ECTS credits ECTS credits: 6
ECTS Hours Rules/Memories Student's work ECTS: 99 Hours of tutorials: 3 Expository Class: 24 Interactive Classroom: 24 Total: 150
Use languages Spanish, Galician
Type: Ordinary Degree Subject RD 1393/2007 - 822/2021
Departments: Biochemistry and Molecular Biology
Areas: Biochemistry and Molecular Biology
Center Faculty of Biology
Call: First Semester
Teaching: Sin docencia (Extinguida)
Enrolment: No Matriculable
- Learn to identify and distinguish the structure, properties and function of biomolecules.
- Learn to carry out processes of purification and analysis of biomolecules.
- Identify the relationship between the structure and function of biomolecules.
- Distinguish the different classes of enzymes and their catalysis mechanisms, as well as the principles of enzymatic regulation.
- Learn to measure enzymatic activities.
- Apply the principles of thermodynamics to biological systems.
- List the mechanisms and elements of cell signalling.
Temary:
1. Biochemical science. Molecular design of life.
2. Bioenergetics: energy exchanges and high energy compounds.
3. Carbohydrates. General characteristics and biological function.
4. Nucleotides. General characteristics and biological function.
5. Lipids. General characteristics and biological function.
6. Biological membranes.
7. Amino Acids and Peptide Link.
8. Protein structure.
9. Function of proteins. Myoglobin and hemoglobin.
10. Enzymes: structure and function.
11. Enzymatic reaction. Kinetics of the enzymatic reaction.
12. Inhibition and regulation of the enzymatic reaction.
13 Introduction to metabolism and its regulation.
14. Cell signaling and signal transduction in metabolism.
Topics 4 and 13 have a duration of 1 hour, topic 11 has a duration of 3 hours and the rest have a duration of 2 hours, in total 27 hours.
In the interactive practical classes (15 h) they will be carried out in 5 compulsory 3-hour sessions. They will carry out a series of experiments with the following program:
Preparation of reagents and practice material.
Homogenization of animal tissue and fractionation of cell organelles.
Determination of protein concentration. Lowry's method.
Obtaining, purifying and analyzing DNA from eukaryotic cell nuclei.
Enzymology: kinetic and enzymatic inhibition.
At the end of the practical sessions, the results obtained will be compiled and an evaluable practice report will be prepared where the results will be properly analyzed and the questions and issues proposed in the practical guide will be answered.
The interactive seminar classes (6h) will consist of 3 seminars of 2 hours each, in which questions, practical questions, problems, and applied cases will be solved, which serve to deepen the knowledge and application of the subject matter.
The tutorials (3h) will be oriented to the resolution of the doubts generated in the expository and interactive classes. They will be carried out in a virtual way and will be used to clarify the concepts that generate greater comprehension problems, preferably at the individual level.
Basic:(corresponding to scenario 1 and 2, and the URL is recommended as the preferred scenario 3)
1-David L. Nelson, Michael M. Cox, 2018, principios de bioquímica / , 7ª ed., Barcelona : Omega, D.L.
2-Jeremy M. Berg, John L. Tymoczko, Lubert Stryer, 2015, Bioquímica : con aplicaciones clínicas / [versión española por Miguel Ángel Trueba], 7ª ed., Barcelona : Reverté, D.L.
3- Donald Voet, Judith G. Voet, Charlotte W. Pratt, 2016, Fundamentos de bioquímica : la vida a nivel molecular / , 4ª ed., Buenos Aires [etc.] : Editorial Médica Panamericana.
4-Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr., Lubert Stryer, 2019, Ninth edition, [New York] : Macmillan International Higher Education.
5-John Baynes, Marek H. DominiczakBioquímica médica / John Baynes, Marek H. Dominiczak,2019, 5ª ed., Barcelona : Elsevier, cop.
6-McKEE, T. and McKEE, J. R., 2014. Bioquímica. Las bases moleculares de la vida. [en liña] 5 ed. McGRAW-HILL Interamericana Editores. https://accessmedicina-mhmedical-com.ezbusc.usc.gal/book.aspx?bookid=19…
Complementary:
-John L. Tymoczko, Jeremy Berg, Lubert L. Stryer, 2014. Bioquímica : curso básico / [versión española por Juan Manuel González Mañas], Barcelona, [etc.] : Reverté.
-https://www.ncbi.nlm.nih.gov/books/?term=biochemistry
SKILLS
Basic / General
CB1 – Students will demonstrate to possess and understand knowledge in an area of study that starts from the base of general secondary education, and is usually found at a level that, although supported by advanced textbooks, also includes some aspects that imply knowledge coming from the vanguard of their field of study.
