ECTS credits ECTS credits: 3
ECTS Hours Rules/Memories Student's work ECTS: 45 Hours of tutorials: 1 Expository Class: 25 Interactive Classroom: 4 Total: 75
Use languages Spanish, Galician
Type: Ordinary subject Master’s Degree RD 1393/2007 - 822/2021
Departments: Pharmacology, Pharmacy and Pharmaceutical Technology
Areas: Pharmacology
Center Faculty of Biology
Call: Second Semester
Teaching: With teaching
Enrolment: Enrollable | 1st year (Yes)
The student must achieve the following objectives:
- Ability to apply the general principles of neuropharmacology to real situations
- Ability / capacity to work individually, in small groups and in multidisciplinary teams, combining specialized, intermediate and overall views.
- Ability to access sources of information.
General principles of pharmacology and neuropharmacology
Theoretical contents
1. Introduction to pharmacological sciences
2. Basic pharmacokinetics. Factors determining absorption, distribution,
metabolism and excretion of drugs. Passage of the blood-brain barrier and access of drugs to the central nervous system.
3. General pharmacodynamics. General mechanisms of drug action, specific and non-specific drugs. Nucleic and proteic target sites.
4. Research and development of drugs in neuropsychopharmacology Required steps
for a new drug to be approved for human use.
5.Psychiatric pharmacology
Pharmacology of anxiety and insomnia, depression, schizophrenia, dependencies, disorders and phobias, etc.
6.Pharmacology of neurological diseases
Pharmacology of movement disorders, cognitive impairment, dementia, seizures. Parkinson's disease, Alzheimer's disease, epilepsy, etc.
Practical contents
Sharing and discussion sessions will be held in which students will prepare and present their work on the selected topics, using the standard methodologies and formats provided by the teachers in which they will incorporate their own vision after the bibliographic searches.
-Millan MJ, Goodwin GM, Meyer-Lindenberg A, Ove Ogren S. Learning from the past and looking to the future: Emerging perspectives for improving the treatment of psychiatric disorders. Eur Neuropsychopharmacol. 2015 May; 25(5):599-656.
-Ahmed AO, Bhat IA. Psychopharmacological treatment of neurocognitive deficits in people with schizophrenia: a review of old and new targes. CNS Drugs. 2014 Apr;28(4):301-18.
-Stahl, S.M. Essential psychopharmacology, 4th edition. Cambridge University Press, Cambridge, MA, 2014
-Paul SM et al., How to improve R&D productivity: the pharmaceutical industry's grand challenge. Nature Reviews in Drug Discovery 2010; 9:203-214
-Dugger SA, et al. Drug development in the era of precision medicine. Nature Reviews in Drug Discovery 2018; 17:183-196
-Mohs RC and Greig NH. Drug discovery and development: Role of basic biological research. Alzheimer's & Dementia: Translational Research and Clinical Interventions 2017; 3:651-657
-Hunter AJ et al. Open innovation in neuroscience research and drug discovery. Brain and neuroscience advances 2018; 2:1-6
After completing the course, students will be able to:
- Describe the therapeutic targets, receptors, channels, transporters, enzymes, as well
as their signalling routes and the transductional mechanisms relevant to
actions of drugs.
- Describe how drugs, at the molecular level, affect the transmission of signals in
neuropsychiatric disorders, their mechanisms and actions.
- Describe the effects of drugs on the signs and symptoms of the
neuropsychiatric disorders and their relationship to their molecular mechanisms of action.
Face-to-face work in the classroom
Hours of lectures: 22
Hours of interactive classes: Seminars: 4
Tutorials in small groups or individualized: 1
Evaluation activities: 3
Student's personal work
Individual study: 35
Elaboration of reports of practices, works: 10
Total student's personal working hours: 45
- Final exam (30% of the final mark): students must pass an exam on the contents of the course, the pass mark is 5 out of 10.
- Teamwork (50% of the final mark): the students must participate in the teams that are formed and take responsibility for the adequate performance of the corresponding work, which will be assigned by mutual agreement between them. In addition, they must participate in the presentations that correspond to them.
- Continuous evaluation (20% of the final grade). Attendance is compulsory. The participation/ involvement of the student throughout the course will be taken into account.
See teaching methodology
Study the contents to solve the conceptual doubts. It is important to relate the basic concepts along the way.
Use the recommended bibliography and clarify concepts to consolidate knowledge and acquire skills in problem solving.
Contingency plan
SCENARIO 2: DISTANCING
Expository and interactive teaching
Teaching can also be carried out either in person or virtually with synchronous or asynchronous procedures.
Tutorials
Priority will be given to the programming of tutorials by telematic means
Evaluation
On-site or telematic depending on conditions and number of students
SCENARIO 3: CLOSURE OF THE FACILITIES
Expository and interactive teaching
Teaching would be approached virtually with synchronous or asynchronous procedures.
Tutorials
Telematic
Evaluation
Telematic
In cases of fraudulent completion of exercises or tests, the provisions of the USC regultation “Normativa de avaliación do rendemento académico dos estudantes e de revisión de cualificacións” will be applicable.
Jose Angel Fontenla Gil
- Department
- Pharmacology, Pharmacy and Pharmaceutical Technology
- Area
- Pharmacology
- Phone
- 881814898
- joseangel.fontenla [at] usc.es
- Category
- Professor: University Lecturer
Maria Isabel Loza Garcia
Coordinador/a- Department
- Pharmacology, Pharmacy and Pharmaceutical Technology
- Area
- Pharmacology
- Phone
- 881815005
- mabel.loza [at] usc.es
- Category
- Professor: University Professor
| Wednesday | |||
|---|---|---|---|
| 16:00-19:00 | Grupo /CLE_01 | Spanish | Classroom 05 (video-conference). Rita Levi Montalcini |
| 05.11.2022 16:00-19:00 | Grupo /CLE_01 | Classroom 05 (video-conference). Rita Levi Montalcini |
| 06.21.2022 17:00-19:00 | Grupo /CLE_01 | Classroom 05 (video-conference). Rita Levi Montalcini |