,11 CT 1,2,8-10
Tool: CONTINUOUS ASSESSMENT 1
Completion / Criteria: Workbook / Laboratory data and preparation of the answers.
Weight: up to 15%.
It will only be added to the final grade if the specified score has been obtained for the exam.
Competences assessed: CB 1-5 CG 1,4 CE 1,3,4,7,8,11 CT 1,2,8-10
Tool: CONTINUOUS ASSESSMENT 2
Completion / Criteria: Use of classes. Activities / questionnaires proposed by classmates or teachers.
Weight: up to 5%.
It will only be added to the final grade if the specified score has been obtained for the exam.
Competences assessed: CB 1-5 CG 1-5 CE 2,3,4 CT 1,2,4-6
Tool: CONTINUOUS ASSESSMENT 3
Completion / Criteria: Seminars / Autonomous and face-to-face work, evaluated by peers and teachers.
Weight: up to 15%.
It will only be added to the final grade if the specified score has been obtained for the exam.
Competences evaluated: CB 1-5 CG 1,4 CE 1,4,7,8,11 CT 1,2,8-10
Contributions to continuous assessment will be made electronically in all settings.
TRAINING ACTIVITY MANDATORY HOURS (%)
Attendance hours 57 hours
Expository 30 100
Interactive seminar classes 10 100
Interactive laboratory classes 14 100
Tutorials 1 100
Review and review 2 100
Non-attendance hours 93 hours
Dedicated to individual study for the preparation of the subject and seminars for the preparation of practice reports during the course, and to prepare for the exam.
Total workload: 57 hours of face-to-face classes and 93 hours of personal work = 150 total hours (25 hours / ECTS x 6 ECTS = 150h).
- Attendance and active participation in class. Although attending and conducting the seminars are not mandatory, it is strongly recommended since: i) a large part of the exhibition material is reviewed; ii) is also subject to assessment; iii) questionnaires are evaluated (a significant percentage of the final grade); iv) the type of problems and questions addressed are very similar to some that will appear on the exam. It is also important to address problems and questions that you don't have time to ask in each seminar session and that will be available to students.
- For each hour of class two hours of study, using bibliographic material to understand and deepen the information obtained in class (it is essential that study time is as close as possible to class time).
- Study and weekly review of the taught subject and/or preparation of the proposed seminars before their presentation in class.
- Clarification with the teacher of possible doubts.
- Review of the final exam.
- Interest and attention in the new advances of this discipline that spread through the mass media, necessary to deep thinking.
Previous knowledge from the Biology and Chemistry courses in high school is supposed. If it is not the case, the student should learn it on its own.
Contributions to the Continuous Assessment will be made electronically, through the Virtual Campus or the institutional email.
Direct communication channels with students, in addition to the Subject’s operational Virtual Campus and the institutional email available, will be tutorials, forums or virtual sessions through MS Teams.
Oscar Javier Cordero Santamaria
Coordinador/a- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- Phone
- 881816935
- oscarj.cordero [at] usc.es
- Category
- Professor: University Professor
Manuel Rey Mendez
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- Phone
- 881816929
- manuel.rey.mendez [at] usc.es
- Category
- Professor: University Professor
Ma Del Pilar Arias Crespo
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- Phone
- 881816933
- pilar.arias [at] usc.es
- Category
- Professor: University Lecturer
| Monday | |||
|---|---|---|---|
| 10:00-11:00 | Grupo /TI-ECTS01 | Spanish | Virtual classroom |
| 11:00-12:00 | Grupo /TI-ECTS02 | Spanish | Virtual classroom |
| 12:00-13:00 | Grupo /TI-ECTS03 | Spanish | Virtual classroom |
| 13:00-14:00 | Grupo /TI-ECTS04 | Spanish | Virtual classroom |
| 16:00-17:00 | Grupo /CLE_02 | Spanish | Classroom 04: James Watson and Francis Crick |
| 17:00-18:00 | Grupo /CLE_01 | Spanish | Classroom 03. Carl Linnaeus |
| Tuesday | |||
| 10:00-11:00 | Grupo /TI-ECTS05 | Spanish | Virtual classroom |
| 11:00-12:00 | Grupo /TI-ECTS06 | Spanish | Virtual classroom |
| 12:00-13:00 | Grupo /TI-ECTS07 | Spanish | Virtual classroom |
| 13:00-14:00 | Grupo /TI-ECTS08 | Spanish | Virtual classroom |
| 16:00-17:00 | Grupo /CLE_02 | Spanish | Classroom 04: James Watson and Francis Crick |
| 17:00-18:00 | Grupo /CLE_01 | Spanish | Classroom 03. Carl Linnaeus |
| Wednesday | |||
| 10:00-11:00 | Grupo /TI-ECTS09 | Spanish | Virtual classroom |
| 11:00-12:00 | Grupo /TI-ECTS10 | Spanish | Virtual classroom |
| 12:00-13:00 | Grupo /TI-ECTS11 | Spanish | Virtual classroom |
| 13:00-14:00 | Grupo /TI-ECTS12 | Spanish | Virtual classroom |
| 16:00-17:00 | Grupo /CLE_02 | Spanish | Classroom 04: James Watson and Francis Crick |
| 17:00-18:00 | Grupo /CLE_01 | Spanish | Classroom 03. Carl Linnaeus |
| Thursday | |||
| 11:00-12:00 | Grupo /TI-ECTS13 | Spanish | Virtual classroom |
| 12:00-13:00 | Grupo /TI-ECTS14 | Spanish | Virtual classroom |
| 05.26.2023 16:00-20:00 | Grupo /CLE_01 | Classroom 01. Charles Darwin |
| 05.26.2023 16:00-20:00 | Grupo /CLE_02 | Classroom 01. Charles Darwin |
| 05.26.2023 16:00-20:00 | Grupo /CLE_01 | Classroom 02. Gregor Mendel |
| 05.26.2023 16:00-20:00 | Grupo /CLE_02 | Classroom 02. Gregor Mendel |
| 05.26.2023 16:00-20:00 | Grupo /CLE_02 | Classroom 03. Carl Linnaeus |
| 05.26.2023 16:00-20:00 | Grupo /CLE_01 | Classroom 03. Carl Linnaeus |
| 07.05.2023 16:00-20:00 | Grupo /CLE_01 | Classroom 01. Charles Darwin |
| 07.05.2023 16:00-20:00 | Grupo /CLE_02 | Classroom 01. Charles Darwin |
| 07.05.2023 16:00-20:00 | Grupo /CLE_01 | Classroom 02. Gregor Mendel |
| 07.05.2023 16:00-20:00 | Grupo /CLE_02 | Classroom 02. Gregor Mendel |