ECTS credits ECTS credits: 6
ECTS Hours Rules/Memories Student's work ECTS: 99 Hours of tutorials: 3 Expository Class: 24 Interactive Classroom: 24 Total: 150
Use languages Spanish, Galician
Type: Ordinary Degree Subject RD 1393/2007 - 822/2021
Departments: Biochemistry and Molecular Biology
Areas: Biochemistry and Molecular Biology
Center Faculty of Biology
Call: First Semester
Teaching: Sin docencia (Extinguida)
Enrolment: No Matriculable
To
- Learn to identify and distinguish the structure, properties and function of biomolecules.
- Learn to carry out processes of purification and analysis of biomolecules.
- Identify the relationship between the structure and function of biomolecules.
- Distinguish the different classes of enzymes and their catalysis mechanisms, as well as the principles of enzymatic regulation.
- Learn to measure enzymatic activities.
- Apply the principles of thermodynamics to biological systems.
- List the mechanisms and elements of cell signalling.
All the different activities will be face-to-face.
MAGISTER CLASSES (27 hours)
• Lesson 1. Biochemical science. Molecular design of life (2h).
• Lesson 2. Carbohydrates. General characteristics and biological function (2h).
• Lesson 3. Lipids. General characteristics and biological function (2h).
• Lesson 4. Nucleotides and amino acids (2h).
• Lesson 5. Peptide bond and proteins. Three-dimensional structure and functionality of proteins (2h).
• Lesson 6. Function of proteins. Myoglobin and hemoglobin (2h).
• Lesson 7. Biological membranes. Structure and properties. Mechanisms of transport through the membrane (2h).
• Lesson 8. Bioenergetics: study of energy transformations and exchanges (2h).
• Lesson 9. Enzymes: structure and function (2h).
• Lesson 10. Enzymatic reaction. Kinetics of the enzymatic reaction (3h).
• Lesson 11. Inhibition and regulation of the enzymatic reaction (3h).
• Lesson 12. Cell signaling and its mechanisms (2h).
• Lesson 13. Introduction to metabolism and its regulation (1h).
INTERACTIVE CLASSES / SEMINARS PROGRAM (6 hours)
Resolution, in small work groups or individually, to be carried out in the classroom, of practical questions (problems, reasoning questions, etc.) related to the topics of the expository material, which serve to deepen their knowledge, with the following topics:
• Seminar 1: carbohydrates (1h)
• Seminar 2: lipids (1h)
• Seminar 3: amino acids and proteins (1h)
• Seminar 4: biological membranes and bioenergetics (1h)
• Seminar 5: enzymatic activity (1h)
• Seminar 6: enzyme inhibition (1h)
LABORATORY PROGRAM (PRESENTIAL) (15 hours)
To be carried out in the laboratory.
• PRACTICE 1. Obtaining extracts from animal tissue (calf liver) and fractionation of cellular organelles. Preparation of reagents (3 h).
• PRACTICE 2. Obtaining and analysis of DNA from eukaryotic cell nuclei. Electrophoretic analysis on agarose gels (3 h).
• PRACTICE 3. Quantitative determination of proteins. Lowry's method (3 h).
• PRACTICE 4. Isolation and quantification of hepatic glycogen (3 h).
• PRACTICE 5. Enzymology: kinetics and enzyme inhibition (3 h).
TUTORING PROGRAM (3 hours)
The first hour is placed at the beginning of the course to explain the development of the Course and the Assessment System. The other two will be used to answer common doubts on the development of the Course and its contents, and its call can be online.
BASIC
• Berg, J.M., Tymoczko, J.L. y Stryer L., 2015. Bioquímica con aplicaciones clínicas. 7ª ed. Barcelona: Reverté.
• *Rodwell, V.W., Bender, D.A., Botham, K.M., Kennelly, P.J. y Weil, P.A., 2018. Harper Bioquímica ilustrada. [en línea] 31ª ed. México: McGraw-Hill/Interamericana. Disponible en: https://accessmedicina-mhmedical-com.ezbusc.usc.gal/Book.aspx?bookid=27…
• Nelson, D.L. y Cox, M.M., 2018. Lehninger Principios de Bioquímica. 7ª ed. Barcelona: Omega.
• Voet, D., Voet, J.G.y Pratt, C.W., 2016. Fundamentos de bioquímica: la vida a nivel molecular. 4ª ed. Buenos Aires: Ed. Médica Panamericana.
