ECTS credits ECTS credits: 6
ECTS Hours Rules/Memories Student's work ECTS: 99 Hours of tutorials: 3 Expository Class: 24 Interactive Classroom: 24 Total: 150
Use languages Spanish, Galician
Type: Ordinary Degree Subject RD 1393/2007 - 822/2021
Departments: Physical Chemistry
Areas: Physical Chemistry
Center Faculty of Pharmacy
Call: Second Semester
Teaching: Sin docencia (Extinguida)
Enrolment: No Matriculable | 1st year (Yes)
To provide with a theoretical foundation to the knowledge of chemistry to the students, more wide and rigorous than the proceeding one of the general chemistry.
To show the form in which this foundation allows to approach problems of certain level of complexity belonging to the area of the chemistry, the biology, the medicine and the pharmacology.
To acquaint the students with experimental procedures directly related to the discipline.
Block One
Lesson 1.
General condition of phase equilibrium. Intensive independent variables: The phase rule. Phase equilibrium in systems of a component: phase diagrams. Equations of Clapeyron and Clausius-Clapeyron.
Block Two
Lesson 2.
Phase equilibrium in multicomponent systems. Liquid mixtures of volatile, miscible components in all the proportions, in equilibrium with his vapor. Ideal solutions: Raoult's Law; pressure - composition and temperature - composition diagrams. Nonideal solutions: Henry's Law (dissolution of a gas in a liquid); pressure - composition and temperature - composition diagrams. Distillation of immiscible liquids in equilibrium with his vapor: steam distillation.
Lesson 3
Molecular interpretation of the behavior of the solutions. Expressions of the chemical potentials of the components in mixtures of miscible components in ideal and nonideal solutions: activity and activity coefficient. Expressions of the chemical potentials of components with limited solubility.
Lesson 4
Solutions of involatil solute: colligative properties. Vapor-pressure lowering. Boiling-point elevation and freezing-point depression. Osmosis and osmotic pressure. The osmosis in Biology and in Pharmacy. Colligative properties in solutions of electrolytes. Applications of the colligative properties to the determination of molecular masses. Distribution of a solute between two immiscible liquids: partition coefficient.
Block Three
Lesson 5
Chemical equilibrium. Thermodynamic condition of equilibrium. Chemical equilibrium in gaseous phase. Chemical equilibrium in solution. Heterogeneous chemical equilibrium. Factors that modify the condition of chemical equilibrium: influence of the pressure, temperature and the addition of reactant or inert components. The reaction quotient like criterion of spontaneity and equilibrium: the isotherm of reaction.
Lesson 6
Equilibrium in electrolyte solutions. Solubulity product. Mean ionic activity coefficient: Debye-Hückel equation. Ionic strength. Experimental results of the measures of the mean ionic activity coefficient. Influence of the common ion and neutral salts on the solubility of slightly soluble salts.
Equilibrium dissociation of monoprotics weak acids and bases. Autodissociation of the water. Dissociation of amino acids and proteins: isoelectric point.
"Química ´Física”. T. Engel y P. Reid. Ed. Addison-Wesley
"Fisicoquímica para Farmacia y Biología". P. Sanz y otros. Ediciones Científicas y Técnicas S.A., SALVAT.
"Fisicoquímica". I. N. Levine. Ed. McGraw-Hill.
"Fisicoquímica". P. W. Atkins. Ed. Addison-Wesley Iberoamericana.
"Fisicoquímica". D.W. Ball. Ed. Thomson.
FM01.-To apply the knowledge of Physics and Mathematics to the pharmaceutical sciences.
Q05.- Knows the physical-chemistry characteristics of the substances used for the manufacture of the medicaments.
Q06.- Knows and to understand the characteristics of the reactions in solution, the different states of the matter and the principles of the thermodynamic and his application to the pharmaceutical sciences.
TF03.- Knows the processes of liberation, absorption, distribution, metabolism and excretion of medicaments, and factors that determine the absorption and disposition depending on his routes of administration.
TF05.- Knows the physical-chemistry and biopharmaceutical properties of the active principles and exicipients as well as the possible interactions between both.
MF01.- To use of sure form the medicaments bearing in mind his physical and chemical properties including any risk associated with his use.
CP01.- Critical and self-critical capacity.
CI01.- Analysis and synthesis skills
CP05.- Aptitude to communicate with experts of other areas.
They will be used:
-Large group lectures: lectures taught by the teacher in which the fundamental theoretical contents of the subject are presented, also raising and carrying out basic problems of application.
