ECTS credits ECTS credits: 4
ECTS Hours Rules/Memories Student's work ECTS: 60 Hours of tutorials: 2 Expository Class: 22 Interactive Classroom: 16 Total: 100
Use languages Spanish, Galician
Type: Ordinary subject Master’s Degree RD 1393/2007 - 822/2021
Departments: Functional Biology
Areas: Cellular Biology
Center Faculty of Biology
Call: First Semester
Teaching: With teaching
Enrolment: Enrollable
-To know the basis of the cellular and subcellular organization of the neurons and glial cells.
-To know the basis of the neuronal polarity and its functional implications
-To understand as the information and material is transfer between the different functional domains of the neurons.
-To Know the processes that originate and support the functional architecture of the nervous system cells.
-To know the actual concepts, and the basis of the techniques use in this field, and the relation of the cell biology with other disciplines of neuroscience.
-To think about what the advances in the knowledge of nervous cells help to improve the knowledge of the function of nervous system in normal and pathological conditions, an in new therapies.
PROGRAMME OF THEORETICAL CLASSES
1- Cell biology of the nervous system. General characteristics and cell types of the nervous tissue. Molecular and cell biology techniques used in Neuroscience.
2.- Cell surface.- Plasmatic membrane
3.- Inside the cell. Substances traffic in the neurons. Biosynthesis, storage, release and inactivation of neurotransmitters
4.- Cytoskeleton of the neurons. Axonal transport.
5.- Soma. Dendrites and dendritic spines.
6.- Axon; Initial segment, Ranvier node, paranodes, yuxtaparanodes and internodal region.
7.- Axonic terminal. Chemical synapses. Postsynatic specializations. Biosynthesis, storage, release and inactivation of neurotransmitters. Electrical synapses
8.- Genic expression in the nervous system and regulation.
9.- Cell cycle in the cells of the nervous tissue.
10.- Aging and apoptosis of the nervous tissue cells.
11.- Astroglia: Morphology and classification. Cell biology. Function.
12.- Oligodendrocytes: Morphology and classification. Cell biology. Function.
13. Microglial cells.
14.- Schwann cells: Morphology and cell biology.
BASIC TEXTBOOKS
ALBERTS, B.; BRAY, D.; LEWIS, J.; RAFF, M.; ROBERTS, K. e WATSON, J. D. (Eds). Biología Molecular de la Célula, 3ª edición, Omega, 1996.
ALBERTS, B., JOHNSON, A., LEWIS, J., RAFF, M., ROBERTS, K., WALTER, P. (Eds). Molecular biology of the cell. Fourth edition. Garland Science, Taylor Francis Group, New York, 2002.
COOPER, G. M., La Célula, Editorial Marbán, Madrid, 2001.
TEXTS OF CELL BIOLOGY OF THE NERVOUS SYSTEM
CASTELLANO, B., GONZALEZ, B., NIETO-SAMPEDRO, M. (Eds). Understanding Glial Cells. Kluwer Academic Publishers. Dordrecht (Netherlands), 1998.
BEAN, A.J.(Ed.). Protein trafficking in neurons. Elsevier Academic Press (USA), 2007.
COWAN, W.M., SÜDHOF, T.C., STEVENS, C.F. (Eds). Synapses. The Johns Hopkins University Press, Baltimore, 2001.
DAVIES, R.W., MORRIS, B.J. (Eds). Molecular biology of the neuron. Second Edition. Oxford University Press, New York, 2006.
HALL, Z.W. (Eds). An introduction to molecular neurobiology. Sinauer Associates, INC. Publishers, Sunderland, Massachusetts, 1992.
JESERICH, G., ALTHAUS, H.H., RICHTER-LANDSBERG, C., HEUMANN, R. (Eds). Molecular Signalling and Regulation in Glial Cells. Springer-Verlag Berlin Heidelberg New York, 1997.
KANDEL, E.R., SCHWARTZ, J.H., JESSEL, T.M. (Eds). Principles of Neural Science. Fourth edition. McGraw-Hill Companies, 2000.
KETTENMANN, H., RANSOM, B.R. (Eds). Neuroglia. Oxford University Press, New York, Oxford, 1995.
LEVITAN, I.B., KACZMAREK, L.K. The Neuron. Cell and Molecular Biology. Third edition. Oxford Universtity Press, New York, 2002.
PURVES, D., AUGUSTINE, G.J., FITPATRICH, D., HALL, W.C., LAMANTIA, A., MCNAMARA, J.O., WILLIAMS, S.M. Neurociencia. Third edition. Editorial Medica Panamericana S.A., Madrid, España, 2007.
MACNAMARA, J.O., WILLIAMS, S.M. Neurociencia. Third edition. Editorial Medica Panamericana S.A., Madrid, España, 2007.
