
Wajih Al-Soufi
Biographical sketch
ResearchGate ORCID ResearcherID Google Scholar LinkedIn
- 1962 born in Hamburg, Germany.
- 1982-1987 Degree in Physical Sciences in the Carolo-Wilhelmina University in Braunschweig and Georg-August University in Göttingen, Germany.
- 1986-1988 Diploma Thesis in the Department of Spectroscopy of the Max-Planck Institute for Biophysical Chemistry in Göttingen (Dr. K.-H. Grellmann, Prof. Dr. A. Weller). 1988: “Diplom” in Physical Sciences in Göttingen.
- 1988-1991 Ph.D. Thesis in the Department of Spectroscopy of the Max-Planck Institute for Biophysical Chemistry in Göttingen. "Blitzlichtphotolytische Untersuchungen von Tunneleffekten bei Wasserstoff-Umlagerungen im Triplettzustand" ("Study of the tunnel effect during hydrogen transfer in the triplet state using flash photolysis") (Dr. K.-H. Grellmann, Prof. Dr. J. Troe). 1991 Ph.D. in Chemistry in Göttingen.
- 1992-1996 R&D Project Optical Sensors for Anesthesia, Drägerwerk AG, Medical Technology, (Lübeck, Germany).
- 1996-2001 Assistant Professor for Physical Chemistry, USC, Lugo, Spain.
- Since 2/7/2002 Associate Professor for Physical Chemistry, USC, Lugo, Spain.
- 2015 National Accreditation as Full Professor (Acreditación National para Catedrático de Universidad), 5th of may, 2015
- Since 2013 Founder and Technical Coordinator of the “Teaching Innovation Group XuvenCiencia” http://www.usc.es/xuvenciencia. “XuvenCiencia”, offers training to school staff, develops educational science kits and organizes one of the biggest annual scientific summer campus for young people in Spain.
- 2023 Full Professor of Physical Chemistry
Participation in I+D projects
"Kinetische Untersuchungen von lichtinduzierten Proton-Tunnelprozessen" (´Kinetic investigation of photoinduced proton tunnel processes´), DFG, SFB-93, Max-Planck Institute of Biophysical Chemistry, Göttingen, Germany. 1986 - 1991, (Dr. Karl-Heinz Grellmann )
"Synthesis of new materials derived from cyclodextrins and study of its applications", CYTED, Spain, Chile, Brazil, Cuba, Costa Rica, Colombia and Uruguay, 1996 - 2000, (PI: José Vázquez Tato).
"Synthesis of derivatives of cyclodextrins and study of their aplications. Autoassociation of steroidic surfactants. ", PGIDT (PXI), 1999 – 2001, (José Vázquez Tato).
"Polymeric supramolecular derivatives of cyclodextrins and bile salts", PGIDT, Xunta de Galicia, 2001 – 2004, (PI: José Vázquez Tato).
"Structural study of organized media using proton transfer probes", Ministry for Education and science, MEC, CTQ2004-07683-C02-02, 2004 - 2007, (PI: Wajih Al-Soufi).
"Red temática de ciencias y materiales moleculares"
Xunta de Galicia, PGIDIT05PXI20901RT, 2005-2006, PI: Enrique Guitian Rivera
"Red temática de ciencias y materiales moleculares"
Xunta de Galicia, Consellería de Educación e Ordenación Universitaria
2006/124, 2006 - 2008, PI: Enrique Guitian Rivera
"Ayudas para la consolidación y estructuración de unidades de investigación competitivas del sistema gallego de I+D+I",
Xunta de Galicia, Consellería de Innovación e Industria
INCITE07PXI209034ES, 2007
"Fluorescent probes for the study of chemical processes in solution and in supramolecular systems. Applications of technological and biomedical interest",
Ministerio de Educación y Ciencia, CTQ2007-68057-C02-02/BQU,
2007 - 2010, PI: Wajih Al-Soufi
"Dynamics of the transport of mater through biomimetic membranes studied with single molecule fluorescence techniques"
Consellería de Economía e Industria, Xunta de Galicia, Incite09 262 304 PR, 2009-2012, PI: Wajih Al-Soufi
"Single-Molecule Fluorescence Detection for structural and dynamic studies of supramolecular systems of biomedical and technological interest". Ministerio de Ciencia e Innovación - CTQ2010-21369, 2010-2012,PI: Wajih Al-Soufi
"Consolidación e estruturación de unidades de investigación competitivas - REDES."
