Wajih Al-Soufi

Full Professor

Tel.: 

+34 982 824 114

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Biographical sketch

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  • 1962 born in Hamburg, Germany.
  • 1982-1987 Degree in Physical Sciences in the Carolo-Wilhelmina University in Braunschweig and Georg-August University in Göttingen, Germany.
  • 1986-1988 Diploma Thesis in the Department of Spectroscopy of the Max-Planck Institute for Biophysical Chemistry in Göttingen (Dr. K.-H. Grellmann, Prof. Dr. A. Weller). 1988: “Diplom” in Physical Sciences in Göttingen.
  • 1988-1991 Ph.D. Thesis in the Department of Spectroscopy of the Max-Planck Institute for Biophysical Chemistry in Göttingen. "Blitzlichtphotolytische Untersuchungen von Tunneleffekten bei Wasserstoff-Umlagerungen im Triplettzustand" ("Study of the tunnel effect during hydrogen transfer in the triplet state using flash photolysis") (Dr. K.-H. Grellmann, Prof. Dr. J. Troe). 1991 Ph.D. in Chemistry in Göttingen.
  • 1992-1996 R&D Project Optical Sensors for Anesthesia, Drägerwerk AG, Medical Technology, (Lübeck, Germany).
  • 1996-2001 Assistant Professor for Physical Chemistry, USC, Lugo, Spain.
  • Since 2/7/2002 Associate Professor for Physical Chemistry, USC, Lugo, Spain.
  • 2015 National Accreditation as Full Professor (Acreditación National para Catedrático de Universidad), 5th of may, 2015
  • Since 2013 Founder and Technical Coordinator of the “Teaching Innovation Group XuvenCiencia” http://www.usc.es/xuvenciencia. “XuvenCiencia”, offers training to school staff, develops educational science kits and organizes one of the biggest annual scientific summer campus for young people in Spain.
  • 2023 Full Professor of Physical Chemistry

Participation in I+D projects

"Kinetische Untersuchungen von lichtinduzierten Proton-Tunnelprozessen" (´Kinetic investigation of photoinduced proton tunnel processes´), DFG, SFB-93, Max-Planck Institute of Biophysical Chemistry, Göttingen, Germany. 1986 - 1991, (Dr. Karl-Heinz Grellmann )

"Synthesis of new materials derived from cyclodextrins and study of its applications", CYTED, Spain, Chile, Brazil, Cuba, Costa Rica, Colombia and Uruguay, 1996 - 2000, (PI: José Vázquez Tato).

"Synthesis of derivatives of cyclodextrins and study of their aplications. Autoassociation of steroidic surfactants. ", PGIDT (PXI), 1999 – 2001, (José Vázquez Tato).

"Polymeric supramolecular derivatives of cyclodextrins and bile salts", PGIDT, Xunta de Galicia, 2001 – 2004, (PI: José Vázquez Tato).

"Structural study of organized media using proton transfer probes", Ministry for Education and science, MEC, CTQ2004-07683-C02-02, 2004 - 2007, (PI: Wajih Al-Soufi).

"Red temática de ciencias y materiales moleculares"
Xunta de Galicia, PGIDIT05PXI20901RT, 2005-2006, PI: Enrique Guitian Rivera

"Red temática de ciencias y materiales moleculares"
Xunta de Galicia, Consellería de Educación e Ordenación Universitaria
2006/124, 2006 - 2008, PI: Enrique Guitian Rivera

"Ayudas para la consolidación y estructuración de unidades de investigación competitivas del sistema gallego de I+D+I",
Xunta de Galicia, Consellería de Innovación e Industria
INCITE07PXI209034ES, 2007

"Fluorescent probes for the study of chemical processes in solution and in supramolecular systems. Applications of technological and biomedical interest",
Ministerio de Educación y Ciencia, CTQ2007-68057-C02-02/BQU,
2007 - 2010, PI: Wajih Al-Soufi

"Dynamics of the transport of mater through biomimetic membranes studied with single molecule fluorescence techniques"
Consellería de Economía e Industria, Xunta de Galicia, Incite09 262 304 PR, 2009-2012, PI: Wajih Al-Soufi

"Single-Molecule Fluorescence Detection for structural and dynamic studies of supramolecular systems of biomedical and technological interest". Ministerio de Ciencia e Innovación - CTQ2010-21369, 2010-2012,PI: Wajih Al-Soufi

"Consolidación e estruturación de unidades de investigación competitivas - REDES."
Consellería de Cultura, Educación e Ordenación Universitaria (2012-PG208) CN2012/314
2012-2014, IP Guitián Rivera,Enrique

"Ayudas para la consolidación y estructuración de unidades de investigación competitivas del sistema universitario de Galicia" Xunta de Galicia, ref. GPC2013/052, 2013–2015.

