ECTS credits ECTS credits: 6
ECTS Hours Rules/Memories Student's work ECTS: 99 Hours of tutorials: 3 Expository Class: 24 Interactive Classroom: 24 Total: 150
Use languages Spanish, Galician, English
Type: Ordinary Degree Subject RD 1393/2007 - 822/2021
Departments: Organic Chemistry
Areas: Organic Chemistry
Center Faculty of Chemistry
Call: First Semester
Teaching: With teaching
Enrolment: Enrollable
It is expected that the student will know the properties and reactivity of the polyfunctional organic compounds, acquiring a balanced formation between theory and experimentation.
Theoretical contents.
Item 1. - Enols and enolates. Aldol condensation.
Acidity of aldehydes and ketones: enolate ions. Keto-enol tautomerism. Halogenation of aldehydes and ketones. Alkylation of aldehydes and ketones. Enamines. Aldol condensation. Crossed aldol condensation. Intramolecular aldol condensation.
Item 2. - Aldehydes and ketones alpha, beta-unsaturated.
Properties of alpha, beta-unsaturated aldehydes and ketones. Conjugate additions to alpha, beta-unsaturated aldehydes and ketones. 1,2 and 1,4 additions of organometallic compounds. Alpha, beta dialkylation. Enolate ion conjugate additions: Michael Addition and Robinson annulation.
Chapter 3. - Carboxylic acids and derivatives.
Naming the carboxylic acids. Structural and physical properties of the carboxylic acids. Acidic and basic character of the carboxylic acids. Carboxylic acids synthesis. Reduction of carboxylic acids. Halogenation alpha to the carboxyl group.
Chapter 4. - Derivatives of carboxylic acids.
Substitution at the carboxy carbon: the addition-elimination mechanism. Preparation of acyl halides and acid anhydrides. Chemistry of esters: Esterification and hydrolysis. Lactones. Preparation of amides, imides and lactams. Relative reactivities of the carboxylic derivatives. Reactions of acyl halides. Reactions of acid anhydrides. Reactions of esters. Reactions amides . Nitriles.
Item 5. - Amines and derivatives.
Naming the amines. Structural and physical properties. Acidity and basicity of the amines. Amine synthesis methods. Quaternary ammonium salts: Hofmann elimination. Mannich reaction: Alkylation of enols by iminium salts. Nitrosation of amines: N-nitrosamines and diazonium salts. Nitrosation of amides: N-Nitrosoamides. Diazo compounds: Synthetic methods and reactions.
Item 6. - Ester enolates. Enolates of beta-dicarbonyl compounds.
Beta-dicarbonyl compounds: Claisen condensations. Beta-dicarbonyl compounds as synthetic intermediates: Acetoacetic synthesis and malonic synthesis. Chemistry of the beta-dicarbonyl anions: Michael additions. Synthetic equivalents of acyl anions: cyclic thioacetals and adducts thiazolium salt/aldehyde in the preparation of alpha-hydroxy ketones.
Item 7. - Heterocyclic compounds.
Naming the heterocycles. Non-aromatic heterocycles. Aromatic Heterociclopentadienes: Structure and properties. Reactions of aromatic heterociclopentadienes. Structure and synthesis of pyridine: An azabenzene. Reactions of pyridine. Quinoline and isoquinoline: The benzopiridinas.
Practical contents:
Practice 1. - Beckman Transposition: synthesis of acetanilide.
Practice 2. - Aldol condensation: Synthesis of dibenzalacetone.
Practice 3.- Acetoacetic Synthesis: Preparation of 3-methyl-2-cyclohexen-1-one
Bibliography (Reference Manual).
K. P. C. Vollhartd, N. E. Schore; "Organic Chemistry: Structure and Function", 6th Ed., W. H. Freeman and Company, New York 2011.
Further reading (book of practice).
M. A. Martínez Grau, A. G. Csákÿ; "Técnicas experimentales en Síntesis Orgánica", 1st Ed., Editorial Synthesis, 2001.
CORE COMPETENCES
CB1 - The students must possess and understand knowledge in the area of study based on the general secondary education, that uses to find a level that, although gets support in advanced textbooks, includes also some aspect implying knowledge from the forefront in its area of study.
CG1 - Graduates must possess and understand the most important concepts, methods and results in the different branches of Chemistry, with a historical perspective in its development.
CG2 - The students must be able to collect and interpret relevant data, information and results; to reach conclusions and issue reasoned reports about scientific and technological problems, and problems in other spheres that demand the use of knowledge in Chemistry.
CG3 - The students must be able to apply the acquired theoretical and practical knowledge and also the capacity of analysis and abstraction in the definition and planing of problemas, and in the search of solutions in academic and profesional contexts.