Consellería de Cultura, Educación e Ordenación Universitaria (2012-PG208) CN2012/314
2012-2014, IP Guitián Rivera,Enrique
"Ayudas para la consolidación y estructuración de unidades de investigación competitivas del sistema universitario de Galicia" Xunta de Galicia, ref. GPC2013/052, 2013–2015.
"Binding of Small Molecules to DNA: Dynamics, Photophysics and Conformations studied by Single-Molecule and Time-Resolved Fluorescence Spectroscopy", Proyectos de I+D+i, del programa estatal de investigación, desarrollo e innovación orientada a los retos de la sociedad, CTQ2014-59020-R, 01/01/2015 - 31/12/2017, IPs Al-Soufi, Wajih; Mosquera, Manuel
Ph. D. theses
"Supramolecular structures generated by cyclodextrins". Emilio Álvarez Parrilla. USC, 2000
"Complexation of biocides by cyclodextrins". Minerva Lezcano Brito. USC, 2002
"Structural and dynamic study of organized systems using fluorescent probes". Belén Reija Otero. USC, 2007
“Single-Molecule Fluorescence studies of the dynamics in supramolecular systems of biological interest”, Jorge Bordello Malde, USC, 2013
"Study of the association of supramolecular systems by fluorescence techniques: from cyclodextrins to beta-amyloids", Sonia Freire, USC, 2015
"Structural and dynamic study of supramolecular association processes", Lucas Piñeiro, USC, 2015
Diploma theses
"Study of the photophysical behavior of the 2-toluidin-6-naphtalensulphonate and its inclusion complexes with beta-cyclodextrin". Ana Íñigo Espiga. USC, 1999
"Aggregation of poligalacturonic acid". Maria Freire Rodriguez. USC, 2000
"Advanced analysis of time resolved spectra". Belén Reija Otero. USC, 2003
Seminars
"Fluorescence spectroscopy. Applications to physical chemistry and biological systems." Central University of "Marta Abreu" of Las Villas, Santa Clara, Cuba, October of 1999.
"Principal component analysis and global analysis of series of fluorescence spectra.", Seminar by invitation of the Cooperative Research Center SFB663, Heinrich-Heine Universität, Düsseldorf, August 2005
"Single Molecule Fluorescence Spectroscopy", II Iberian Photochemistry Course (CIF-II, July 23-24, 2007, Faro, Portugal)
"Supramolecular dynamics studied by fluorescence correlation spectroscopy", WORKSHOP ON SINGLE MOLECULE FLUORESCENCE IMAGING", Coordinator, Bilbao, España, 24/09/2009
Publications
CRISPR/Cas9 Delivery Systems to Enhance Gene Editing Efficiency
Amyloid Capture and Aggregation Inhibition by Human Serum Albumin
International Journal of Biological Macromolecules, Volume 301, April 2025, 140367
https://doi.org/10.1016/j.ijbiomac.2025.140367
(Preprint: ChemRxiv, 2024, Version 1, 10.26434/chemrxiv-2024-fr8gt)
Thiazole Orange as fluorescent marker for the detection and quantification of dsDNA
ChemRxiv, 2024, Version 1, Preprint, 10.26434/chemrxiv-2024-lbxzx
Critical aggregation concentration and reversibility of amyloid-β (1–40) oligomers
Archives of Biochemistry and Biophysics, 2024, 761, 110179, DOI 10.1016/j.abb.2024.110179
Methods in Molecular Biology, 2023, 2551, 1–14. DOI: 10.1007/978-1-0716-2597-2_1