"Binding of Small Molecules to DNA: Dynamics, Photophysics and Conformations studied by Single-Molecule and Time-Resolved Fluorescence Spectroscopy", Proyectos de I+D+i, del programa estatal de investigación, desarrollo e innovación orientada a los retos de la sociedad, CTQ2014-59020-R, 01/01/2015 - 31/12/2017, IPs Al-Soufi, Wajih; Mosquera, Manuel

Ph. D. theses

"Supramolecular structures generated by cyclodextrins". Emilio Álvarez Parrilla. USC, 2000

"Complexation of biocides by cyclodextrins". Minerva Lezcano Brito. USC, 2002

"Structural and dynamic study of organized systems using fluorescent probes". Belén Reija Otero. USC, 2007

“Single-Molecule Fluorescence studies of the dynamics in supramolecular systems of biological interest”, Jorge Bordello Malde, USC, 2013

"Study of the association of supramolecular systems by fluorescence techniques: from cyclodextrins to beta-amyloids", Sonia Freire, USC, 2015

"Structural and dynamic study of supramolecular association processes", Lucas Piñeiro, USC, 2015

Diploma theses

"Study of the photophysical behavior of the 2-toluidin-6-naphtalensulphonate and its inclusion complexes with beta-cyclodextrin". Ana Íñigo Espiga. USC, 1999

"Aggregation of poligalacturonic acid". Maria Freire Rodriguez. USC, 2000

"Advanced analysis of time resolved spectra". Belén Reija Otero. USC, 2003

Seminars

"Fluorescence spectroscopy. Applications to physical chemistry and biological systems." Central University of "Marta Abreu" of Las Villas, Santa Clara, Cuba, October of 1999.

"Principal component analysis and global analysis of series of fluorescence spectra.", Seminar by invitation of the Cooperative Research Center SFB663, Heinrich-Heine Universität, Düsseldorf, August 2005

"Single Molecule Fluorescence Spectroscopy", II Iberian Photochemistry Course (CIF-II, July 23-24, 2007, Faro, Portugal)

"Supramolecular dynamics studied by fluorescence correlation spectroscopy", WORKSHOP ON SINGLE MOLECULE FLUORESCENCE IMAGING", Coordinator, Bilbao, España, 24/09/2009

Publications

CRISPR/Cas9 Delivery Systems to Enhance Gene Editing Efficiency

Ana Seijas, Diego Cora, Mercedes Novo, Wajih Al-Soufi, Laura Sánchez, Álvaro J. Arana

Amyloid Capture and Aggregation Inhibition by Human Serum Albumin

Diego Cora, Wajih Al‐Soufi, Mercedes Novo

International Journal of Biological Macromolecules, Volume 301, April 2025, 140367

https://doi.org/10.1016/j.ijbiomac.2025.140367

(Preprint: ChemRxiv, 2024, Version 1, 10.26434/chemrxiv-2024-fr8gt)

Thiazole Orange as fluorescent marker for the detection and quantification of dsDNA

Stella Hernández, Lucas Piñeiro, Wajih Al-Soufi, Mercedes Novo

ChemRxiv, 2024, Version 1, Preprint, 10.26434/chemrxiv-2024-lbxzx

Critical aggregation concentration and reversibility of amyloid-β (1–40) oligomers

Sara Illodo, Wajih Al-Soufi, Mercedes Novo

Archives of Biochemistry and Biophysics2024, 761, 110179, DOI 10.1016/j.abb.2024.110179

Mercedes Novo, Cibrán Pérez-González, Sonia Freire and Wajih Al-Soufi

Methods in Molecular Biology, 2023, 2551, 1–14. DOI: 10.1007/978-1-0716-2597-2_1

Mercedes Novo and Wajih Al-Soufi

Frontiers in Chemistry 2022, 10, 1042658. DOI: 10.3389/fchem.2022.1042658 (Open Access)