CG4 - The students must be able to communicate, in a written or oral manner, knowledge, procedures, results and ideas in Chemistry, both to specialists and non specialists.
CG5 - The students must be able to learn new knowledge and techniques in any scientific or technological discipline, autonomously and organizing time and resources.
SPECIFIC SKILLS
EC7 - Know properties of organic, inorganic and organometallic compounds.
CE13 - Be able to demonstrate knowledge and understanding of essential facts, concepts, principles and theories related to the areas of chemistry.
CE14 - Be able to solve qualitative and quantitative problems according to previously developed models.
CE18 - Be able to perform laboratory procedures involved in standards analytical and synthetic work in conjunction with organic and inorganic systems.
CE22 - Understand the relationship between theory and experiment.
GENERIC COMPETENCES
CT1 - Acquire capacity for analysis and synthesis.
CT2 - Develop capacity for organization and planning.
CT3 - To acquire knowledge of a foreign language.
CT4 - Be able to solve problems.
CT5 - Be able to make decisions.
a) Presential teaching activities:
Will consist of lectures, small group interactive classes (seminars and classes of problems), interactive classes and practical laboratory classes very small group interactive (tutorials).
b) Non-presential teaching activities.
Personal work dedicated to the preparation of the material.
c) Virtual Classroom.
Through which provide all the material relating to the matter: Teaching Guide, summaries of lessons, problem sets, ads, etc..
According to the document "Guidelines for the development of safe face-to-face teaching, academic year 2020-2021", two new possible scenarios are envisined for the teaching methodology just in case that the indicated scenario of adapted normality can not be carried out. The new scenarios are included in the comment section under the title of the Contingency Plan.
Learning evaluation system.
The assessment of this will be done through continuous assessment and the completion of a final exam.
The laboratory practices are mandatory and absences must be justified and documented and recovered according to the professor.
Continuous assessment (N1) will weigh 30% in the grade for the course and will consist of three components: small group interactive classes (seminars, 40%), interactive classes in very small groups (tutoring, 10%) and practical laboratory (50%). Seminars and tutorials will include exercises and exercises work in person and delivered to the teacher.
The evaluation of the seminars and tutorials will take into account the active participation of students in the interactive classes and the set of exercises performed and delivered in person to the teacher. For the evaluation of laboratory practices items to evaluate are: pre-test, organization and neatness in the laboratory, practice execution and results.
The final exam will cover all the contents of the course and will include issues of laboratory practices, which contribute 15% to the overall mark of the test (N2).
The student's score, which shall not be less than the final exam, will be obtained as a result of applying the following formula:
Score = maximum Note (0.3 x N1 + 0.7 x N2, N2)
N1 is the corresponding to the continuous assessment (scale 0-10) and N2 numerical final exam (0-10 scale) numerical grade.
In any case, to pass the course, it will be an essential requirement be qualified as suitable in the labs.
The repeaters have the same system of class attendance than those who study the subject for the first time, with the following exception:
• The repeater students of this theoretical and practical course, who have passed the laboratory practices in a previous edition, will retain the mark obtained in this section for up to two academic years. Therefore, they will not repeat the practical work at the lab, but must attend lectures and interactive sessions on an equal footing with new students.
Throughout the course the following competencies will be evaluated:
Seminars. CG1, CG2, CG3, CG4, CG5; CE14; CT1, CT3 y CT4
Laboratory Practices: CG2, CG3; CE7, CE18, CE22; CT2, CT5
Tutorials: CG4; CE13, CE14; CT4
Final Exam: CG1, CG2, CG3, Cg4, CG5; CE7, CE13, CE14; CT1, CT2, CT4.
In cases of fraudulent performance of exercises or tests, the provisions of the regulations for evaluating student academic performance and reviewing qualifications will apply.
According to the document "Guidelines for the development of safe face-to-face teaching, academic year 2020-2021", two new possible scenarios are envisioned for the assessment system just in case that the indicated scenario of adapted normality can not be carried out. The new scenarios are included in the comment section under the title of the Contingency Plan.
Work in the classroom.
Lectures in large groups: 23
Interactive classes in small groups (seminars): 8
Laboratory: 20
Interactive classes in very small group (tutorials): 2
Total working hours in the classroom or lab: 53 hours.
Personal work:
Individual study or in group: 46 hours.
Solving exercises and other work: 31 hours
Preparation of oral, written, preparation of exercises, library or similar activity: 10 hours
Preparation of laboratory work and development of the practice report: 12 hours.
Total personal work: 99 hours
It is highly recommended to assist to the lectures.
It is very important to keep the study of matter "up" to reinforce what they have studied in class exercises (self-model).
Learn and understand concepts and mechanisms.