Frontiers in Chemistry 2022, 10, 1042658. DOI: 10.3389/fchem.2022.1042658 (Open Access)
International Journal of Molecular Sciences 2022, 23(2), 925. DOI: 10.3390/ijms23020925 (Open Access)
Molecules 2021, 26, no. 17: 5339. https://doi.org/10.3390/molecules26175339 (Open Access)
Journal of Chemical Education 2020, 97, 9, 3090–3096, https://doi.org/10.1021/acs.jchemed.0c00745
Scientific Reports 2019, 9, Article number: 12897, DOI: 10.1038/s41598-019-49210-0 (Open Access)
Scientific Reports 2018, 8, Article number: 1783, DOI: 10.1038/s41598-018-19961-3 (Open Access)
Chemistry - A European Journal 2015, 21, 1609–1619. DOI: 10.1002/chem.201404926
Chemistry - A European Journal 2015, 21, 3425–3434. DOI: 10.1002/chem.201406110
Advances in Colloid and Interface Science 2015, 215, 1–12. DOI:10.1016/j.cis.2014.10.010
Dyes and Pigments 2014, 110, 97-105
DOI 10.1016/j.dyepig.2014.05.004 Accepted Author Manuscript (AAM)
Theranostics 2014, 4, 90-105, DOI:10.7150/thno.7088
Soft Matter 2013, 9, 10779-10790, DOI: 10.1039/ c3sm52092g (pdf)
Angewandte Chemie International Edition 2012, 51, 7541–7544
Journal of Colloid and Interface Science 2012, 370, 102–110 DOI: 10.1016/j.jcis.2011.12.037 (pdf) (Supplementary Information)
in Reviews in Fluorescence, volume 2009, 2011, 6, 23–45, ed. Chris D. Geddes, Springer, New York
Journal of Inclusion Phenomena and Macrocyclic Chemistry 2011, 70, 259-268
International Journal of Molecular Sciences 2010, 11, 173–188
Journal of Colloid and Interface Science 2010, 345, 369–376
Photochemical & Photobiological Sciences 2010, 9, 687–696
ChemPhysChem 2009, 10, 931–939
ChemPhysChem 2008, 9, 1819–1827
Journal of Physical Chemistry B 2007, 111, 3614-3624
Journal of Chemical Education 2007, 84, 1673-1675
Journal of the American Chemical Society 2005, 127, 8775-8784
Journal of Physical Chemistry B 2005, 109, 1364-1370
Supramolecular Chemistry 16, 549-559 (2004)
Supramolecular Chemistry 15, 207-211 (2003)
Steroids 68, 43-53 (2003)
Supramolecular Chemistry 15, 33-43 (2003)
Journal of Agricultural and Food Chemistry 51, 5036-5040 (2003)
Steroids 68, 55-64 (2003)
Journal of Physical Chemistry B 106, 9744-9752 (2002)
Journal of Agricultural and Food Chemistry 50, 108-112 (2002)
Supramolecular Chemistry 14, 397-404 (2002)
Applied Spectroscopy 2001, 55, 630–636
Journal of Physical Chemistry B 105, 5994-6003 (2001)
Angewandte Chemie, International Edition in English 39, 2856-2858 (2000)
Influence of pH on the stability of the inclusion complex of methyl orange and beta-cyclodextrin
Proceedings of the 9th International Symposium on Cyclodextrins, 1998, Santiago de Compostela, Spain.
Kluwer Academic Publishers, Dordrecht, 179-182 (1999)
Journal of Physical Chemistry 95, 10509-10518 (1991)
Journal of Physical Chemistry 95, 2022-2026 (1991)
Journal of Physical Chemistry 95, 10503-10509 (1991)
Chemical Physics Letters 174, 609-16 (1990)
Mechanistic studies of organic photoreactions utilizing proton tunnel effects
Physikalisch-Chemische Trenn- und Messmethoden 22, 109-18 (1990)
Instabilities and chaotic emission of far infrared ammonia lasers
Cambridge Studies in Modern Optics 1986, 4, 237–239