ECTS credits ECTS credits: 6
ECTS Hours Rules/Memories Student's work ECTS: 99 Hours of tutorials: 3 Expository Class: 24 Interactive Classroom: 24 Total: 150
Use languages Spanish, Galician
Type: Ordinary Degree Subject RD 1393/2007 - 822/2021
Departments: Physical Chemistry
Areas: Physical Chemistry
Center Faculty of Pharmacy
Call: First Semester
Teaching: Sin docencia (Extinguida)
Enrolment: No Matriculable | 1st year (Yes)
- Elementary use of intermolecular interactions as a way of explaining and predicting the structure and properties of simple material systems. Extrapolation, in a qualitative way, of these contents to more complex systems (specifically biological systems).
- Knowledge of the nature of transport properties, mainly the diffusion. Elementary treatment of this one and its application in fields related to the Pharmacy Degree (Biochemistry, Pharmacology and Pharmaceutical Technology).
- Knowledge of Formal Chemical Kinetics, aimed to its later use in Biochemistry, Pharmacology and Pharmaceutical Technology.
- Achieve an adjustment of the students to the handling of abstract concepts, like those utilised in the classical thermodynamics, and its use for the study of chemical phenomena.
BLOCK I:
Lesson 1: Action of an electric field on polar and unpolar molecules: dipolar moment and polarizability. Intermolecular forces of attraction: dipole-dipole interactions, dipole - induced-dipole interactions and dispersion forces. Hydrogen bonds. Intermolecular repulsive forces. Lennard-Jones potential. Relationship with the thermodynamic properties. General features of the polymers.
BLOCK II:
Lesson 2: Objectives of the Thermodynamics. State and state variables. Thermodynamical terminology: types of systems and processes. Equilibrium and nonequilibrium states. Heat and work: sign criterion and units. Thermodynamically reversible and irreversible processes.
Lesson 3: First Principle of the Thermodynamics; internal energy concept. Exchanges of heat at constant volume and pressure: concept of enthalpy. Internal energy and enthalpy variations with the temperature: concept of heat capacity. Constant pressure and constant volume heat capacities. Variation of the heat capacities with the temperature
Lesson 4: Thermochemistry: heat of reaction. Thermochemiscal equations. Thermochemical laws. Normal heat of reaction: conventional enthalpies. Variation of the heat of reaction with the temperature: Kirchoff’s Equation.
Lesson 5: Spontaneous processes. The Second Principle of the Thermodynamics. The concept of entropy. Variation of entropy in reversible and irreversible processes: inequality of Clausius. The variation of entropy as a spontaneity criterion.
Lesson 6: Functions of Gibbs and Helmholtz: its physical meaning. Its use as a criterion of spontaneity. Variation of Gibbs free energy with pressure and temperature: Gibbs-Helmholtz equation
BLOCK III:
Lesson 7: Partial molar quantities. The fundamental equation of chemical thermodynamics and the concept of chemical potential. Physical meaning of chemical potential. Variation of chemical potential with pressure and temperature. General condition of material balance
BLOCK IV:
Lesson 8: Chemical kinetics: generalities. Rate of reaction. Rate equation. Order of reaction. Rate constant: concept and units. Integration of the simpler rate equations. Time necessary to reaching a certain degree of advance: time of semi reaction. Methods of calculation of the kinetic parameters. Effect of the temperature: equation of Arrhenius.
Lesson 9: Elementary Reactions. Opposed reactions. Parallel reactions. Consecutive reactions: the stationary state approach. Catalysis: generalities.
Lesson 10: Transport properties: generalities. Diffusion: laws of Fick. Viscosity: law of Newton. Non Newtonian fluids. Rheological properties of the polymers.
"Química ´Física”. T. Engel y P. Reid. Ed. Addison-Wesley
"Fisicoquímica para Farmacia y Biología". P. Sanz y otros. Ediciones Científicas y Técnicas S.A., SALVAT.
"Fisicoquímica". I. N. Levine. Ed. McGraw-Hill.
"Fisicoquímica". P. W. Atkins. Ed. Addison-Wesley Iberoamericana.
"Fisicoquímica". D.W. Ball. Ed. Thomson.
- FM01.- Apply of Physics and Mathematics knowledge to pharmacy sciences.
-Q05.- Know the physical and chemical characteristics of substances utilised for the manufacture of drugs.
- Q06.- Know and understand the characteristics of the reactions in dissolution, the matter states and the principles of thermodynamics and its application to the pharmaceutical sciences.
- TF03.- Know the liberation, absorption, distribution, metabolism and excretion of drugs, and factors that condition the absorption according to its administration routes.
- TF05.- Know the physical chemical and biofarmaceutical properties of the active ingredients and excipients of drugs as well as the possible interactions between both.
- MF01.-Safe use of drugs taking into account its physical and chemical properties including any associated risk.
- CP01.- Critical skill and self-criticism.
- CI01.- Analysis and synthesis skills
- CP05.- Skills to communicate with experts of other areas.
Will be used:
-Expositive lessons in a big group: Face-to-face lessons given by the teacher in which fundamental theoretical contents of the matter are explained and are proposed basic problems related with its application.
Additionally, complementary activities are proposed to be performed by the students: study of parts not included in the expositive lessons, individual performance of numerical problems and other individual or group activities.