In addition, complementary activities that the student must do are proposed: study of additional theoretical contents not included in these classes, individual realization of numerical problems and other individual or group activities.
Scenario 1: they will be performed in person.
Scenario 2: they will be performed in a telematic and synchronous way.
Scenario 3: they will be performed telematically and synchronously or asynchronously depending on the means of connection of teachers and students.
- Interactive classes in small groups: Theoretical/practical class in which doubts and applications of the theory are proposed and solved, problems, exercises, … The student actively participates in these classes in different ways: delivery of exercises to the teacher (some of those proposed in the problem bulletins that the teacher gives to the students well in advance); resolution of exercises in the classroom, sessions related to some cooperative learning raised, etc. Attendance at these interactive small group classes will be mandatory.
Scenario 1: they will be performed in person.
Scenario 2: they will be performed in person.
Scenario 3: they will be performed telematically and synchronously or asynchronously depending on the means of connection of teachers and students
-Board tutorials, face-to-face, in a very small group: -Tutorials programmed by the teacher Activities are proposed such as clarification of doubts about theory, problems, exercises, readings or other proposed tasks.
Scenario 1: will be performed in a classroom setting.
Scenario 2: will be performed in a classroom setting.
Scenario 3: they will be performed in a telematic way and in a synchronous or asynchronous way depending on the means of connection of teachers and students
-Laboratory practice classes: Classes that take place in a practice laboratory. In them the student acquires the skills of the work in a laboratory and consolidates the knowledge acquired in the theory classes.
Scenario 1: The student must attend each session of practices in a face-to-face way and, after the realization of the experiences and calculations necessary for the achievement of the objectives, they will collect in the laboratory notebook the development of the practice and the calculations and results that come, presenting istes for evaluation.
Scenario 2: The student will attend 50% of the practice sessions in person and will receive the rest in a virtual synchronous way. After the realization of the experiences and calculations necessary for the achievement of the objectives, they will collect in the laboratory notebook the development of practice and the calculations and obtained results, presenting them for evaluation.
Scenario 3: The student will receive 100% of the virtual practices (synchronous and asynchronous, a combination of both) through the display of videos and activities to be performed on them.
The global qualification in the 1st call of the course, will be the result of adding the one obtained in the theory and problems exam plus the corresponding one in the continuous evaluation and the one obtained in the laboratory practices. The fact that the practices have not been carried out and approved will mean that the qualification obtained by the student will be the not-presented.
The theory exam will consist of several applied questions with several sections, alone or combined with a test. The problems exam will consist of two problems with different sections.
The final exam of the subject will be done in person or by telematic means depending on the health situation.
The maximum score that can be achieved in the theory and problems exam will depend on the work scenario:
Scenario 1: a maximum of 8 points, with 5.5 points corresponding to theory and the remaining 2.5 to problem scores.
Scenario 2: a maximum of 6 points, corresponding to 4 points for theory and the remaining 2 for problem scores.
Scenario 3: a maximum of 5 points, corresponding to 3.5 points for theory and the remaining 1.5 for problem notes.
Regardless of the work scenario, to pass the subject the student must have at least 35% of the theory grade (counting only the theory part of the exam or the theory part of the exam plus the continuous assessment, according to work scenario) and at least 40% of the problem grade (counting only the problem part of the exam or the problem part of the exam plus the continuous assessment, according to work scenario).
The maximum score for continuous assessment will be 1.5 points (scenario 1), 3.5 points (scenario 2) and 4.5 points in scenario 3. It will be established accounting for the active participation of the student in the interactive classes, the performance of the proposed activities, atendance to tutorial classrooms, the scores attained for written tests on particular sections that could be performed, etc. To be able to access the qualification corresponding to the continuous evaluation, attendance (in person or virtually) at the interactive classes is a prerequisite.
To evaluate the laboratory practices, with a maximum score of 0.5 points, an exam will be performed at the end of the practices (face-to-face in scenarios 1 and 2, and by telematic means in scenario 3), with a maximum score of 0.4 points, which be added to a maximum of 0.1 points attained in the evaluation of the laboratory notebook. Students who repeat the course will not have to do it again, if they do not want to, and in this case, the maximum 0.5 points of the qualification of the practices will only be counted in the global note of the year of its accomplishment, and in the remaining courses the 0.5 points will be incorporated to the percentage assigned to the corresponding continuous evaluation according to the work scenario. In the 2nd call of the academic year, only the theory and problems exam will be taken, keeping the qualification corresponding to the practices and the continuous assessment obtained during the course. The maximum marks on which these two parts of the exam will be graded and the minimum marks required in each of them will be the same as those described for the first convocation. The requirements of having completed and approved the internship and having covered the mandatory attendance (in person or online depending on the scenario) and interactive classes during the course must also be maintained.
