ECTS credits ECTS credits: 6
ECTS Hours Rules/Memories Student's work ECTS: 99 Hours of tutorials: 3 Expository Class: 24 Interactive Classroom: 24 Total: 150
Use languages Spanish, Galician
Type: Ordinary Degree Subject RD 1393/2007 - 822/2021
Departments: Morphological Science
Areas: Human Anatomy and Embryology
Center Faculty of Medicine and Dentistry
Call: First Semester
Teaching: With teaching
Enrolment: Enrollable | 1st year (Yes)
To know the cell as the basic unit on which the structure and function of the human body is based to ensure a correct understanding of the modifications that occur in pathological states.
INTEREST OF THE COURSE IN THE DEGREE OF MEDICINE
It is fundamental for any future doctor to acquire a deep knowledge of cell biology and human genetics (structure, function, and behavior of cells), since in today's medicine the different pathologies are considered as cellular and molecular dysfunctions.
PART I: CYTOLOGY
I. THE CELL: BASIC UNIT OF LIFE (1 hour)
Lesson 1: The cell: basic unit of life. Special cytology.
II. CELL SURFACE AND BIOMEMBRANES: PLASMA MEMBRANE. (6 hours)
Lesson 2: Extracellular environment
Lesson 3: Plasma Membrane: Concept and Generalities
Lesson 4: Mechanisms of permeability and transport of micromolecules through the membrane.
Lesson 5: Transport of macromolecules through the membrane: Endocytosis and exocytosis.
Lesson 6: Cell surface specializations.
III. HYALOPLASM AND SKELETON: CELLULAR FORM AND MOVEMENT (4 hours)
Lesson 7: Hyaloplasm. Concept and chemical composition. Cytoskeleton: concept and generalities.
Lesson 8: Microfilaments.
Lesson 9: Intermediate Filaments.
Lesson 10: Microtubules.
IV. CELL COMPARTMENT (6 hours)
Lesson 11: Endoplasmic reticulum.
Lesson 12: Golgi Apparatus.
Lesson 13: Lysosomes and Endosomes
Lesson 14: Energetic Organs: Peroxisomes and Mitochondria.
V. ORGANS THAT PROCESS INFORMATION: NUCLEUS AND RIBOSOMES (3 hours)
Lesson 15: Cellular nucleus: general characteristics
Lesson 16: Core in interface
Lesson 17: Nucleolus: structure and function Ribosomes. Proteasome.
VI. CELL CYCLE AND CELL DIVISION. (3 hours)
Lesson 18: The cell cycle.
Lesson 19: Mitosis.
Lesson 20: Meiosis.
PART II: GENETICS
VII. ORGANIZATION, TRANSMISSION AND EXPRESSION OF HEREDITARY MATERIAL: INHERITANCE PATTERNS (6 hours)
Lesson 21: Organization of the genome.
Lesson 22: Mendelian Inheritance Patterns
Lesson 23: Atypical inheritance patterns.
Lesson 24: Polygenic and Multifactorial Inheritance
VIII. GENETIC MATERIAL CHANGES (6 hours).
Lesson 25: Genetic variation: Mutation.
Lesson 26: Chromosomal alterations.
Lesson 27: Mendelian populations.
Lesson 28: Polymorphisms.
Lesson 29: Genetic counselling.
Lesson 30: Genetic Basis of Cancer.
INTERACTIVE LESSONS
Laboratory practices: (12 hours)
P1: The optical microscope: Nomenclature and instructions for use
P2-3 Preparation and staining of a blood extension for the study of free cells
P4-5 Staining of sections for the study of associated cells
P6: Microscopic study of the stains carried out in previous practices.
P7: The cell: general characteristics and cell surface: Microscopic study of intestine, trachea and skin preparations.
P8: Microscopic study of myofilament preparations.
P9: Microscopic study of Golgi Complex and endoplasmic reticulum demonstration slides.
P10: Microscopic study of demonstrative slides of mitosis and meiosis
P11- Metaphasic chromosomes. Observation of the Barr corpuscle
P12: ABO system. Determination of blood group
Computer Practice (4 hours)
P13-P14: Academic group work
P15-P16: Academic group work
Seminars (4 hours)
S1: Origin of the cell.
S2: Cell death: Necrosis and Apoptosis
S3: Genetic problems and games
S4: Genetic problems and games
BASIC BIBLIOGRAPHY.