CB2 – Students will know how to apply their knowledge to their work or vocation in a professional manner and possess the skills that are usually demonstrated through the elaboration and defense of arguments and the resolution of problems within their area of study.
CB3 - Students will have the ability to gather and interpret relevant data (usually within their area of study) to make judgments that include a reflection on relevant social, scientific or ethical issues.
CB4 - Students will be able to transmit information, ideas, problems and solutions to a specialized and non-specialized public.
CB5 - Students will develope those learning skills necessary to undertake further studies with a high degree of autonomy.
CG1 – Students will know the most important concepts, methods and results of Biotechnology.
CG2 - Students will know how to apply both acquired theoretical and practical knowledge as well as the capacity for analysis and abstraction in the definition and posing of problems and in the search for their solutions both in academic and professional contexts.
CG3- Students will know how to collect and interpret data, information and relevant results, obtain conclusions and issue reasoned reports on problems related to Biotechnology.
CG4 – Students will be able to transmit information both in writing and orally and to discuss ideas, problems and solutions related to Biotechnology, before a general or specialized public.
CG5 – Students will be able to study and learn autonomously, with organization of time and resources, new knowledge and techniques in Biotechnology and to acquire the ability to work as a team.
Transversal
CT1 – Students will learn to think in an integrated way and approach problems from different perspectives.
CT2 – Students will learn to search, process, analyze and synthesize information from various sources.
CT4 – Students will learn to interpret experimental results and identify consistent and inconsistent elements.
CT5 – Students will learn to work as a team.
CT6 – Students will learn to reason critically.
Specific
CE2- Students will learn to understand and know how to apply the physical-chemical principles of biological processes with application in Biotechnology, as well as the main tools used to investigate them.
CE3- Students will know how to apply instrumental techniques and work protocols in a laboratory, applying the regulations and techniques related to safety and hygiene, waste management and quality.
CE4- Students will have an integrated view of the functioning of cells, including their biomolecules, metabolism, gene expression, relationship between cellular compartments, as well as communication and cell signaling mechanisms.
The subject is designed to enhance active student learning. The individual study will be carried out based on organized and detailed information provided by the teaching staff. The basis of this information will be the recommended basic bibliography, which will be supplemented, where necessary, with additional information.
In reference to the exhibition classes, they are conceived as general introductions to each topic, which will be complemented with the rest of the proposed activities. These activities are: individual study, problem solving, preparation of activities proposed in seminars. They will take place in scenario 1 in person in the classroom and in scenarios 2 and 3 preferably synchronously virtual (remotely) with the use of "teams" for their delivery, attending directly to all questions and clarifications raised by the students. The help material prepared to facilitate the monitoring and understanding of the topics (which includes the summary of the topics explained and the necessary supplementary material) are provided on the virtual campus of the USC corresponding to the subject.
The tutorials are conceived as a means of coordination and orientation of the individual work of the students. They will be carried out in a virtual way, the contact of the students with the teaching staff will be made through synchronous and / or asynchronous electronic consultations, by email and / or "teams".
In the interactive seminar classes, applications of the theory will be proposed and solved, exercises, problems, simulations of clinical cases, etc. will be carried out. Active participation of students is required. They will take place in scenario 1 in person in the classroom and in scenarios 2 and 3 in virtual synchronously (remotely). It is programmed to provide them with information and complementary material (videos, web addresses, etc.) that will allow them a better understanding of the subject.
The interactive laboratory classes according to agreement with the teaching organization of the Faculty of Biology will be in scenarios 1 and 2 of the preparation of the face-to-face practices with a duration of each practice reduced to 50% and in scenario 3 with the elaboration of 100 % of virtual practices and the duration of each practice reduced to 50%. When the situation involves conducting virtual practices, I will reorganize the practice protocols, making them more detailed, and I will provide them to you on the virtual campus of USC. I will also propose the alternative realization of the practices in a virtual way (with videos and virtual laboratories) so that they can acquire a competence and training similar to what they would have with the face-to-face format.
The methodological approach aims to know the progress of their learning and carry out their assessment. The evaluation modality will be continuous: In scenario 1 it will be face-to-face, in scenarios 2 and 3 it will preferably be telematic, the percentages being maintained in the three scenarios. "For the cases of fraudulent execution of exercises or tests will be applied or collected in the Norm of evaluation of academic performance two students and revision of qualifications". The evaluation of the subject will consist of a continuous assessment that includes the following aspects.
Continuous Assessment: Attitude will be taken into account and questions may be raised about the content developed in the expository and / or interactive classes or related topics, gradable with up to 20% of the total mark of the subject, it is an optional evaluable activity . In scenarios 2 and 3 they will be done through the Moodle platform. The competences evaluated in this part are: CB 1-5 CG 1-5 CE 2,3,4 CT 1,2,4-6.