Sara Illodo, Cibrán Pérez-González, Ramiro Barcia, Flor Rodríguez-Prieto, Wajih Al-Soufi, Mercedes Novo

International Journal of Molecular Sciences 202223(2), 925. DOI: 10.3390/ijms23020925 (Open Access)

Wajih Al-Soufi, Jorge Carrazana-Garcia, and Mercedes Novo

Journal of Chemical Education 2020, 97, 9, 3090–3096, https://doi.org/10.1021/acs.jchemed.0c00745

Paul A. Dalgarno, José Juan-Colás, Gordon J. Hedley, Lucas Piñeiro, Mercedes Novo, Cibrán Pérez-González, Ifor D. W. Samuel, Mark C. Leake, Steven Johnson, Wajih Al-Soufi, J. Carlos Penedo, Steven D. Quinn

Scientific Reports 2019, 9, Article number: 12897, DOI: 10.1038/s41598-019-49210-0 (Open Access)

Mercedes Novo, Sonia Freire, Wajih Al-Soufi

Scientific Reports 2018, 8, Article number: 1783, DOI: 10.1038/s41598-018-19961-3 (Open Access)

Jorge Bordello, Mateo I. Sánchez, M. Eugenio Vázquez, José L. Mascareñas, Wajih Al-Soufi, and Mercedes Novo

Chemistry - A European Journal 2015, 21,  1609–1619. DOI: 10.1002/chem.201404926

Accepted Author Manuscript

Sonia Freire, Flor Rodríguez-Prieto, M. Carmen Ríos Rodríguez, J. Carlos Penedo, Wajih Al-Soufi, and Mercedes Novo

Chemistry - A European Journal 2015, 21,  3425–3434. DOI: 10.1002/chem.201406110

Accepted Author Manuscript

Lucas Piñeiro, Mercedes Novo, and Wajih Al-Soufi

Advances in Colloid and Interface Science 2015,  215, 1–12. DOI:10.1016/j.cis.2014.10.010

Author post-print and Supplementary Information

Sonia Freire, Marcus H. de Araujo, Wajih Al-Soufi, Mercedes Novo
Jesús Agulla, David Brea, Francisco Campos, Tomás Sobrino, Bárbara Argibay, Wajih Al-Soufi, Miguel Blanco, José Castillo, Pedro Ramos-Cabrer

Theranostics 2014, 4, 90-105, DOI:10.7150/thno.7088

Lucas Piñeiro, Sonia Freire, Jorge Bordello, Mercedes Novo, and Wajih Al-Soufi

Soft Matter 2013,  9, 10779-10790, DOI: 10.1039/ c3sm52092g (pdf)

Jorge Bordello, Mateo I. Sánchez, M. Eugenio Vázquez, José L. Mascareñas, Wajih Al-Soufi and Mercedes Novo

Angewandte Chemie International Edition 201251, 7541–7544

Wajih Al-Soufi, Mercedes Novo, Manuel Mosquera, and Flor Rodríguez-Prieto

in Reviews in Fluorescence, volume 2009, 2011, 6, 23–45,  ed. Chris D. Geddes, Springer, New York 

Mercedes Novo, Daniel Granadero, Jorge Bordello and Wajih Al-Soufi

Journal of Inclusion Phenomena and Macrocyclic Chemistry 2011, 70, 259-268

Daniel Granadero, Jorge Bordello, María Jesús Pérez-Alvite, Mercedes Novo, and Wajih Al-Soufi

International Journal of Molecular Sciences 2010, 11, 173–188

Jorge Bordello, Mercedes Novo and Wajih Al-Soufi

Journal of Colloid and Interface Science 2010, 345, 369–376

Sonia Freire, Jorge Bordello, Daniel Granadero, Wajih Al Soufi and Mercedes Novo

Photochemical & Photobiological Sciences 2010, 9, 687–696

J. Bordello, B. Reija, W. Al-Soufi, M. Novo

ChemPhysChem 2009, 10, 931–939

W. Al-Soufi, B. Reija, S. Felekyan, C. A. Seidel, M. Novo

ChemPhysChem 20089, 1819–1827

M. Novo, S. Felekyan, C. A. M. Seidel, and W. Al-Soufi

Journal of Physical Chemistry B  2007, 111, 3614-3624

Mercedes Novo, Belén Reija, Wajih Al-Soufi

Journal of Chemical Education 200784, 1673-1675

Wajih Al-Soufi, Belén Reija, Mercedes Novo, Suren Felekyan, Ralf Künemuth, and Claus A. M. Seidel