1 CALVO A. Biología Celular Biomédica. 1st ed. Elsevier; 2015.
2 JORDE LB, CAREY JC, BAMSHAD MJ. Genética Médica. 5th ed. Elsevier; 2016.
3 KARP G. Biología celular y molecular. Conceptos y experimentos. 7th ed. McGraw-Hill; 2017.
4 NUSSBAUM RL, MCINNES RR, WILLARD HF. THOMPSON & THOMPSON. Genética en Medicina. 8th Ed. Elsevier Masson; 2016.
5 PANIAGUA R. Biología celular y molecular. 4th ed. McGraw-Hill; 2017.
6 TURNPENNE P, ELLARD S. EMERY. Elementos de genética médica 15th ed. Elsevier. 2018.
COMPLEMENTARY BIBLIOGRAPHY:
1 ALBERTS B, BRAY D, LEWIS J, RAFF M, ROBERTS K, WATSON J. Biología Molecular de la Célula. Omega; 2016.
2 KIERSZENBAUM AL, TRES LL. Histología y Biología Celular. Introducción a la anatomía patológica. 4th ed. Elsevier; 2016.
3 LODISH H, BERK A, KAISER CA, KRIEGER M, BRETSCHER A, PLOEGH H, AMON A, SCOTT MP. Biología Celular y Molecular. 6th ed. Médica Panamericana; 2016.
4 PIERCE BA. Genética: un enfoque conceptual. 5th ed. Médica Panamericana; 2016.
GENERAL COMPETENCIES (GC)
This course helps to reinforce many of the basic skills of the degree:
GC5. Recognizing one's own limitations and the need to maintain and update one's professional competence, paying special attention to the autonomous learning of new knowledge and techniques and to motivation for quality.
GC6. To develop professional practice with respect to other health professionals, acquiring teamwork skills.
GC7 Understanding and recognizing the normal structure and function of the human body, at the molecular, cellular, tissue, organic and systems level, in the different stages of life and in both sexes.
GC9. Understand and recognize the effects, mechanisms and manifestations of disease on the structure and function of the human body,
GC23 Communicating effectively and clearly, both orally and in writing.
GC31 Knowing, critically evaluating and understand how to use clinical and biomedical information sources to obtain, organize, interpret and communicate scientific and health information.
GC36 To be able to formulate hypotheses, to collect and to value of form critical the information for the resolution of problems, following the scientific method.
GC37 To acquire the basic formation for the research activity.
MODULE I SPECIFIC COMPETENCES (MISC)
MISC.01 To know the structure and function of cells: Cellular membranes and morphological differentiations of cellular communication. The cytoskeleton as responsible for the shape and movement of cells. The endomembrane system and the energetic organelles
MISC.06 Cellular Communication
MISC.08.- Cell cycle.
MISC.09.- Cell differentiation and proliferation.
MISC.10.- Gene information, expression, and regulation.
MISC.11.- Inheritance: Genetic information, expression and regulation and its transmission through the different models of inheritance
MISC.18.- Handling of material and basic laboratory techniques.
MISC.20.- Recognize with macroscopic and microscopic methods and image techniques the morphology and structure of tissue, organs, and systems.
Scenario 1:
In the lectures, the fundamental contents of the program will be explained using visual aids (optical and electronic microcopy images, diagrams and/or animations or videos). The lectures will take place in the classrooms of the Faculty of Medicine.
In the laboratory practices, students will be initiated in the use of basic techniques for the study of the cell. In the seminars and in the computer practices, the topics and contents of the course will be worked on using mainly cooperative work techniques.
The interactive lessons will be given mainly in the classrooms and laboratories of the Faculty of Medicine. Some contents (10% of the hours) will be taught using corporate telematic tools such as: Campus Virtual-Moodle, Microsoft Teams, Microsoft Forms...
The course will have a virtual classroom at the Campus Virtual in which students will be able to have didactic material and digitalized images of support. In addition, a public tutoring forum will be established in the Campus Virtual.
Scenario 2:
Face-to-face and remote teaching will be combined to promote the social distancing measures in force at that time. To this end, institutional tools and platforms will be used (Campus Virtual, Teams...)
Scenario 3:
Teaching will be exclusively virtual, using institutional tools and platforms (Campus Virtual, Teams...).