- Interactive lessons in reduced groups: Theoretical and practical face-to-face lessons in which the students solve several types of doubts. The students must participate actively in different ways: delivery of exercises to the teacher (some previously proposed through bulletins delivered to students); resolution of exercises in the classroom, some cooperative learning sessions, etc. The assistance to these interactive lessons in reduced groups will be compulsory.
- Face-to face blackboard tutorships in a very reduced group programmed by the teacher. They set out to activities as the clarification of doubts on theory, problems, exercises, readings or other proposed tasks.
The overall rating in the 1st call for the course, will be the result of the sum of that obtained in the examination of theory and problems plus the one corresponding to the continuous assessment.
The theoretical exam will consist of a series of short applied questions with several sections. Also the final exam will consist of two problems. Both exams will be face-to-face.
The maximum rating in theory and problems will be 8 points, corresponding 5.5 points to the note of theory and the 2.5 remaining points to the note of problems. A special requirement to pass the course is to obtain a note equal to or more than 2 points in theory and equal to or more than 1 points in problems.
The maximum rating of continuous assessment is 2 points and will be established taking into account: the active involvement of the student in the interactive lessons, proposed activity performance, assistance to tutorships, notes corresponding to written proofs on specific sections, etc. In order to be able to access the rating corresponding to the continuous assessment, is necessary the prerequisite of the assistance to interactive lessons.
Repeating students who wish to do so, may maintain the qualification of the continuous assessment corresponding to the previous course without having to attend interactive classes, being indispensable requirement having signed, at the beginning of the semester, a proof of this commitment with the professor in charge of the subject.
In the 2nd call for the academic course, just will be made the examination of theory and problems, keeping the rating obtained in continuous assessment during the course. The same proportions earlier remarked and the same prerequisites to pass the course will be applied.
The skills acquired in the course will be assessed through the following channels: review: specific skills: FM01, Q05, Q06, TF03 FT05 and skills: CP01 and CI01. In interactive classes: specific skills: FM01, Q05, Q06, TF03, FT05 and MF01 and skills: CP01, CI01 and CP05
WORK IN PERSON IN THE CLASSROOM (60 HOURS)
- Expositive lessons: 30 hours
- Interactive lessons: 24 hours
- Tutorships (very reduced group): 2.5 hours
- Examination of theory and problems and its review: 3.5 hours
PERSONAL WORKOF THE STUDENT (90 HOURS)
- Expositive lessons (individual freelance study or in a group): 45 hours
- Interactive lessons (resolution of financial years, or other works): 33 hours
- Tutorships (doubts orientation and resolution): 3 hours
-Preparation of the Examination of theory and problems: 9 hours
Review or updating in basical mathematics (infinitesimal and coordinate geometry calculation), physics (mechanic, electricity, systems of units) and general chemistry.
Regular dedication to the study of the subject (short periods every day or every two days, better than weekly).
To avoid the introduction in a chapter without reaching a certain degree of understanding of the previous one.
To dedicate a special effort to the understanding of the meaning or nature of some strategic theoretical contents, as well as to the problems general resolution methods.
The USC virtual platform will be used as a support and complement to the theoretical-practical teaching and as an important element of communication with the student.
Juan Crugeiras Martinez
- Department
- Physical Chemistry
- Area
- Physical Chemistry
- Phone
- 881814430
- juan.crugeiras [at] usc.es
- Category
- Professor: University Lecturer
Matilde Casas Parada
- Department
- Physical Chemistry
- Area
- Physical Chemistry
- Phone
- 881815255
- matilde.casas [at] usc.es
- Category
- Professor: University Lecturer
Maria Carmen Bujan Nuñez
- Department
- Physical Chemistry
- Area
- Physical Chemistry
- Phone
- 881814228
- mariadelcarmen.bujan [at] usc.es
- Category
- Professor: University Lecturer
Juan Carlos Garcia Monteagudo
Coordinador/a- Department
- Physical Chemistry
- Area
- Physical Chemistry
- Phone
- 881814915
- juancarlos.garcia [at] usc.es
- Category
- Professor: University Lecturer
| Monday | |||
|---|---|---|---|
| 10:00-11:00 | Grupo B /CLE_02 | Spanish | 5035 Edaphology Classroom. Faculty of Pharmacy |
| 16:30-17:30 | Grupo C/CLE_03 | Spanish | 5035 Soil Science Seminar Room |
| Tuesday | |||
| 10:00-11:00 | Grupo B /CLE_02 | Spanish | 5035 Edaphology Classroom. Faculty of Pharmacy |
| 16:30-17:30 | Grupo C/CLE_03 | Spanish | 5035 Soil Science Seminar Room |
| Wednesday | |||
| 10:00-11:00 | Grupo B /CLE_02 | Spanish | 5035 Edaphology Classroom. Faculty of Pharmacy |
| 16:30-17:30 | Grupo C/CLE_03 | Spanish | 5035 Soil Science Seminar Room |
| Thursday | |||
| 10:00-11:00 | Grupo B /CLE_02 | Spanish | 5035 Edaphology Classroom. Faculty of Pharmacy |
| 16:30-17:30 | Grupo C/CLE_03 | Spanish | 5035 Soil Science Seminar Room |