Journal of the American Chemical Society 2005, 127, 8775-8784

Belén Reija, Wajih Al-Soufi, Mercedes Novo, José Vázquez Tato

Journal of Physical Chemistry B 2005, 109, 1364-1370

Jorge Carrazana, Belén Reija, Pedro Ramos Cabrer, Wajih Al-Soufi, Mercedes Novo, José Vázquez Tato

Supramolecular Chemistry 16, 549-559 (2004)

Emilio Álvarez-Parrilla, Pedro Ramos Cabrer, Laura A. De La Rosa, Wajih Al-Soufi, F. Meijide, and José Vázquez Tato

Supramolecular Chemistry 15, 207-211 (2003)

Pedro Ramos Cabrer, Emilio Álvarez-Parrilla, Wajih Al-Soufi, Francisco Meijide, Eugenio Rodríguez Núñez, and José Vázquez Tato

Supramolecular Chemistry 15, 33-43 (2003)

Minerva Lezcano, Mercedes Novo, Wajih Al-Soufi, Eugenio Rodríguez-Núńez, and José Vázquez Tato

Journal of Agricultural and Food Chemistry 51, 5036-5040 (2003)

Aida Jover, Rosane M. Budal, Wajih Al-Soufi, Francisco Meijide, José Vázquez Tato, and Rosendo A Yunes

Steroids 68, 55-64 (2003)

Knut Rurack, Katrin Hoffmann, Wajih Al-Soufi, and Ute Resch-Genger

Journal of Physical Chemistry B 106, 9744-9752 (2002)

Minerva Lezcano, Wajih Al-Soufi, Mercedes Novo, Eugenio Rodríguez-Núńez, and José Vázquez Tato

Journal of Agricultural and Food Chemistry 50, 108-112 (2002)

Emilio Álvarez-Parrilla, Pedro Ramos Cabrer, Anand Pal Singh, Wajih Al-Soufi, Francisco Meijide, Eugenio Rodríguez Núńez, and José Vázquez Tato

Supramolecular Chemistry 14, 397-404 (2002)

W. Al-Soufi, M. Novo, and M. Mosquera

Applied Spectroscopy 2001, 55, 630636

Emilio Álvarez-Parrilla, Wajih Al-Soufi, Pedro Ramos Cabrer, Mercedes Novo, and José Vázquez Tato

Journal of Physical Chemistry B 105, 5994-6003 (2001)

Emilio Álvarez-Parrilla, Pedro Ramos Cabrer, Wajih Al-Soufi, Francisco Meijide, Eugenio Rodríguez Núńez, and José Vázquez Tato

Angewandte Chemie, International Edition in English 39, 2856-2858 (2000)

Influence of pH on the stability of the inclusion complex of methyl orange and beta-cyclodextrin

Carrazana García, J., Al-Soufi, W., Novo Rodríguez, M., and Vázquez Tato, J.

Proceedings of the 9th International Symposium on Cyclodextrins, 1998, Santiago de Compostela, Spain.
Kluwer Academic Publishers, Dordrecht, 179-182 (1999)

Heike Eisenberger, Bernhard Nickel, A. Andreas Ruth, Wajih Al-Soufi, Karl H. Grellmann, and Mercedes Novo

Journal of Physical Chemistry 95, 10509-10518 (1991)

W. Al-Soufi, A. Eychmueller, and K. H Grellmann

Journal of Physical Chemistry 95, 2022-2026 (1991)

Wajih Al-Soufi, Karl H. Grellmann, and Bernhard Nickel

Chemical Physics Letters 174, 609-16 (1990)

Mechanistic studies of organic photoreactions utilizing proton tunnel effects

Karl Heinz Grellmann, Wajih Al-Soufi, Ulrike Baron, Alexander Eychmueller, and Thomas Thomsen

Physikalisch-Chemische Trenn- und Messmethoden 22, 109-18  (1990)

Instabilities and chaotic emission of far infrared ammonia lasers

W. Klische, C. O. Weiss, W. Al-Soufi, G. Huettmann

Cambridge Studies in Modern Optics 1986, 4, 237–239