Scenarios 1 and 2
The final tests will have PRESENTIAL CHARACTERISTICS
In the evaluation of the competencies, the knowledge, skills, and abilities acquired by the students throughout the course will be assessed.
The evaluation system will be applicable to each of the possible scenarios for the two opportunities.
The evaluation of the lectures will be 70% of the final grade and the interactive part will be 30%.
The evaluation will be carried out continuously (30% of the grade) thus assessing the student's daily work throughout the course and by means of a final test complementary to the continuous evaluation (70% of the grade).
- The continuous evaluation is based on the performance of different activities, which will be programmed and announced in the virtual campus. These activities will be carried out both in person and online, and the participation of students and the completion of the activity will be monitored.
- The final evaluation test will consist of an exam that will be tailored to the particularities of the scenario and subject, and could include different types of questions (such as multiple choice and single answer questions, short-answer questions, assay questions, clinical cases...)
The different tests and/or activities may be replaced by telematic tests, both synchronous and asynchronous, using the resources of the institutional platforms (Virtual Classroom-Moodle and Microsoft Teams...)
Final Exam Continuous Evaluation TOTAL
Expository teaching 60% 10% 70%
Interactive teaching 10% 20% 30%
The requirements for passing the course are: 1) to obtain 50% of the score in the final test, and 2) to have carried out 80% of the interactive activities.
"In the case of fraudulent exercises or tests, the rules for evaluating the academic performance of students and reviewing grades will apply.
Scenario 3
In this case the evaluation tests will be replaced by telematic non-presential tests, which will favour the security of students and teachers, by using the resources of the institutional platforms (Virtual Classroom-Moodle and Microsoft Teams...)
The final tests will be carried out using resources that guarantee the identification of the student, as well as the personal nature of the test. If the technical means are not available to guarantee the fulfilment of these premises, an oral final test could be used
PRESENTIAL WORK IN THE CLASSROOM: 60 Hours
Lectures: 36
Interactive lessons: 20
Tutorials in small groups or individualized: 2
Exams to be taken: 2
STUDENT PERSONAL WORK: 90 Hours
Individual study: 75
Preparation of internship reports: 5
Elaboration of works: 10
It is recommended to take notes in class during the lessons (both if they are face-to-face or telematic) and to expand them with the didactic material available in the virtual campus and/or with the recommended bibliography, available through the library both in paper format and through digital access. It is advisable to study the contents daily and to use the individual tutorials and the public tutorial forum to solve doubts.
It is advisable to carry out a self-evaluation process, guided by the results of the continuous assessment, to learn how to critically evaluate the level of one's own knowledge and skills.
"Contingency Plan"
In all three scenarios, teaching will be complemented by content published on the Virtual Campus, which will include material explaining the contents of the course, complementary student support material and a public tutoring forum
Scenario 1
It will be based mainly on teaching and evaluation in person, with support from the Virtual Campus that allows for asynchronous communication between students and teachers
Scenario 2
Teaching methodology
Face-to-face and remote teaching will be combined in order to promote the social distancing measures in force at that time. To this end, institutional tools and platforms will be used (Campus virtual and Microsoft Teams)
Evaluation system
Evaluation preferably in person. The resources of the institutional platforms (Campus virtual and Microsoft Teams) may also be used for continuous evaluation
Scenario 3
Teaching methodology
The teaching will be exclusively virtual, using the institutional tools and platforms (Virtual Classroom-Moodle and Microsoft Teams)
Evaluation system
The final tests will be carried out using resources that guarantee the identification of the student, as well as the personal nature of the test. If the technical means are not available to guarantee the fulfilment of these premises, an oral final test could be used.