The skills acquired in the course will be assessed through the following channels: review: specific skills: FM01, Q05, Q06, TF03 FT05 and skills: CP01 and CI01. In interactive classes: specific skills: FM01, Q05, Q06, TF03, FT05 and MF01 and skills: CP01, CI01 and CP05. Laboratory practices: specific skills: Q05, Q06, FT05 and MF01 and skills: CP01 and CI01
WORK IN PERSON IN THE CLASSROOM (60 HOURS)
- Expositive lessons: 30 hours
- Interactive lessons of blackboard: 15 hours
- Interactive lessons of laboratory works: 9 hours
- Tutorships (very reduced group): 2.5 hours
- Exámen of theory and problems and its review: 3.5 hours
PERSONAL WORK OF THE STUDENT (90 HOURS)
- Expositive lessons (individual freelance study or in a group): 48 hours
- Interactive lessons of blackboard (resolution of financial years, or other works): 24 hours
- Interactive lessons of laboratory works (previous and analysis preparation later of the
obtained results): 6.5 hours
- Tutorships (doubts orientation and resolution): 2.5 hours
- Preparation of examinations: 9 hours
Revision and putting in the day of mathematics (infinitesimal calculation and analytical geometry), physics (mechanics, electricity, systems of units) and general chemistry.
Regular dedication to the study of the subject (short periods daily newspapers or every two days, better than weekly).
To avoid to introduce in a chapter without reaching a certain degree of understanding of the previous one.
To dedicate a special effort to the comprehension of the meaning or nature of some theoretical strategic contents, as well as to the general methods of resolution of the problems.
The virtual platform of the USC will be in use as support and complement of the theoretical - practical teaching and as an important element of communication with the student. Depending on the work scenario, it will be used with greater or lesser intensity.
Carlos Vazquez Vazquez
- Department
- Physical Chemistry
- Area
- Physical Chemistry
- Phone
- 881813011
- carlos.vazquez.vazquez [at] usc.es
- Category
- Professor: University Lecturer
Ana Maria Rios Rodriguez
- Department
- Physical Chemistry
- Area
- Physical Chemistry
- Phone
- 881814210
- anamaria.rios [at] usc.es
- Category
- Professor: University Lecturer
Luis Cid Rey
- Department
- Physical Chemistry
- Area
- Physical Chemistry
- Phone
- 881814911
- luismaria.cid [at] usc.es
- Category
- Professor: University Lecturer
Matilde Casas Parada
Coordinador/a- Department
- Physical Chemistry
- Area
- Physical Chemistry
- Phone
- 881815255
- matilde.casas [at] usc.es
- Category
- Professor: University Lecturer
Juan Carlos Garcia Monteagudo
- Department
- Physical Chemistry
- Area
- Physical Chemistry
- Phone
- 881814915
- juancarlos.garcia [at] usc.es
- Category
- Professor: University Lecturer
| Wednesday | |||
|---|---|---|---|
| 10:00-11:00 | Grupo A1/CLIS_01 | Spanish | 5035 Animal Physiology Seminar Room |
| 12:10-13:10 | Grupo B1/CLIS_04 | Galician, Spanish | 5035 Animal Physiology Seminar Room |
| 18:30-19:30 | Grupo C1 /CLIS_07 | Spanish | 5035 Animal Physiology Seminar Room |
| Thursday | |||
| 10:00-11:00 | Grupo A2/CLIS_02 | Spanish | 5035 Bromatology Seminar Room |
| 12:10-13:10 | Grupo B2/CLIS_05 | Spanish, Galician | 5035 Bromatology Seminar Room |
| 18:30-19:30 | Grupo C2/CLIS_08 | Spanish | 5035 Bromatology Seminar Room |
| Friday | |||
| 10:00-11:00 | Grupo A3/CLIS_03 | Spanish | 5035 Inorganic Chemistry Seminar Room |
| 12:10-13:10 | Grupo B3/CLIS_06 | Galician, Spanish | 5035 Inorganic Chemistry Seminar Room |
| 18:30-19:30 | Grupo C3/CLIS_09 | Spanish | 5035 Inorganic Chemistry Seminar Room |