SIEGEL, G.J., ALBERS, R.W., BRADY, S.T., PRICE, D.L (Eds). Basic neurochemistry. Molecular, cellular and medical aspects. Seventh edition. Elsevier Academic Press (USA), 2006.
SQUIRE, L.R., BLOOM, F.E., McCONNEL, S.K., ROBERTS, J.L., SPITZER, N.C., ZIGMOND, M.J. (Eds). Fundamental Neuroscience. Second edition. Academic Press, an imprint of Elsevier Science (USA), 2003.
ZIGMOND, M.J. (EDS). Fundamental Neuroscience. Second Edition. Academic Press, an imprint of Elsevier Science (USA), 2003
STUART, G., SPRUSTON, N., HÄUSER, M. (Eds). Dendrites. Oxford University Press Inc., New York, 1999.
The student must acquire and improve the following competences and abilities:
- Personal commitment to learn.
- Analysis, synthetic and critical skills.
- Ability to analyse information from different sources.
- Capacity to apply theoretical knowledge into practice.
- Ability to work autonomously as well as in a team.
Teaching methodology:
- Theoretical sessions.
- Seminars, in which the discussion of articles and the resolution of questionnaires related to each of the subjects, and four of the 8 seminars will have to be delivered for correction, and evaluation.
Students must pass an exam that will account for 80% of the final score, and this exam will consist of a multiple choice test, together with short answer questions, and it will also be possible to include questions with diagrams and figures. This test will also include questions related to the seminars.
- The score obtained in the 4 seminars delivered, will represent 20% of the final grade.
The final score of the student in the course will result from the sum:
Exam (80%) + Seminars (20%), this sum will only be made when the student achieves a score equal to or higher than 5 in the exam, otherwise the summation of the exam score and the seminar score will not be made. In the latter case, the score used for the final score will correspond to the score of the exam.
Presential time in the class:
- Teorethical sessions: 31 presential hours.
- Seminars: 8 presential hours.
- Personalized tutorial sessions: 1 hour.
- Theoretical exam: 2 hours.
Individual work of the student:
-45 hours of study
-10,5 hours to elaborate works, seminars
-4,5 hours to preparate the exams
- Students without knowledge in cell biology should work with basic books and assist to the personalized tutorial sessions.
-Assistance and active participation in the theoretical sessions and seminars.
-Study periodical review of the bibliographic material and information received during the course
-To clarify any questions and doubts with the teachers.
Contigency Plan
Methodology:
Scenario 2.- The same calendar and time distribution will be followed as in scenario 1. Synchronous sessions will be held (expository classes and seminars) that may be classroom or virtual through the Ms Teams platform, based on the number of students enrolled, rotating student shifts may be established in the classroom.
Scenario 3.- The same calendar and time distribution will be followed as in scenario 1. All sessions (expository classes and seminars) will be held virtually (synchronously) through the Ms Teams platform.
In the three scenarios, the students will have access to the material (presentations of expository classes and seminars) through the Virtual Campus; The delivery of activities will also take place through the virtual campus.
Evaluation:
The learning assessment system will be the same in the three scenarios, but in scenario 2 and 3 all the assessment activities contemplated will take place telematically with visual and audio monitoring of the students through Ms Teams. These tests will include the necessary adaptations (limitation of the response time, plagiarism controls....) to ensure fairness and the correct development of the exams. If technical or personal impediments arise that hinder the reliable control of these exams, alternatives of an oral nature with recording will be offered, in order to leave a documentary record of them. The recording may be extended, if necessary, to the review sessions.
Miguel Angel Rodriguez Diaz
Coordinador/a- Department
- Functional Biology
- Area
- Cellular Biology
- Phone
- 881816942
- miguelangel.rodriguez.diaz [at] usc.es
- Category
- Professor: Temporary PhD professor
| Monday | |||
|---|---|---|---|
| 16:00-17:00 | Grupo /CLE_01 | Spanish | Classroom 05 (video-conference). Rita Levi Montalcini |
| 18:00-19:00 | Grupo /CLE_01 | Spanish | Classroom 05 (video-conference). Rita Levi Montalcini |
| Tuesday | |||
| 18:00-19:00 | Grupo /CLE_01 | Spanish | Classroom 05 (video-conference). Rita Levi Montalcini |
| Thursday | |||
| 18:00-19:00 | Grupo /CLE_01 | Spanish | Classroom 05 (video-conference). Rita Levi Montalcini |
| 12.11.2020 16:00-18:00 | Grupo /CLE_01 | Classroom 05 (video-conference). Rita Levi Montalcini |
| 06.17.2021 11:30-13:30 | Grupo /CLE_01 | Classroom 05 (video-conference). Rita Levi Montalcini |