Interactive laboratory classes: Attitude will be taken into account and a report will be prepared in which the results and their justification will be presented and analyzed. It will be graded with up to 20% of the final grade, it is an evaluable compulsory activity. The competences evaluated are: CB 1-5 CG 1-5 CE 2,3,4 CT 1,2,4-6
Final test: There will be a final test on the subject developed throughout the course (lectures, seminars, etc.). In scenarios 2 and 3 they will be done through the Moodle platform. The grade will be up to 60% of the final grade, it is a compulsory evaluable activity. In it the competences will be evaluated: CB 1-5 CG 1 CE 2,3,4 CT 1,2,4-6
Horas presenciales: 54 horas.
27 horas clases expositivas, 15 horas de interactivas de laboratorio, 6 horas interactivas de seminarios, 3 horas de tutorías,
Horas no presenciales: 99 horas.
76 horas de dedicación al estudio individual y la elaboración de trabajos y 3 horas para tutorías, 20 horas para la elaboración de informes de prácticas.
Volumen total de trabajo: 150 horas totales (25 horas / ECTS x 6 ECTS = 150 horas).
Attendance and active participation in class is recommended. Study and weekly review of the subject taught. Use of the recommended bibliography, as well as the graphic material provided by the teacher, essential for understanding the subject.
Frequent reading and reflection on the subject taught, necessary for the integration of knowledge in this field of science.
Interest and attention on new advances in this discipline spread through the media, for incorporation and discussion in classes and seminars.
"Contingency Plan"
In scenario 1 the lectures and classes and seminars will be carried out synchronously in the classroom and in scenarios 2 and 3 will preferably be telematic. The tutorials will be carried out virtually through synchronous and / or asynchronous electronic consultations.
The interactive laboratory classes will be in scenario 1 and 2 with the preparation of all face-to-face practices with a duration of practices reduced to 50% and in scenario 3 with the preparation of 100% of virtual practices and the duration of each practice reduced to 50%.
The evaluation modality will be continuous: In scenario 1 it will be face-to-face, in scenarios 2 and 3 it will be telematic, the percentages being maintained in the three scenarios. "For the cases of fraudulent execution of exercises or tests will be applied or collected in the Norm of evaluation of academic performance two students and revision of qualifications". The evaluation of the subject will consist of a continuous assessment that includes the following aspects.
Continuous Assessment: Attitude will be taken into account and questions may be raised about the content developed in the expository and / or interactive classes or related topics, gradable with up to 20% of the total mark of the subject, it is an optional evaluable activity . In scenarios 2 and 3 they will be done through the Moodle platform. The competences evaluated in this part are: CB 1-5 CG 1-5 CE 2,3,4 CT 1,2,4-6.
Interactive laboratory classes: Attitude will be taken into account and a report will be prepared in which the results and their justification will be presented and analyzed. It will be graded with up to 20% of the final grade, it is an evaluable compulsory activity. The competences evaluated are: CB 1-5 CG 1-5 CE 2,3,4 CT 1,2,4-6
Final test: There will be a final test on the subject developed throughout the course (lectures, seminars, etc.). In scenarios 2 and 3 they will be done through the Moodle platform. The grade will be up to 60% of the final grade, it is a compulsory evaluable activity. In it the competences will be evaluated: CB 1-5 CG 1 CE 2,3,4 CT 1,2,4-6
Ma Del Pilar Arias Crespo
Coordinador/a- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- Phone
- 881816933
- pilar.arias [at] usc.es
- Category
- Professor: University Lecturer
Maria Lourdes Dominguez Gerpe
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- ml.dominguez.gerpe [at] usc.es
- Category
- Professor: Temporary supply professor to reduce teaching hours
| Monday | |||
|---|---|---|---|
| 18:00-19:00 | Grupo /CLE_01 | Spanish | Virtual classroom |
| Wednesday | |||
| 16:00-17:00 | Grupo /CLE_01 | Spanish | Virtual classroom |
| 01.11.2021 10:00-14:00 | Grupo /CLE_01 | Classroom 05 (video-conference). Rita Levi Montalcini |
| 01.11.2021 10:00-14:00 | Grupo /CLE_01 | Classroom 06. Diane Fosey and Jane Goodall |
| 01.11.2021 10:00-14:00 | Grupo /CLE_01 | Classroom 07. Konrad Lorenz |
| 06.22.2021 10:00-14:00 | Grupo /CLE_01 | Classroom 01. Charles Darwin |