• *McKee, T., y McKee, J.R., 2014. Bioquímica. Las bases moleculares de la vida.[en línea] 5ª ed. México: McGraw-Hill/Interamericana. Disponible en: https://accessmedicina-mhmedical-com.ezbusc.usc.gal/Book.aspx?bookid=19…
COMPLEMENTARY
• *Sánchez Enríquez, S., Flores Alvarado, L.J., Gurrola Díaz, C.M., Heredia Chávez. P., 2014, Manual de prácticas de laboratorio de bioquímica. [en línea] 3ª ed. México: McGraw-Hill/Interamericana. Disponible en: https://accessmedicina-mhmedical-com.ezbusc.usc.gal/Book.aspx?bookid=14…
• Roca, P., Oliver, J. y Rodríguez, A.M., 2003. Bioquímica. Técnicas y Métodos. Madrid: Hélice.
ANOTHER RESOURCES
- http://biomodel.uah.es. Sitio web Universidad Alcalá de Henares
-http://www.sebbm.es/BioROM/indices/index.html
-http://www.pubmed.com (books)
-Recursos electrónicos de la BUSC: Cell, Nature, Science, Sciencedirect, etc.
Basic / General
Those that appear reflected in the Report of the Degree of Biotechnology.
Transversal
CT1 - Think in an integrated way and approach problems from different perspectives.
CT2 - Search, process, analyze and synthesize information from various sources.
CT4 - Interpret experimental results and identify consistent and inconsistent elements.
CT5 - Work as a team.
CT6 - Reason critically.
Specific
CE2- Understand and know how to apply the physical-chemical principles of biological processes with application in Biotechnology, as well as the main tools used to investigate them.
CE3- Know and know how to apply the instrumental techniques and work protocols in a laboratory, applying the regulations and techniques related to safety and hygiene, waste management and quality.
CE4- Have an integrated vision of the functioning of cells, including their biomolecules, metabolism, gene expression, relationship between cell compartments, as well as communication mechanisms and cell signaling.
The course is designed to improve the Active Learning of students. The expository classes are conceived as general introductions to each topic, which will be complemented with the rest of the proposed activities. These activities are the individual study, the realization of practical activities in the laboratory and a practical notebook, the resolution of questions in seminars (PBL) and the resolution of doubts of the matter in tutorials.
Attendance at all activities is MANDATORY according to the Title Memory, except for students with official dispensation, but it will not be a REQUIREMENT to pass the subject, except those indicated below.
The individual study will be carried out with organized and detailed information provided by the teachers. The basis of this information will be the recommended basic bibliography, which will be supplemented with additional information.
In the magister classes, the teacher will explain the concepts of the subject with the support of audio-visual and computer media. It can have different formats (theory, problems and / or general examples, general guidelines for the topic), promoting student participation.
There will be 6 seminars of 1 hour each with the aim of carrying out, in small work groups, practical questions (problems, reasoning questions, PBL, etc.) related to the subjects of the subject, which will serve to deepen your knowledge. In these seminars you can bring notes, books and all the teaching materials you need. Attendance and the conduct of seminars will be voluntary, the response bulletins will be evaluated. At the end of each seminar, individual questionnaires will be held evaluable in electronic format by connection to the virtual campus, and their content will be examined.
Laboratory practices are practical classes in which the theoretical contents are applied, through the observation and management of biological material, instruments, etc., following the protocols prepared for this purpose. The teacher can count on the support of audio-visual and computer media. Laboratory practices are organized in 5 compulsory sessions (except for repeaters) of 2.5 or 3.5 hours. Students must carry out a series of experimental tests, collect the results obtained, review the content presented by the teachers and analyse everything appropriately to answer the questions and exercises formulated in the practice notebook, to prepare an individual practice report for their mandatory contribution. that will be evaluated.
All magister and interactive classes, as well as tutoring, will be face-to-face and will be held in the classroom following the official calendar and the calendar of the subject, provided that its organization is compatible with the adoption of the established measures and the Protocols for protection of the health of the University of Santiago de Compostela.
The tutorial will be in person following the calendar and the groups established by the Office of the Dean of the Faculty, or, at the request of the students, can be in person or by electronic mechanisms in agreement with the students (Virtual Campus, email or MS-Teams).
It is expressly forbidden for students to distribute the teaching material (both written and audiovisual) available on the Virtual Campus to people outside the course.
Plagiarism and misuse of technologies in performing tasks or tests:
In the event of fraudulent completion of exercises or tests, the provisions of the Regulations will be applied for the evaluation of the academic performance of the students and the revision of the grades.
1. General criteria: Non-assessable mandatory activities, Assessable mandatory activities, Assessable non-mandatory activities, Presentation criteria and Exceptions for repeaters.
Attendance at all activities is MANDATORY according to the Title Memory, except for students with official dispensation, but it will not be a REQUIREMENT to pass the subject, except for the FINAL TEST and the CONTINUOUS EVALUATION 1 (Workbook / Laboratory data and elaboration of the answers).