Perform exercises to acquire ease and agility in handling concepts and theoretical resources.
CONTINGENCY PLAN
Scenery 1: adapted normality (no restrictions to physical attendance).
Lectures and interactive lessons will be given under physical attendance modality. Exceptionally, on-line attendance will be implemented up to a 10% of the subject hours. For laboratory classes, this maximum limit might reach 25%.
Tutorships might be partially given on-line.
Final exams will be under physical attendance modality.
Scenery 2: social distancing (partial restrictions to physical attendance).
Lectures might be given totally on-line (when social distancing not possible at classroom) or combined with 50% physical attendance when social distancing is possible. As for interactive lessons (seminars and laboratories), physical and on-line attendance might combine up to a 50% on-line, if required.
Tutorships will preferentially be on-line.
Final exams will preferentially be on-line.
Scenery 3: closed facilities (no physical attendance).
All classes will be on-line, either under synchronous or asynchronous formats.
Tutorships will exclusively be on-line.
Final exams will exclusively be on-line.
For the three sceneries, on-line classes will be given with MS Teams and Moodle.
In case of exercises or test realized by dishonest means, the "Evaluation rules of students’ academic performance and qualifications" will be of application.
Concepcion Gonzalez Bello
- Department
- Organic Chemistry
- Area
- Organic Chemistry
- Phone
- 881815726
- concepcion.gonzalez.bello [at] usc.es
- Category
- Professor: University Lecturer
Manuel Maria Paz Castañal
- Department
- Organic Chemistry
- Area
- Organic Chemistry
- Phone
- 881814218
- manuel.paz [at] usc.es
- Category
- Professor: University Lecturer
Ramon Jose Estevez Cabanas
- Department
- Organic Chemistry
- Area
- Organic Chemistry
- Phone
- 881815731
- ramon.estevez [at] usc.es
- Category
- Professor: University Professor
Carlos Eugenio Saa Rodriguez
Coordinador/a- Department
- Organic Chemistry
- Area
- Organic Chemistry
- Phone
- 881814400
- carlos.saa [at] usc.es
- Category
- Professor: University Professor
Alfonso Bayón Fernández
- Department
- Organic Chemistry
- Area
- Organic Chemistry
- alfonso.bayon [at] usc.es
- Category
- Xunta Pre-doctoral Contract
Ana Alcalde Ordóñez
- Department
- Organic Chemistry
- Area
- Organic Chemistry
- ana.alcalde.ordonez [at] rai.usc.es
- Category
- Ministry Pre-doctoral Contract
María Victoria López Corbalán
- Department
- Organic Chemistry
- Area
- Organic Chemistry
- mariavictoria.lopez [at] usc.es
- Category
- Xunta Pre-doctoral Contract
| Tuesday | |||
|---|---|---|---|
| 11:00-12:00 | Grupo /CLE_02 | Spanish | Analytical Chemistry Classroom (2nd floor) |
| Wednesday | |||
| 10:00-11:00 | Grupo /CLE_01 | Spanish | Organic Chemistry Classroom (1st floor) |
| Thursday | |||
| 09:00-10:00 | Grupo /CLIS_04 | Spanish | Mathematics Classroom (3rd floor) |
| 10:00-11:00 | Grupo /CLIS_02 | Spanish | Physics Classroom (3rd floor) |
| 11:00-12:00 | Grupo /CLIS_03 | Spanish | Analytical Chemistry Classroom (2nd floor) |
| 13:00-14:00 | Grupo /CLIS_01 | Spanish | Organic Chemistry Classroom (1st floor) |
| Friday | |||
| 09:00-10:00 | Grupo /CLE_02 | Spanish | Analytical Chemistry Classroom (2nd floor) |
| 13:00-14:00 | Grupo /CLE_01 | Spanish | Organic Chemistry Classroom (1st floor) |
| 01.26.2021 16:00-20:00 | Grupo /CLE_01 | Biology Classroom (3rd floor) |
| 01.26.2021 16:00-20:00 | Grupo /CLE_01 | General Chemistry Classroom (2nd floor) |
| 01.26.2021 16:00-20:00 | Grupo /CLE_01 | Inorganic Chemistry Classroom (1st floor) |
| 01.26.2021 16:00-20:00 | Grupo /CLE_01 | Physical Chemistry Classroom (ground floor) |
| 07.09.2021 16:00-20:00 | Grupo /CLE_01 | Biology Classroom (3rd floor) |
| 07.09.2021 16:00-20:00 | Grupo /CLE_01 | General Chemistry Classroom (2nd floor) |
| 07.09.2021 16:00-20:00 | Grupo /CLE_01 | Inorganic Chemistry Classroom (1st floor) |