In the case of fraudulent exercises or tests, the provisions of the Normativa de evaluación del rendimiento académico de los estudiantes y de revisión de calificaciones shall apply
Maria Josefa Natividad Guerra Seijas
- Department
- Morphological Science
- Area
- Human Anatomy and Embryology
- Phone
- 881812209
- mjosefanativid.guerra [at] usc.es
- Category
- Professor: University Professor
Maria Begoña Villar Cheda
- Department
- Morphological Science
- Area
- Human Anatomy and Embryology
- Phone
- 881812299
- bego.villar [at] usc.es
- Category
- Professor: Temporary PhD professor
Juan Andres Parga Martin
Coordinador/a- Department
- Morphological Science
- Area
- Human Anatomy and Embryology
- juan.parga [at] usc.es
- Category
- Professor: LOU (Organic Law for Universities) PhD Assistant Professor
Rita Valenzuela Limiñana
- Department
- Morphological Science
- Area
- Human Anatomy and Embryology
- rita.valenzuela [at] usc.es
- Category
- Professor: LOU (Organic Law for Universities) PhD Assistant Professor
Maria Angeles Pedrosa Sanchez
- Department
- Morphological Science
- Area
- Human Anatomy and Embryology
- mangeles.pedrosa [at] rai.usc.es
- Category
- Xunta Pre-doctoral Contract
| Monday | |||
|---|---|---|---|
| 09:30-10:30 | Grupo /CLE_02 | Spanish | Medicine-Classroom 5 |
| 16:30-17:30 | Grupo /CLE_04 | Spanish | Medicine-Classroom 5 |
| 19:30-20:30 | Grupo /CLE_03 | Spanish | Medicine-Classroom 4 |
| Tuesday | |||
| 12:30-13:30 | Grupo /CLE_02 | Spanish | Medicine-Classroom 5 |
| 16:30-17:30 | Grupo /CLE_03 | Spanish | Medicine-Classroom 4 |
| 19:30-20:30 | Grupo /CLE_04 | Spanish | Medicine-Classroom 5 |
| Wednesday | |||
| 09:30-10:30 | Grupo /CLE_02 | Spanish | Medicine-Classroom 5 |
| 16:30-17:30 | Grupo /CLE_04 | Spanish | Medicine-Classroom 5 |
| 19:30-20:30 | Grupo /CLE_03 | Spanish | Medicine-Classroom 4 |
| Thursday | |||
| 12:30-13:30 | Grupo /CLE_02 | Spanish | Medicine-Classroom 5 |
| 16:30-17:30 | Grupo /CLE_03 | Spanish | Medicine-Classroom 4 |
| 19:30-20:30 | Grupo /CLE_04 | Spanish | Medicine-Classroom 5 |
| Friday | |||
| 09:30-10:30 | Grupo /CLE_02 | Spanish | Medicine-Classroom 5 |
| 16:30-17:30 | Grupo /CLE_04 | Spanish | Medicine-Classroom 5 |
| 19:30-20:30 | Grupo /CLE_03 | Spanish | Medicine-Classroom 4 |
| 01.16.2021 09:00-12:00 | Grupo /CLE_01 | Dentistry-Classroom 1 |
| 01.16.2021 09:00-12:00 | Grupo /CLE_01 | Dentistry-Classroom 2 |
| 01.16.2021 09:00-12:00 | Grupo /CLE_01 | Dentistry-Classroom 4 |
| 01.16.2021 09:00-12:00 | Grupo /CLE_01 | Medicine-Castelao Classroom |
| 01.16.2021 09:00-12:00 | Grupo /CLE_01 | Medicine-Classroom 1 |
| 01.16.2021 09:00-12:00 | Grupo /CLE_01 | Medicine-Classroom 2 |
| 01.16.2021 09:00-12:00 | Grupo /CLE_01 | Medicine-Classroom 3 |
| 01.16.2021 09:00-12:00 | Grupo /CLE_01 | Medicine-Classroom 4 |
| 01.16.2021 09:00-12:00 | Grupo /CLE_01 | Medicine-Classroom 5 |
| 01.16.2021 09:00-12:00 | Grupo /CLE_01 | Medicine-Classroom 6 |
| 01.16.2021 09:00-12:00 | Grupo /CLE_01 | Medicine-Classroom 7 |
| 01.16.2021 09:00-12:00 | Grupo /CLE_01 | Medicine-Classroom 8 |
| 01.16.2021 09:00-12:00 | Grupo /CLE_01 | Medicine-Classroom 9 |
| 07.10.2021 12:30-14:30 | Grupo /CLE_01 | Medicine-Classroom 4 |
| 07.10.2021 12:30-14:30 | Grupo /CLE_01 | Medicine-Classroom 5 |
| 07.10.2021 12:30-14:30 | Grupo /CLE_01 | Medicine-Classroom 7 |
| 07.10.2021 12:30-14:30 | Grupo /CLE_01 | Medicine-Classroom 8 |