As exception for repeaters, they must repeat the entire evaluation, except for the CONTINUOUS EVALUATION 1 (Practice notebook / Laboratory data and preparation of the answers), and the CONTINUOUS EVALUATION 3 (Seminars / Autonomous and face-to-face work), if they have obtained at least the 50% of the grade. This score will be saved for two courses.
2. Specific evaluation criteria.
Tool: FINAL TEST
Completion / Criteria: The compulsory face-to-face final exam will represent 65% of the final grade. The subject evaluated in the exam includes the content of the expository classes and seminars. In the second call, only the compulsory final exam will be repeated (which will also represent 65% of the final grade), keeping the grade obtained in the continuous evaluation. The exam will have a test part and a short questions section that will cover all aspects related to the content of the subject. To pass, you must score on all short exam questions.
To add to the continuous assessment, you must score on all exam questions and earn a minimum (4/10 points). To pass the course, the final sum must be at least 5/10 points in total.
Weight: 30% questionary and 70% short questions.
Competences evaluated: CB 1-5; CG 1; CE 2-4; CT 1,2,4,6.
Tool: CONTINUOUS ASSESSMENT 1
Completion / Criteria: Workbook / Laboratory data and preparation of the answers.
Weight: up to 15%.
It will only be added to the final grade if the specified score has been obtained for the exam.
Competences assessed: CB 1-5; CG 1-4; CE 2-4; CT 1,2,4,6.
Tool: CONTINUOUS ASSESSMENT 2
Completion / Criteria: Use of classes. Activities / questionnaires proposed by classmates or teachers.
Weight: up to 5%.
It will only be added to the final grade if the specified score has been obtained for the exam.
Competences assessed: CB 1-5; CG 1; CE 2-4; CT 1,2,4-6
Tool: CONTINUOUS ASSESSMENT 3
Completion / Criteria: Seminars / Autonomous and face-to-face work, evaluated by peers and teachers.
Weight: up to 15%.
It will only be added to the final grade if the specified score has been obtained for the exam.
Competences evaluated: CB 1-5; CG 1; CE 2-4; CT 1,2,4-6
Contributions to continuous assessment will be made electronically in all settings.
Presential hours: 53 hours
27 hours of exposition
15 practical laboratory hours
6 hours of seminars
3 hours of tutoring
2 hours of exam
Non-presential hours: 97 hours
87 hours of dedication to individual study, 10 hours to the elaboration of the memory of practices.
Total volume of work: 150 total hours (25 hours / ECTS x 6 ECTS = 150h).
- Attendance and active participation in class. Although attending and conducting the seminars are not mandatory, it is strongly recommended since: i) a large part of the exhibition material is reviewed; ii) is also subject to assessment; iii) questionnaires are evaluated (a significant percentage of the final grade); iv) the type of problems and questions addressed are very similar to some that will appear on the exam. It is also important to address problems and questions that you don't have time to ask in each seminar session and that will be available to students.
- For each hour of class two hours of study, using bibliographic material to understand and deepen the information obtained in class (it is essential that study time is as close as possible to class time).
- Study and weekly review of the taught subject and/or preparation of the proposed seminars before their presentation in class.
- Clarification with the teacher of possible doubts.
- Review of the final exam.
- Interest and attention in the new advances of this discipline that spread through the mass media, necessary to deep thinking.
Previous knowledge from the Biology and Chemistry courses in high school is supposed. If it is not the case, the student should learn it on its own.
Contributions to the Continuous Assessment will be made electronically, through the Virtual Campus or the institutional email.
Direct communication channels with students, in addition to the Subject’s operational Virtual Campus and the institutional email available, will be tutorials, forums or virtual sessions through MS Teams.
Oscar Javier Cordero Santamaria
Coordinador/a- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- Phone
- 881816935
- oscarj.cordero [at] usc.es
- Category
- Professor: University Professor
Manuel Rey Mendez
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- Phone
- 881816929
- manuel.rey.mendez [at] usc.es
- Category
- Professor: University Professor
Ester Polo Tobajas
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- ester.polo [at] usc.es
- Category
- Researcher: Ramón y Cajal
| Monday | |||
|---|---|---|---|
| 16:00-17:00 | Grupo /CLE_01 | Spanish | Classroom 08. Louis Pasteur |
| Wednesday | |||
| 16:00-17:00 | Grupo /CLE_01 | Spanish | Classroom 08. Louis Pasteur |
| 01.25.2023 16:00-20:00 | Grupo /CLE_01 | Classroom 04: James Watson and Francis Crick |
| 06.22.2023 16:00-20:00 | Grupo /CLE_01 | Classroom 03. Carl Linnaeus |